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Tradipitant

Product Name
Tradipitant
CAS No.
622370-35-8
Chemical Name
Tradipitant
Synonyms
VLY 686;LY686017;Biafungin;Tradipitant;VLY-686;LY686017;Tradipitant(VLY-686);Tradipitant, 10 mM in DMSO;tradipitant,VLY-686, LY686017;(2-(1-(3,5-Bis(trifluoromethyl)benzyl)-5-(pyridin-4-yl)-1H-1,2,3-triazol-4-yl)pyridin-3-yl)(2-;VLY 686,LY-686017,Neurokinin Receptor,VLY686,LY 686017,Inhibitor,Tradipitant,NK receptor,Tachykinin receptor,inhibit
CBNumber
CB42731153
Molecular Formula
C28H16ClF6N5O
Formula Weight
587.9
MOL File
622370-35-8.mol
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Tradipitant Property

Melting point:
143 - 145°C
Boiling point:
640.9±65.0 °C(Predicted)
Density 
1.45±0.1 g/cm3(Predicted)
storage temp. 
Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility 
Chloroform (Slightly), Ethyl Acetate (Slightly)
form 
Solid
pka
2.92±0.10(Predicted)
color 
Pale Beige to Brown
InChIKey
CAVRKWRKTNINFF-UHFFFAOYSA-N
SMILES
C(C1=CC=CN=C1C1=C(C2C=CN=CC=2)N(CC2=CC(C(F)(F)F)=CC(C(F)(F)F)=C2)N=N1)(C1=CC=CC=C1Cl)=O
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
T719025
Product name
Tradipitant
Packaging
10mg
Price
$305
Updated
2021/12/16
ChemScene
Product number
CS-8056
Product name
Tradipitant
Purity
99.63%
Packaging
5mg
Price
$150
Updated
2021/12/16
ChemScene
Product number
CS-8056
Product name
Tradipitant
Purity
99.63%
Packaging
10mg
Price
$250
Updated
2021/12/16
Crysdot
Product number
CD11087683
Product name
Tradipitant
Purity
97%
Packaging
100mg
Price
$602
Updated
2021/12/16
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Tradipitant Chemical Properties,Usage,Production

Uses

Tradipitant, is a neurokinin-1 (NK-1) antagonist.

in vivo

Autoradiography experiments reveal that intravenously administered Tradipitant ([3H]-LY686017) localizes in the guinea pig brain and has a distribution similar to that described for the NK-1 receptor using agonist or antagonist radioligands[1].

Tradipitant Preparation Products And Raw materials

Raw materials

Preparation Products

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Tradipitant Suppliers

China 54 United States 3 Global 57
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32435
Advantage
58
Aladdin Scientific
Tel
Email
tp@aladdinsci.com
Country
United States
ProdList
52923
Advantage
58
Matrix Scientific
Tel
--
Fax
--
Email
sales@matrixscientific.com
Country
United States
ProdList
6632
Advantage
80

622370-35-8, TradipitantRelated Search:


  • Biafungin
  • Tradipitant
  • tradipitant,VLY-686, LY686017
  • [2-[1-[[3,5-bis(trifluoromethyl)phenyl]methyl]-5-(4-pyridinyl)-1H-1,2,3-triazol-4-yl]-3-pyridinyl](2-chlorophenyl)methanone
  • VLY 686
  • LY686017
  • VLY-686;LY686017
  • Tradipitant(VLY-686)
  • (2-(1-(3,5-Bis(trifluoromethyl)benzyl)-5-(pyridin-4-yl)-1H-1,2,3-triazol-4-yl)pyridin-3-yl)(2-
  • Methanone, [2-[1-[[3,5-bis(trifluoromethyl)phenyl]methyl]-5-(4-pyridinyl)-1H-1,2,3-triazol-4-yl]-3-pyridinyl](2-chlorophenyl)-
  • VLY 686,LY-686017,Neurokinin Receptor,VLY686,LY 686017,Inhibitor,Tradipitant,NK receptor,Tachykinin receptor,inhibit
  • (2-(1-(3,5-Bis(trifluoromethyl)benzyl)-5-(pyridin-4-yl)-1H-1,2,3-triazol-4-yl)pyridin-3-yl)(2-chlorophenyl)methanone
  • Tradipitant, 10 mM in DMSO
  • (2-(1-(3,5-Bis(trifluoromethyl)benzyl)-5-(pyridin-4-yl)-1H-1,2,3-triazol-4-yl)pyridin-3-yl)(2-chlorophenyl)methanone?, Tradipitant
  • 622370-35-8
  • C28H16ClF6N5O