ChemicalBook > CAS DataBase List > 2,4-Dichlorobenzyl alcohol

2,4-Dichlorobenzyl alcohol

Product Name: 2,4-Dichlorobenzyl alcohol
CAS No.: 1777-82-8
Chemical Name: 2,4-Dichlorobenzyl alcohol
Synonyms: Myacide;Dybenal;myacidesp;Rapidosept;DYBENAL(R);RARECHEM AL BD 0019;2,4-Dichlorobenzyl a;Oxiconazole USP RC D;LABOTEST-BB LT01985654;Miconazole Impurity 14
CBNumber: CB4156352
Molecular Formula: C7H6Cl2O
Formula Weight: 177.03
MOL File: 1777-82-8.mol

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2,4-Dichlorobenzyl alcohol Property

Melting point:: 55-58 °C(lit.)
Boiling point:: 150 °C (25 mmHg)
Density: 1.2970 (rough estimate)
vapor pressure: 0.154Pa at 25℃
refractive index: 1.5756 (estimate)
Flash point:: >230 °F
storage temp.: 2-8°C
solubility: 1g/l
pka: 13.60±0.10(Predicted)
form: Solid
color: White to Off-White
Water Solubility: Soluble in water, methanol and chloroform.
Merck: 14,3060
BRN: 1448652
InChIKey: DBHODFSFBXJZNY-UHFFFAOYSA-N
LogP: 2.8 at 24℃
CAS DataBase Reference: 1777-82-8(CAS DataBase Reference)
EPA Substance Registry System: 2,4-Dichlorobenzenemethanol (1777-82-8)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 24/25
WGK Germany: 2
RTECS: DO0890000
Hazard Note: Irritant
HS Code: 29062900
Toxicity: mouse,LD50,oral,2300mg/kg (2300mg/kg),Cosmetics and Toiletries. Vol. 95(6), Pg. 59, 1980.

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H318Causes serious eye damage

H332Harmful if inhaled

H412Harmful to aquatic life with long lasting effects

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: Y0001620
Product name: 2,4-Dichlorobenzyl alcohol
Purity: European Pharmacopoeia (EP) Reference Standard
Packaging: 250 mg
Price: $225
Updated: 2025/07/31

Sigma-Aldrich

Product number: 146668
Product name: 2,4-Dichlorobenzyl alcohol
Purity: 99%
Packaging: 50g
Price: $153
Updated: 2025/07/31

Sigma-Aldrich

Product number: Y0001620
Product name: 2,4-Dichlorobenzyl alcohol
Purity: European Pharmacopoeia (EP) Reference Standard
Packaging: y0001620
Price: $220
Updated: 2024/03/01

TCI Chemical

Product number: D1837
Product name: 2,4-Dichlorobenzyl Alcohol
Purity: >97.0%(GC)
Packaging: 25g
Price: $38
Updated: 2025/07/31

TRC

Product number: R124500
Product name: Rapidosept
Packaging: 100g
Price: $180
Updated: 2021/12/16

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2,4-Dichlorobenzyl alcohol Chemical Properties,Usage,Production

Chemical Properties

white to light yellow crystal powde

Uses

An surgical antiseptic.

Uses

2,4-Dichlorobenzyl alcohol is an antiseptic found in commercially available throat lozenges. Also used deactivate Respiratory syncytial virus and SARS-Cov.

Definition

ChEBI: A member of the class of benzyl alcohols that is benzyl alcohol in which the hydrogens at positions 2 and 4 are replaced by chlorines.

General Description

2,4-Dichlorobenzyl alcohol is a constituent of commercially available lozenges for acute sore throat caused by upper respiratory tract infections.

Mechanism of action

In-vitro evidence has demonstrated the virucidal effect of Amylmetacresol (AMC) and 2,4-dichlorobenzyl alcohol (DCBA) on a number of viruses associated with the common cold; a reduction in viral load is believed to have benefits in reducing the symptoms. The local anesthetic action of AMC/DCBA throat lozenges, a combination of the potent channel blocker – AMC and the reduced potency for sodium channel blockade DCBA – attenuate the effects of AMC, possibly as a result of competitive binding, which acts on a sodium channel blocker, and may be effective in relieving symptoms due to inflammation. Therefore, AMC/DCBA throat lozenge is thought to represent a useful option to meet patients' needs and avoid unnecessary prescription of antibiotics[1].

Clinical Use

Amylmetacresol and 2,4-dichlorobenzyl alcohol throat lozenges have been marketed in many countries worldwide for pain relief in acute sore throat. Amylmetacresol and 2,4-dichlorobenzyl alcohol throat lozenges have been shown to be safe and efficient in relieving of acute sore throat symptoms, and it produces an immediate symptomatic relief. Local symptomatic pain relief plays an important role in managing acute sore throat[1-2].

