EMD 270179

Product Name: EMD 270179
CAS No.: 197172-76-2
Chemical Name: EMD 270179
Synonyms: EMD 270179;Cyclopeptide-5;RonaCare Cyclopeptide 5;Cyclotetrapeptide-24 Aminocyclohexane;Cyclotetrapeptide-24 aminocyclohexane carboxylate;Cyclopeptide-5/CycloTetrapeptide-24 AminocyclohexaneCarboxylate;Cyclo(1-aminocyclohexanecarbonyl-L-arginylglycyl-L-α-aspartyl-D-phenylalanyl);Cyclo(1-aminocyclohexanecarbonyl-L-arginylglycyl-L-alpha-aspartyl-D-phenylalanyl);2-((9R,12S,18S)-9-Benzyl-18-(3-guanidinopropyl)-8,11,14,17,20-pentaoxo-7,10,13,16,19-pentaazaspiro[5.14]icosan-12-yl)acetic acid
CBNumber: CB43052037
Molecular Formula: C28H40N8O7
Formula Weight: 600.67
MOL File: 197172-76-2.mol

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EMD 270179 Property

Density: 1.48±0.1 g/cm3(Predicted)
pka: 4.00±0.10(Predicted)

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Hazard and Precautionary Statements (GHS)

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EMD 270179 Chemical Properties,Usage,Production

Uses

Cyclopeptide-5 (EMD 270179) is an αvβ3 antagonist that can improve PAF-induced increased adhesion of sickle red blood cells, capillary post-obstruction, and enhance blood flow dynamics. Cyclopeptide-5 also has cytotoxic effects[1][2].

References

[1] M Abo-Ghalia, et al. Synthesis and investigation of a new cyclo (Nalpha-dipicolinoyl) pentapeptide of a breast and CNS cytotoxic activity and an ionophoric specificity. Amino Acids. 2004 Jun;26(3):283-9. DOI:10.1007/s00726-003-0042-8
[2] Eileen M Finnegan, et al. Small-molecule cyclic alpha V beta 3 antagonists inhibit sickle red cell adhesion to vascular endothelium and vasoocclusion. Am J Physiol Heart Circ Physiol. 2007 Aug;293(2):H1038-45. DOI:10.1152/ajpheart.01054.2006

EMD 270179 Preparation Products And Raw materials

Raw materials

Preparation Products

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EMD 270179 Suppliers

China 20 United States 1 Global 21

Nanjing Leon Biological Technology Co., Ltd.

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View Lastest Price from EMD 270179 manufacturers

zhuzhou dingcheng meihei comestic co.,ltd

Product: Cyclopeptide-5/CycloTetrapeptide-24 AminocyclohexaneCarboxylate 197172-76-2
Price: US $30.00/Box
Min. Order: 1Box
Purity: 99.99%
Supply Ability: 10000000000
Release date: 2023-12-07

Shanghai Getian Industrial Co., LTD

Product: EMD 270179 197172-76-2
Price: US $28.00-23.00/box
Min. Order: 1box
Purity: 99%
Supply Ability: 20000
Release date: 2024-06-05

197172-76-2, EMD 270179Related Search:

H-CYS-SER-CYS-LYS-ASP-MET-THR-ASP-LYS-GLU-CYS-LEU-ASN-PHE-CYS-HIS-GLN-ASP-VAL-ILE-TRP-OH Hexapeptide-50 Oligopeptide-67 HIV PROTEASE SUBSTRATE VI Octapeptide-12 Acetyl heptapeptide-9 Oligopeptide-27 Dipeptide-10 Myristoyl Tetrapeptide-34 Aminobutyroyl tripeptide-1

Cyclo(1-aminocyclohexanecarbonyl-L-arginylglycyl-L-alpha-aspartyl-D-phenylalanyl)

Cyclopeptide-5

EMD 270179

RonaCare Cyclopeptide 5

Cyclotetrapeptide-24 aminocyclohexane carboxylate

Cyclopeptide-5/CycloTetrapeptide-24 AminocyclohexaneCarboxylate

Cyclo(1-aminocyclohexanecarbonyl-L-arginylglycyl-L-α-aspartyl-D-phenylalanyl)

2-((9R,12S,18S)-9-Benzyl-18-(3-guanidinopropyl)-8,11,14,17,20-pentaoxo-7,10,13,16,19-pentaazaspiro[5.14]icosan-12-yl)acetic acid

Cyclotetrapeptide-24 Aminocyclohexane

197172-76-2

C28H40N8O7