Bis(3-methylsalicylic acid)1,1,3,3-tetrabutyl-1,3-distanna-2-oxapropane-1,3-diyl ester

Product Name: Bis(3-methylsalicylic acid)1,1,3,3-tetrabutyl-1,3-distanna-2-oxapropane-1,3-diyl ester
CAS No.: 1620951-72-5
Chemical Name: Bis(3-methylsalicylic acid)1,1,3,3-tetrabutyl-1,3-distanna-2-oxapropane-1,3-diyl ester
Synonyms: PA-1;PA1 2HCl;PA-1 2HCl,PA1 2HCl;Bis(3-methylsalicylic acid)1,1,3,3-tetrabutyl-1,3-distanna-2-oxapropane-1,3-diyl ester
CBNumber: CB42350909
Molecular Formula: C32H50O7Sn2
Formula Weight: 784.1552
MOL File: 1620951-72-5.mol

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Bis(3-methylsalicylic acid)1,1,3,3-tetrabutyl-1,3-distanna-2-oxapropane-1,3-diyl ester Property

storage temp.: -196°C

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Hazard and Precautionary Statements (GHS)

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Bis(3-methylsalicylic acid)1,1,3,3-tetrabutyl-1,3-distanna-2-oxapropane-1,3-diyl ester Chemical Properties,Usage,Production

Uses

PA1 is a photoswitchable epithelial sodium channel (ENaC) blocker. PA1 can switch to cis-PA1 at 400nm and trans-PA1 at 500nm. PA1 inhibits δ/αENaC, αβγENaC, and δβγENaC, with IC50 values of 4.3nM, 90 nM, and 390 nM, respectively[1].

References

[1] Matthias Sch?nberger, et al. Controlling epithelial sodium channels with light using photoswitchable amilorides. Nat Chem. 2014 Aug;6(8):712-9. DOI:10.1038/nchem.2004

Bis(3-methylsalicylic acid)1,1,3,3-tetrabutyl-1,3-distanna-2-oxapropane-1,3-diyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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Bis(3-methylsalicylic acid)1,1,3,3-tetrabutyl-1,3-distanna-2-oxapropane-1,3-diyl ester Suppliers

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1620951-72-5, Bis(3-methylsalicylic acid)1,1,3,3-tetrabutyl-1,3-distanna-2-oxapropane-1,3-diyl esterRelated Search:

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Bis(3-methylsalicylic acid)1,1,3,3-tetrabutyl-1,3-distanna-2-oxapropane-1,3-diyl ester

PA-1

PA1 2HCl

PA-1 2HCl,PA1 2HCl

1620951-72-5