Side effects

COMMON SIDE EFFECTS: Difficulty in breathing, Tongue soreness, Hypersensitivity reactions, Swelling of the face, Tongue, Throat and Neck.

References

[1] Ting W Tan. “Effectiveness of amylmetacresol and 2,4-dichlorobenzyl alcohol throat lozenges in patients with acute sore throat due to upper respiratory tract infection: a systematic review protocol.” JBI database of systematic reviews and implementation reports (2017): 862–872.
[2] Thomas, Michael J. “ACP Journal Club. Amylmetacresol and 2, 4-dichlorobenzyl alcohol lozenges were better than placebo lozenges for relief of acute sore throat.” Annals of Internal Medicine 153 4 (2010): JC2-6.

2,4-Dichlorobenzyl alcohol Preparation Products And Raw materials

Raw materials

Preparation Products

Imazalil

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View Lastest Price from 2,4-Dichlorobenzyl alcohol manufacturers

Hebei Chuanghai Biotechnology Co., Ltd

Product: 2,4-Dichlorobenzyl alcohol 1777-82-8
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2025-03-10

Hebei Chuanghai Biotechnology Co., Ltd

Product: 2,4-Dichlorobenzyl alcohol 1777-82-8
Price: US $30.00-10.00/KG
Min. Order: 50KG
Purity: 99%
Supply Ability: 500000kg
Release date: 2024-10-24

Hebei Zhuanglai Chemical Trading Co.,Ltd

Product: 2, 4-Dichlorobenzyl Alcohol 1777-82-8
Price: US $180.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20ton
Release date: 2024-06-03

1777-82-8, 2,4-Dichlorobenzyl alcoholRelated Search:

4-Hydroxybenzyl alcohol 4-Methoxybenzyl alcohol 4,4'-Bis(chloromethyl)-1,1'-biphenyl 4-Nitrobenzyl alcohol 1,3-Bis(chloromethyl)benzene Thionyl chloride Dichloroethane Triphenylmethanol 4,6-Dichloropyrimidine Ethyl acetate Dichloroacetic acid Benzyl alcohol 2,3-DICHLOROBENZYL ALCOHOL 99%,2,3-DICHLOROBENZYL ALCOHOL Miconazole Impurity Isoconazole Miconazole IMpurity I alpha-(2,4-Dichlorophenyl)-1H-imidazole-1-ethanol Miconazole IMpurity H

2,4-dichloro-benzylalcoho

benzylalcohol,2,4-dichloro-

myacidesp

2,4-DichlorobenzylAlcohol99%

Benzenemethanol, 2,4-dichloro-

2,4-DICHLOROBENZL ALCOHOL

30) 2,4-DICHLORO BENZYL ALCOHOL

Rapidosept

Myacide

2,4-Dichlorobenzyl a

4-Dichlorobenzyl alcohol

Miconazole Related Compound (2,4-Dichlorobenzyl Alcohol)

(2,4-DICHLOROPHENYL)METHANOL

2,4-Dichloro-benzenemethanol

2,4-DICHLOROBENZYL ALCOHOL

2,4-DICHLOROBENZOYL ALCOHOL

LABOTEST-BB LT01985654

Dybenal

DYBENAL(R)

RARECHEM AL BD 0019

Miconazole Nitrate Impurity A

2,4-Dichlorobenzyl Alcohol &gt

2,4-Dichlorobenzyl alcohol CRS

Oxiconazole USP RC D

Miconazole Impurity 14

Oxiconazole Related Compound D

Oxiconazole USP Related Compound D

2,4-Dichlorbenzylalkohol

2, 4 – DICHLORO BENZYL ALCOHOL – BP/EP

C12410500 2,4-DichlorobenzyLalcohol

Miconazole Nitrate Impurity 10

Miconazol-related Compound 6 (2, 4-dichlorobenzyl alcohol)

Oxiconazole Impurity 4 (Oxiconazole USP RC D)

Oxiconazole Impurity 4

1777-82-8

1777-24-6

1777-83-8

C7H6Cl2O

C7 to C8

Alcohols

Building Blocks

Organic Building Blocks

Oxygen Compounds

Aromatics

Intermediates & Fine Chemicals

Pharmaceuticals

Building Blocks

C7 to C8

Chemical Synthesis

Organic Building Blocks

Oxygen Compounds

Benzhydrols, Benzyl & Special Alcohols

Alcohols

C7 to C8

Oxygen Compounds