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PhiKan 083 hydrochloride

Product Name
PhiKan 083 hydrochloride
CAS No.
1050480-30-2
Chemical Name
PhiKan 083 hydrochloride
Synonyms
PhiKan 083 HCl;PhiKan083 hydrochloride >=98% (HPLC);1-(9-Ethyl-9H-carbazol-3-yl)-N-methylmethanamine hydrochloride
CBNumber
CB43411342
Molecular Formula
C16H19ClN2
Formula Weight
274.79
MOL File
1050480-30-2.mol
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PhiKan 083 hydrochloride Property

storage temp. 
Store at -20°C
solubility 
Soluble to 50 mM in water and to 100 mM in DMSO
form 
Solid
color 
White to off-white
Water Solubility 
Water: 2 mg/mL (7.28 mM and warming)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML1770
Product name
PhiKan083 hydrochloride
Purity
≥98% (HPLC)
Packaging
5MG
Price
$87.6
Updated
2025/07/31
Sigma-Aldrich
Product number
SML1770
Product name
PhiKan083 hydrochloride
Purity
≥98% (HPLC)
Packaging
25MG
Price
$354
Updated
2025/07/31
TRC
Product number
P338500
Product name
PhiKan-083Hydrochloride
Packaging
10mg
Price
$155
Updated
2021/12/16
TRC
Product number
P338500
Product name
PhiKan-083Hydrochloride
Packaging
100mg
Price
$1230
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0123447
Product name
N-[(9-ETHYL-9H-CARBAZOL-3-YL)METHYL]-N-METHYLAMINE HYDROCHLORIDE
Purity
95.00%
Packaging
5G
Price
$1421.65
Updated
2021/12/16
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PhiKan 083 hydrochloride Chemical Properties,Usage,Production

Uses

PhiKan-083 is a p53 stabilizing agent. PhiKan-083 preferentially binds mutated (Y220C) p53 over wild-type p53 at a site distinct from functional DNA/protein interaction regions. PhiKan-083 slows rate of thermal denaturation of p53-Y220C.

Biological Activity

PhiKan083 is a small molecule th at binds within a cavity on the surface of Y220C-mutated p53. This mutation, which is not involved in DNA interaction, causes a destabilization of the protein. PhiKan083 binding acts to stabilize the mutant p53 and slow the rate of denaturation.

storage

Store at +4°C

PhiKan 083 hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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PhiKan 083 hydrochloride Suppliers

Haoyuan Chemexpress Co., Ltd.
Tel
021-58950125
Fax
(86) 21-58955996
Email
info@chemexpress.com
Country
China
ProdList
7552
Advantage
61
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
71826
Advantage
60
Changzhou Hopschain Chemical Co.,Ltd.
Tel
0519-85528066 13775048983
Fax
0519-85528066
Email
sales@hopschem.com
Country
China
ProdList
31553
Advantage
55
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 18892239720
Fax
010-60605840
Email
psaitong@jm-bio.com
Country
China
ProdList
12306
Advantage
58
MQ (shanghai) Pharmaceuticals Co., Ltd.
Tel
13761635123
Fax
1014988033@qq
Email
1014988033@qq.com
Country
China
ProdList
4941
Advantage
55
Fan De(Beijing) Biotechnology Co., Ltd.
Tel
15911056312
Email
liming@bio-fount.com
Country
China
ProdList
9729
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32435
Advantage
58
HANGZHOU CLAP TECHNOLOGY CO.,LTD
Tel
86-571-88216897,88216896 13588875226
Fax
86-571-88216895
Email
sales@hzclap.com
Country
CHINA
ProdList
6312
Advantage
58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11218
Advantage
58
Energy Chemical
Tel
021-58432009 400-005-6266
Fax
021-58436166
Email
marketing1@energy-chemical.com
Country
China
ProdList
44894
Advantage
58

1050480-30-2, PhiKan 083 hydrochlorideRelated Search:


  • PhiKan083 hydrochloride >=98% (HPLC)
  • 1-(9-Ethyl-9H-carbazol-3-yl)-N-methylmethanamine hydrochloride
  • PhiKan 083 HCl
  • 1050480-30-2