PhiKan 083 hydrochloride

Product Name: PhiKan 083 hydrochloride
CAS No.: 1050480-30-2
Chemical Name: PhiKan 083 hydrochloride
Synonyms: PhiKan 083 HCl;PhiKan083 hydrochloride >=98% (HPLC);1-(9-Ethyl-9H-carbazol-3-yl)-N-methylmethanamine hydrochloride
CBNumber: CB43411342
Molecular Formula: C16H19ClN2
Formula Weight: 274.79
MOL File: 1050480-30-2.mol

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PhiKan 083 hydrochloride Property

storage temp.: Store at -20°C
solubility: Soluble to 50 mM in water and to 100 mM in DMSO
form: Solid
color: White to off-white
Water Solubility: Water: 2 mg/mL (7.28 mM and warming)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML1770
Product name: PhiKan083 hydrochloride
Purity: ≥98% (HPLC)
Packaging: 5MG
Price: $87.6
Updated: 2025/07/31

Sigma-Aldrich

Product number: SML1770
Product name: PhiKan083 hydrochloride
Purity: ≥98% (HPLC)
Packaging: 25MG
Price: $354
Updated: 2025/07/31

TRC

Product number: P338500
Product name: PhiKan-083Hydrochloride
Packaging: 10mg
Price: $155
Updated: 2021/12/16

TRC

Product number: P338500
Product name: PhiKan-083Hydrochloride
Packaging: 100mg
Price: $1230
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0123447
Product name: N-[(9-ETHYL-9H-CARBAZOL-3-YL)METHYL]-N-METHYLAMINE HYDROCHLORIDE
Purity: 95.00%
Packaging: 1G
Price: $808.89
Updated: 2021/12/16

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PhiKan 083 hydrochloride Chemical Properties,Usage,Production

Uses

PhiKan-083 is a p53 stabilizing agent. PhiKan-083 preferentially binds mutated (Y220C) p53 over wild-type p53 at a site distinct from functional DNA/protein interaction regions. PhiKan-083 slows rate of thermal denaturation of p53-Y220C.

Biological Activity

PhiKan083 is a small molecule th at binds within a cavity on the surface of Y220C-mutated p53. This mutation, which is not involved in DNA interaction, causes a destabilization of the protein. PhiKan083 binding acts to stabilize the mutant p53 and slow the rate of denaturation.

storage

Store at +4°C

PhiKan 083 hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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PhiKan 083 hydrochloride Suppliers

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1050480-30-2, PhiKan 083 hydrochlorideRelated Search:

PhiKan083 hydrochloride >=98% (HPLC)

1-(9-Ethyl-9H-carbazol-3-yl)-N-methylmethanamine hydrochloride

PhiKan 083 HCl

1050480-30-2