ChemicalBook > CAS DataBase List > PhiKan 083 hydrochloride
PhiKan 083 hydrochloride
- Product Name
- PhiKan 083 hydrochloride
- CAS No.
- 1050480-30-2
- Chemical Name
- PhiKan 083 hydrochloride
- Synonyms
- PhiKan 083 HCl;PhiKan083 hydrochloride >=98% (HPLC);1-(9-Ethyl-9H-carbazol-3-yl)-N-methylmethanamine hydrochloride
- CBNumber
- CB43411342
- Molecular Formula
- C16H19ClN2
- Formula Weight
- 274.79
- MOL File
- 1050480-30-2.mol
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PhiKan 083 hydrochloride Property
- storage temp.
- Store at -20°C
- solubility
- Soluble to 50 mM in water and to 100 mM in DMSO
- form
- Solid
- color
- White to off-white
- Water Solubility
- Water: 2 mg/mL (7.28 mM and warming)
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- SML1770
- Product name
- PhiKan083 hydrochloride
- Purity
- ≥98% (HPLC)
- Packaging
- 5MG
- Price
- $87.6
- Updated
- 2025/07/31
Sigma-Aldrich
- Product number
- SML1770
- Product name
- PhiKan083 hydrochloride
- Purity
- ≥98% (HPLC)
- Packaging
- 25MG
- Price
- $354
- Updated
- 2025/07/31
TRC
- Product number
- P338500
- Product name
- PhiKan-083Hydrochloride
- Packaging
- 10mg
- Price
- $155
- Updated
- 2021/12/16
TRC
- Product number
- P338500
- Product name
- PhiKan-083Hydrochloride
- Packaging
- 100mg
- Price
- $1230
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- CHM0123447
- Product name
- N-[(9-ETHYL-9H-CARBAZOL-3-YL)METHYL]-N-METHYLAMINE HYDROCHLORIDE
- Purity
- 95.00%
- Packaging
- 5G
- Price
- $1421.65
- Updated
- 2021/12/16
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PhiKan 083 hydrochloride Chemical Properties,Usage,Production
Uses
PhiKan-083 is a p53 stabilizing agent. PhiKan-083 preferentially binds mutated (Y220C) p53 over wild-type p53 at a site distinct from functional DNA/protein interaction regions. PhiKan-083 slows rate of thermal denaturation of p53-Y220C.
Biological Activity
PhiKan083 is a small molecule th at binds within a cavity on the surface of Y220C-mutated p53. This mutation, which is not involved in DNA interaction, causes a destabilization of the protein. PhiKan083 binding acts to stabilize the mutant p53 and slow the rate of denaturation.
storage
Store at +4°C
PhiKan 083 hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
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PhiKan 083 hydrochloride Suppliers
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