1-(2-Methoxyphenyl)piperazine hydrochloride
- Product Name
- 1-(2-Methoxyphenyl)piperazine hydrochloride
- CAS No.
- 5464-78-8
- Chemical Name
- 1-(2-Methoxyphenyl)piperazine hydrochloride
- Synonyms
- OMPP;TIMTEC-BB SBB003293;Urapidil Impurity B;)piperazine hydrochL;LABOTEST-BB LT00159868;Urapidil Impurity 6 HCl;1,3-dimethyl-17-nitrosourea;2-MethoxyphenylPiperazineHCl;o-Methoxyphenyl Piperazine HCl;1-(2-Methoxylphenyl)-Piperazin
- CBNumber
- CB4166128
- Molecular Formula
- C11H17ClN2O
- Formula Weight
- 228.71848
- MOL File
- 5464-78-8.mol
1-(2-Methoxyphenyl)piperazine hydrochloride Property
- Melting point:
- 217-219 °C(lit.)
- Boiling point:
- 130-133C
- Density
- 1.106g/cm
- refractive index
- 1,574-1,576
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- Soluble in DMSO and Methanol.
- form
- A crystalline solid
- Sensitive
- Hygroscopic
- BRN
- 4276925
- InChI
- InChI=1S/C11H16N2O.ClH/c1-14-11-5-3-2-4-10(11)13-8-6-12-7-9-13;/h2-5,12H,6-9H2,1H3;1H
- InChIKey
- DDMVHGULHRJOEC-UHFFFAOYSA-N
- SMILES
- N1(C2=CC=CC=C2OC)CCNCC1.[H]Cl
- CAS DataBase Reference
- 5464-78-8(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 270067
- Product name
- 1-(2-Methoxyphenyl)piperazine hydrochloride
- Purity
- 97%
- Packaging
- 100g
- Price
- $80.5
- Updated
- 2025/07/31
- Product number
- M3643
- Product name
- 1-(2-Methoxyphenyl)piperazine Hydrochloride
- Packaging
- 5G
- Price
- $39
- Updated
- 2025/07/31
- Product number
- M3643
- Product name
- 1-(2-Methoxyphenyl)piperazine Hydrochloride
- Packaging
- 25G
- Price
- $117
- Updated
- 2025/07/31
- Product number
- JK956738
- Product name
- 1-(2-Methoxyphenyl)piperazine hydrochloride
- Purity
- 99%
- Packaging
- 25g
- Price
- $32
- Updated
- 2021/12/16
- Product number
- 075374
- Product name
- 1-(2-Methoxyphenyl)piperazine hydrochloride
- Purity
- 95+%
- Packaging
- 100g
- Price
- $116
- Updated
- 2021/12/16
1-(2-Methoxyphenyl)piperazine hydrochloride Chemical Properties,Usage,Production
Chemical Properties
1-(2-Methoxyphenyl)piperazine hydrochloride is Off-White Solid
Uses
1-(2-Methoxyphenyl)piperazine hydrochloride is used as reference material for forensic laboratories. It is used in chemical synthesis studies.
Synthesis
95520-98-2
5464-78-8
Procedure for the synthesis of compound 6: In a double necked round bottom flask (RB flask), tert-butyl 4-(2-methoxyphenyl)piperazine-1-carboxylate (Compound 5, 0.600 g, 0.00205 mol, 1 equiv.) was dissolved in ethyl ether (10 mL) followed by addition of ethyl ether hydrochloric acid solution. The reaction mixture was stirred at room temperature overnight. The progress of the reaction was monitored by thin layer chromatography (TLC) and after confirming complete consumption of the raw material, the ether was removed by evaporation under reduced pressure to give a solid product. The solid product was washed with ethyl acetate and then dried to give the final 1-(2-methoxyphenyl)piperazine hydrochloride (compound 6) as a white solid (0.425 g, 90.08% yield).
References
[1] Patent: US2010/331307, 2010, A1. Location in patent: Page/Page column 19
[2] Patent: WO2011/72174, 2011, A1. Location in patent: Page/Page column 100
[3] Patent: WO2012/3418, 2012, A2. Location in patent: Page/Page column 92
1-(2-Methoxyphenyl)piperazine hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 1-(2-Methoxyphenyl)piperazine hydrochloride manufacturers
- Product
- 1-(2-Methoxyphenyl)piperazine hydrochloride 5464-78-8
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-11-20
- Product
- 1-(2-Methoxyphenyl)piperazine hydrochloride 5464-78-8
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2025-04-01
- Product
- Urapidil Impurity 18(Hydrochloride) 5464-78-8
- Price
- US $0.00/mg
- Min. Order
- 10mg
- Purity
- 0.98
- Supply Ability
- 10g
- Release date
- 2024-04-03