ChemicalBook > CAS DataBase List > Thymosin beta 4

Thymosin beta 4

Product Name
Thymosin beta 4
CAS No.
77591-33-4
Chemical Name
Thymosin beta 4
Synonyms
Thymosin β4;Thymosin β4 Acetate;Thymosin β4 Acetate;Thymosin beta4;TB500（Thymosin beta-4）;AC-SER-ASP-LYS-PRO-ASP-MET-ALA-GLU-ILE-GLU-LYS-PHE-ASP-LYS-SER-LYS-LEU-LYS-LYS-THR-GLU-THR-GLN-GLU-LYS-ASN-PRO-LEU-PRO-SER-LYS-GLU-THR-ILE-GLU-GLN-GLU-LYS-GLN-ALA-GLY-GLU-SER-OH;Ac-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-Thr-Ile-Glu-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser-OH acetate salt;Tb4;TB500(5MG);Thymosin-b4
CBNumber
CB4409683
Molecular Formula
C212H350N56O78S
Formula Weight
4963.4408
MOL File
77591-33-4.mol
More
Less

Thymosin beta 4 Property

storage temp. 
Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
Water Solubility 
Water : 50 mg/mL?(10.07 mM;?Need ultrasonic)
InChI
InChI=1S/C212H350N56O78S/c1-16-106(7)166(261-190(323)131(64-75-160(292)293)231-172(305)109(10)228-174(307)134(78-91-347-15)245-196(329)140(98-165(302)303)255-201(334)147-53-39-88-266(147)209(342)135(52-29-38-87-221)250-197(330)139(97-164(300)301)254-198(331)143(100-269)229-113(14)276)204(337)246-129(62-73-158(288)289)187(320)233-118(47-24-33-82-216)179(312)252-137(94-114-42-19-18-20-43-114)194(327)253-138(96-163(298)299)195(328)237-121(50-27-36-85-219)181(314)258-144(101-270)199(332)239-119(48-25-34-83-217)178(311)251-136(92-104(3)4)193(326)236-116(45-22-31-80-214)175(308)235-122(51-28-37-86-220)189(322)263-168(110(11)273)207(340)249-133(66-77-162(296)297)192(325)264-169(111(12)274)206(339)248-126(58-69-152(224)279)184(317)243-128(61-72-157(286)287)186(319)234-120(49-26-35-84-218)180(313)256-142(95-153(225)280)211(344)268-90-40-54-148(268)202(335)257-141(93-105(5)6)210(343)267-89-41-55-149(267)203(336)259-145(102-271)200(333)238-117(46-23-32-81-215)177(310)244-132(65-76-161(294)295)191(324)265-170(112(13)275)208(341)262-167(107(8)17-2)205(338)247-130(63-74-159(290)291)188(321)241-125(57-68-151(223)278)183(316)242-127(60-71-156(284)285)185(318)232-115(44-21-30-79-213)176(309)240-124(56-67-150(222)277)173(306)227-108(9)171(304)226-99-154(281)230-123(59-70-155(282)283)182(315)260-146(103-272)212(345)346/h18-20,42-43,104-112,115-149,166-170,269-275H,16-17,21-41,44-103,213-221H2,1-15H3,(H2,222,277)(H2,223,278)(H2,224,279)(H2,225,280)(H,226,304)(H,227,306)(H,228,307)(H,229,276)(H,230,281)(H,231,305)(H,232,318)(H,233,320)(H,234,319)(H,235,308)(H,236,326)(H,237,328)(H,238,333)(H,239,332)(H,240,309)(H,241,321)(H,242,316)(H,243,317)(H,244,310)(H,245,329)(H,246,337)(H,247,338)(H,248,339)(H,249,340)(H,250,330)(H,251,311)(H,252,312)(H,253,327)(H,254,331)(H,255,334)(H,256,313)(H,257,335)(H,258,314)(H,259,336)(H,260,315)(H,261,323)(H,262,341)(H,263,322)(H,264,325)(H,265,324)(H,282,283)(H,284,285)(H,286,287)(H,288,289)(H,290,291)(H,292,293)(H,294,295)(H,296,297)(H,298,299)(H,300,301)(H,302,303)(H,345,346)/t106-,107-,108-,109-,110+,111+,112+,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,144-,145-,146-,147-,148-,149-,166-,167-,168-,169-,170-/m0/s1
InChIKey
UGPMCIBIHRSCBV-XNBOLLIBSA-N
