HUMAN MCP-4

HUMAN MCP-4 Property

storage temp. 

−20°C

form 

lyophilized powder

biological source

human

Safety

Hazard Codes 

T

Risk Statements 

23/24/25-36/37/38

Safety Statements 

26-36/37/39-45

Hazard and Precautionary Statements (GHS)

HUMAN MCP-4 Chemical Properties,Usage,Production

Description

Macrophage Inflammatory Protein-4 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 69 amino acids and having a molecular mass of 7813 Dalton.
The MIP-4 is purified by proprietary chromatographic techniques.

Source

Escherichia Coli

Background

Chemokine (C-C motif) ligand 13 (CCL13 / MCP-4) is a small cytokine belonging to the CC chemokine family. The MCP-4 gene is located on human chromosome 17 within a large cluster of other CC chemokines. MCP-4 induces chemotaxis in monocytes, eosinophils, T lymphocytes, and basophils by binding cell surface G-protein linked chemokine receptors such as CCR2, CCR3 and CCR5. Activity of the MCP-4 chemokine has been implicated in allergic reactions such as asthma. MCP-4 can be induced by the inflammatory cytokines interleukin-1 and TNF-a.