ChemicalBook > CAS DataBase List > EMD 270179
EMD 270179
- Product Name
- EMD 270179
- CAS No.
- 197172-76-2
- Chemical Name
- EMD 270179
- Synonyms
- EMD 270179;Cyclopeptide-5;RonaCare Cyclopeptide 5;Cyclotetrapeptide-24 Aminocyclohexane;Cyclotetrapeptide-24 aminocyclohexane carboxylate;Cyclopeptide-5/CycloTetrapeptide-24 AminocyclohexaneCarboxylate;Cyclo(1-aminocyclohexanecarbonyl-L-arginylglycyl-L-α-aspartyl-D-phenylalanyl);Cyclo(1-aminocyclohexanecarbonyl-L-arginylglycyl-L-alpha-aspartyl-D-phenylalanyl);2-((9R,12S,18S)-9-Benzyl-18-(3-guanidinopropyl)-8,11,14,17,20-pentaoxo-7,10,13,16,19-pentaazaspiro[5.14]icosan-12-yl)acetic acid
- CBNumber
- CB43052037
- Molecular Formula
- C28H40N8O7
- Formula Weight
- 600.67
- MOL File
- 197172-76-2.mol
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EMD 270179 Property
- Density
- 1.48±0.1 g/cm3(Predicted)
- pka
- 4.00±0.10(Predicted)
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EMD 270179 Chemical Properties,Usage,Production
Uses
Cyclopeptide-5 (EMD 270179) is an αvβ3 antagonist that can improve PAF-induced increased adhesion of sickle red blood cells, capillary post-obstruction, and enhance blood flow dynamics. Cyclopeptide-5 also has cytotoxic effects[1][2].
References
[1] M Abo-Ghalia, et al. Synthesis and investigation of a new cyclo (Nalpha-dipicolinoyl) pentapeptide of a breast and CNS cytotoxic activity and an ionophoric specificity. Amino Acids. 2004 Jun;26(3):283-9. DOI:10.1007/s00726-003-0042-8
[2] Eileen M Finnegan, et al. Small-molecule cyclic alpha V beta 3 antagonists inhibit sickle red cell adhesion to vascular endothelium and vasoocclusion. Am J Physiol Heart Circ Physiol. 2007 Aug;293(2):H1038-45. DOI:10.1152/ajpheart.01054.2006
EMD 270179 Preparation Products And Raw materials
Raw materials
Preparation Products
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EMD 270179 Suppliers
- Tel
- 1-631-485-4226; 16314854226
- info@bocsci.com
- Country
- United States
- ProdList
- 12952
- Advantage
- 65
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View Lastest Price from EMD 270179 manufacturers
zhuzhou dingcheng meihei comestic co.,ltd
- Product
- Cyclopeptide-5/CycloTetrapeptide-24 AminocyclohexaneCarboxylate 197172-76-2
- Price
- US $30.00/Box
- Min. Order
- 1Box
- Purity
- 99.99%
- Supply Ability
- 10000000000
- Release date
- 2023-12-07
Shanghai Getian Industrial Co., LTD
- Product
- EMD 270179 197172-76-2
- Price
- US $28.00-23.00/box
- Min. Order
- 1box
- Purity
- 99%
- Supply Ability
- 20000
- Release date
- 2024-06-05
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