SMILES
S(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]([H])(C(N([H])[C@]([H])(C(N([H])[C@]([H])(C(N([H])[C@]([H])(C(N([H])[C@]([H])(C(N([H])[C@]([H])(C(N([H])[C@]([H])(C(N([H])[C@]([H])(C(N([H])[C@]([H])(C(N([H])[C@@]([H])(C([H])([H])O[H])C(N([H])[C@@]([H])(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C(N([H])[C@@]([H])(C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C(N([H])[C@@]([H])(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C(N([H])[C@@]([H])(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C(N([H])[C@@]([H])([C@@]([H])(C([H])([H])[H])O[H])C(N([H])[C@@]([H])(C([H])([H])C([H])([H])C(=O)O[H])C(N([H])[C@@]([H])([C@@]([H])(C([H])([H])[H])O[H])C(N([H])[C@@]([H])(C([H])([H])C([H])([H])C(N([H])[H])=O)C(N([H])[C@@]([H])(C([H])([H])C([H])([H])C(=O)O[H])C(N([H])[C@@]([H])(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C(N([H])[C@@]([H])(C([H])([H])C(N([H])[H])=O)C(N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(N([H])[C@@]([H])(C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C(N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(N([H])[C@]([H])(C(N([H])[C@]([H])(C(N([H])[C@]([H])(C(N([H])[C@]([H])(C(N([H])[C@]([H])(C(N([H])[C@]([H])(C(N([H])[C@]([H])(C(N([H])[C@]([H])(C(N([H])[C@]([H])(C(N([H])[C@]([H])(C(N([H])[C@]([H])(C(N([H])C([H])([H])C(N([H])[C@]([H])(C(N([H])[C@]([H])(C(=O)O[H])C([H])([H])O[H])=O)C([H])([H])C([H])([H])C(=O)O[H])=O)=O)C([H])([H])[H])=O)C([H])([H])C([H])([H])C(N([H])[H])=O)=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])=O)C([H])([H])C([H])([H])C(=O)O[H])=O)C([H])([H])C([H])([H])C(N([H])[H])=O)=O)C([H])([H])C([H])([H])C(=O)O[H])=O)[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])=O)[C@@]([H])(C([H])([H])[H])O[H])=O)C([H])([H])C([H])([H])C(=O)O[H])=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])=O)C([H])([H])O[H])=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])=O)C([H])([H])C(=O)O[H])=O)C([H])([H])C1C([H])=C([H])C([H])=C([H])C=1[H])=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])=O)C([H])([H])C([H])([H])C(=O)O[H])=O)[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])=O)C([H])([H])C([H])([H])C(=O)O[H])=O)C([H])([H])[H])=O)N([H])C([C@]([H])(C([H])([H])C(=O)O[H])N([H])C([C@]1([H])C([H])([H])C([H])([H])C([H])([H])N1C([C@]([H])(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])N([H])C([C@]([H])(C([H])([H])C(=O)O[H])N([H])C([C@]([H])(C([H])([H])O[H])N([H])C(C([H])([H])[H])=O)=O)=O)=O)=O)=O
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

Usbiological
Product number
157005
Product name
Thymosin Beta 4
Packaging
10ug
Price
$327
Updated
2021/12/16
Usbiological
Product number
157004
Product name
Thymosin Beta 4
Packaging
10ug
Price
$327
Updated
2021/12/16
Usbiological
Product number
157001
Product name
Thymosin Beta 4
Packaging
10ug
Price
$333
Updated
2021/12/16
Usbiological
Product number
157002
Product name
Thymosin Beta 4
Packaging
10ug
Price
$343
Updated
2021/12/16
Usbiological
Product number
T5225-05B
Product name
Thymosin, beta 4
Packaging
1mg
Price
$375
Updated
2021/12/16
More
Less

