2-ETHYNYL-5-FLUOROPYRIDINE

Product Name: 2-ETHYNYL-5-FLUOROPYRIDINE
CAS No.: 884494-34-2
Chemical Name: 2-ETHYNYL-5-FLUOROPYRIDINE
Synonyms: 2-ETHYNYL-5-FLUOROPYRIDINE;Pyridine, 2-ethynyl-5-fluoro-
CBNumber: CB4317108
Molecular Formula: C7H4FN
Formula Weight: 121.11
MOL File: 884494-34-2.mol

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2-ETHYNYL-5-FLUOROPYRIDINE Property

Boiling point:: 150.6±25.0 °C(Predicted)
Density: 1.15±0.1 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
pka: -0.16±0.22(Predicted)
Appearance: Off-white to light yellow Solid
InChI: InChI=1S/C7H4FN/c1-2-7-4-3-6(8)5-9-7/h1,3-5H
InChIKey: KHCIVRLMGQEZPB-UHFFFAOYSA-N
SMILES: C1(C#C)=NC=C(F)C=C1

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC

Product number: B126138
Product name: 2-ethynyl-5-fluoropyridine
Packaging: 100mg
Price: $65
Updated: 2021/12/16

TRC

Product number: B126138
Product name: 2-ethynyl-5-fluoropyridine
Packaging: 500mg
Price: $265
Updated: 2021/12/16

Activate Scientific

Product number: AS47553
Product name: 2-Ethynyl-5-fluoropyridine
Purity: 95+%
Packaging: 1g
Price: $258
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0319605
Product name: 2-ETHYNYL-5-FLUOROPYRIDINE
Purity: 95.00%
Packaging: 1G
Price: $286.65
Updated: 2021/12/16

Activate Scientific

Product number: AS47553
Product name: 2-Ethynyl-5-fluoropyridine
Purity: 95+%
Packaging: 5G
Price: $712
Updated: 2021/12/16

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2-ETHYNYL-5-FLUOROPYRIDINE Chemical Properties,Usage,Production

Synthesis

31181-88-1

90965-06-3

884494-34-2

a) Synthesis of 2-ethynyl-5-fluoropyridine: 5-fluoro-2-formylpyridine (1.10 g, 9.0 mmol) was dissolved in methanol (38 mL), potassium carbonate (2.44 g, 0.018 mol) was added followed by the slow dropwise addition of a solution of dimethyl (1-diazido-2-oxopropyl)phosphonate (2.03 g, 11 mmol) in methanol (12 mL). The reaction mixture was stirred at room temperature for 90 minutes. After completion of the reaction, the mixture was extracted with diethyl ether. The organic layers were combined, washed sequentially with 1 M sodium bicarbonate solution and saturated brine, dried over anhydrous sodium sulfate, filtered, and concentrated under reduced pressure at 0 °C to give a light brown liquid 2-alkynyl-5-fluoropyridine (1.01 g, 78% yield). Mass spectrum (MS): m/e = 121.0 [M]+.

References

[1] Patent: US2012/115844, 2012, A1. Location in patent: Page/Page column 23-24
[2] Patent: WO2012/62687, 2012, A1. Location in patent: Page/Page column 51

2-ETHYNYL-5-FLUOROPYRIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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2-ETHYNYL-5-FLUOROPYRIDINE Suppliers

China 30 India 1 United States 6 Global 37

Pure Chemistry Scientific Inc.

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884494-34-2, 2-ETHYNYL-5-FLUOROPYRIDINERelated Search:

2-ETHYNYL-5-FLUOROPYRIDINE

Pyridine, 2-ethynyl-5-fluoro-

884494-34-2

Fluorine series