Thymosin beta 4 Chemical Properties,Usage,Production

Description

Thymosin β-4 is an endogenous pro-angiogenic, fibroblast-activating peptide that is involved in hormone regulation. Thymosin β-4 also exhibits immunomodulatory and cardioprotective activities. Thymosin β-4 improves would healing in cardiac issue and improves cardiac function in vivo. Thymosin β-4 binds G-actin filaments, preventing actin polymerization.

benefits

Thymosin Beta-4 is a 43-amino-acid peptide that promotes healing throughout the body. It also has anti-inflammatory properties. Found naturally in higher concentrations at injury sites, the water-soluble protein can repair tissue damage and regulate cell migration to a site. It can improve wound healing and repair not only the skin, but also the brain, spinal cord, and heart. Medical professionals consider Thymosin Beta-4 a safe and powerful substance in its natural or synthetic form known as TB-500.
In addition, TB4 has a low molecular weight and doesn’t bind to the extracellular matrix. This enables it to easily travel throughout body tissues, which promotes a faster rate of healing. The peptide travels long distances, so it usually doesn’t have to be injected directly at the injury site. While some believe injecting it closer to an injured area yields better results, clinical evidence suggests otherwise.

Mechanism of action

Recent studies have revealed that the first gene to be upregulated after an injury is a Thymosin beta 4 gene. As the body begins the recovery process,Thymosin beta 4 aids in the creation of new vessels in the injured area, which carry blood, nutrients, and reparative substances to the site. It also has anti-inflammatory properties and works to decrease the amount of inflammatory substances, called cytokines. Inflammation plays a large role in many of the symptoms associated with a number of other conditions (i.e., Lyme disease, CFS, FM, autoimmune diseases, infections, etc.), making the potential impact of Tβ4 quite extensive.

Clinical Use

Thymosin beta 4 has been used in the treatment of HIV, AIDS, Influenza, colds, and various infections. It has been utilized in the management of various inflammatory conditions, as well as part of treatment following a heart attack due to its cardio and neuroprotective effects.

Side effects

Many studies have found that Thymosin beta 4 is a safely consumable peptide. The main side effect of Thymosin beta 4 is related to its anti-apoptotic activity, as it may promote the metastatic potential of tumor cells and enable rapid spread. Additionally, common mild side effects of this peptide include redness and discomfort at joints, and in some cases, it may even cause tiredness, lethargy, and headaches.

Thymosin beta 4 Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

Thymosin beta 4 Suppliers

China 277 Germany 1 India 1 Switzerland 1 United Kingdom 1 United States 13 Global 294
Beijing Zhongshuo Pharmaceutical Technology Development Co., Ltd
Tel
010-53679529 13801208576
Fax
010-64215766
Email
sales.2@chinazhongshuo.com
Country
China
ProdList
97
Advantage
65
Cellmano Biotech Limited
Tel
0551-65326643 18156095617
Fax
0551-65326641
Email
info@cellmano.com
Country
China
ProdList
1011
Advantage
55
Sichuan Jisheng Biopharmaceutical Co.,Ltd.
Tel
+86-0833-2598983 +86-18086877136
Fax
+86-833-2598903
Email
Nyx-peptide@jsjpharm.cn
Country
China
ProdList
306
Advantage
58
Sichuan Taihui Biotechnology Co., Ltd
Tel
028-87189093 18599944286
Email
272503470@qq.com
Country
China
ProdList
110
Advantage
58
Shenzhen JYMed Technology Co., Ltd.
Tel
755-755-26612112 15013529272;
Fax
+86 (755) 8635-0488
Email
jymed@jymedtech.com
Country
China
ProdList
81
Advantage
58
Sichuan Takele Biotechnology Co., Ltd.
Tel
+86-028-64348587 15680781153
Email
sales@takelepeptide.com
Country
China
ProdList
91
Advantage
58
Nanjing Yushengkang Biotechnology Co., Ltd
Tel
13327808530
Email
2670965693@qq.com
Country
China
ProdList
2179
Advantage
58
Chinapeptide
Tel
15295566865 15295566865
Email
glenn@synpeptide.com
Country
China
ProdList
27
Advantage
58
Zhongke Huayao (Jiangsu) Biotechnology Co., Ltd
Tel
18014456767 18014456767
Email
wenxi@jszkhy.com
Country
China
ProdList
1349
Advantage
58
Shanghai Boyle Chemical Co., Ltd.
Tel
Fax
86-21-57758967
Email
sales@boylechem.com
Country
China
ProdList
2923
Advantage
55
More
Less

View Lastest Price from Thymosin beta 4 manufacturers

Wuhan Cell Pharmaceutical Co., Ltd
Product
TB500（Thymosin beta-4）
Price
US $5.00-9.00/mg
Min. Order
1mg
Purity
99%
Supply Ability
1000g
Release date
2023-03-31
Wuhan Cell Pharmaceutical Co., Ltd
Product
Thymosin beta 4 acetate 77591-33-4
Price
US $50.00/g
Min. Order
1g
Purity
99%
Supply Ability
100kg
Release date
2023-04-07
Hebei Kangcang new material Technology Co., LTD
Product
Thymosin beta 4 acetate 77591-33-4
Price
US $9.00-80.00/g
Min. Order
10g
Purity
min99%
Supply Ability
10 tons
Release date
2024-03-26

77591-33-4, Thymosin beta 4Related Search:

Cellulose acetate Benzyl acetate Thymine Ethyl acetate Butyl acetate Magnesium acetate Vinyl acetate Ammonium acetate Goserelin acetate Sodium acetate Thymopentin Thymosin α1 THYMOPENTIN THYMOSIN BETA10 (HUMAN, RAT) Thymalfasin impurity Atosiban Secretin Acetate HOE-140

  • AC-SER-ASP-LYS-PRO-ASP-MET-ALA-GLU-ILE-GLU-LYS-PHE-ASP-LYS-SER-LYS-LEU-LYS-LYS-THR-GLU-THR-GLN-GLU-LYS-ASN-PRO-LEU-PRO-SER-LYS-GLU-THR-ILE-GLU-GLN-GLU-LYS-GLN-ALA-GLY-GLU-SER-OH
  • FX (HUMAN, BOVINE, HORSE, RAT)
  • thymosin beta 4 acetate
  • THYMOSIN BETA4 (HUMAN, BOVINE, HORSE, RAT)
  • Thymosin beta4
  • Thymosin Beta4 Beta4 Acetate
  • Thymosin β4 Acetate
  • THYMOSIN SS4 ACETATE
  • ThyMosin b-4 Acetate
  • ThyMosin b4 (huMan, bovine, horse, rat)
  • Ac-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-Thr-Ile-Glu-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser-OH acetate salt
  • Thymosin β4 Acetate(Thymosin Beta 4 Acetate)
  • beta 4 Thymosin beta 4 acetate
  • TB500(5MG)
  • TB500 77591-33-4
  • Thymosin Beta-4, Sh-Oligopeptide-4, TB500
  • TB500 Thymosin Beta-4 with 2mg / vial for Muscle Gaining CAS NO.77591-33-4 CAS NO.77591-33-4
  • Thymosin Beta-4(TB500)
  • Thymosin beta 4,Thymosin β4, >98%
  • Thymosin β4
  • TB500（Thymosin beta-4）
  • Thymosin?β4?Acetate impurity
  • Bodybuilding lyophilized powder tb500 tb-500 5mg 10mg peptide
  • Thymosin beta 4 acetate USP/EP/BP
  • Thymosin β4 (human, bovine, horse, rat)
  • Thymosin β4 Acetate
  • Thymosin β4(cattle)
  • Thymosin beta 4 acetate、TB-500
  • Thymosin-β4 and its derivatives (TB-500)
  • Ferrocene Impurity 1
  • Tb4
  • Thymosin-b4
  • β4Thymosin β4
  • TB500(Thymosin B4 Acetate）
  • rh-Oligopeptide-4
  • Thymosin beta 4,Thymosin β4
  • 77591-33-4
  • 75591-33-4
  • 477591-33-4
  • 77951-33-4
  • C212H350N56O78S
  • Generic Peptide
  • Peptide
  • 77591-33-4