GNE-6468

Product Name: GNE-6468
CAS No.: 1677668-27-7
Chemical Name: GNE-6468
Synonyms: GNE-6468;GNE 6468,GNE6468;Benzoic acid, 4-[6-(2-chloro-6-cyclopropylbenzoyl)imidazo[1,5-a]pyrimidin-8-yl]-2-hydroxy-
CBNumber: CB44667953
Molecular Formula: C23H16ClN3O4
Formula Weight: 433.84
MOL File: 1677668-27-7.mol

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GNE-6468 Property

Density: 1.55±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO: 5 mg/mL (11.52 mM)
pka: 2.35±0.10(Predicted)
form: Solid
color: Light yellow to yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0016580
Product name: GNE-6468
Purity: 99.50%
Packaging: 5mg
Price: $450
Updated: 2021/12/16

ChemScene

Product number: CS-0016580
Product name: GNE-6468
Purity: 99.50%
Packaging: 10mg
Price: $750
Updated: 2021/12/16

ChemScene

Product number: CS-0016580
Product name: GNE-6468
Purity: 99.50%
Packaging: 50mg
Price: $2250
Updated: 2021/12/16

ChemScene

Product number: CS-0016580
Product name: GNE-6468
Purity: 99.50%
Packaging: 100mg
Price: $3350
Updated: 2021/12/16

ChemScene

Product number: CS-0016580
Product name: GNE-6468
Purity: 99.50%
Packaging: 250mg
Price: $5350
Updated: 2021/12/16

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GNE-6468 Chemical Properties,Usage,Production

Description

GNE-6468 is a potent and selective RORc inverse agonist. GNE-6468 displayed >300-fold selectivity for RORc over the other ROR family members, PPARγ, and NRs in our cellular selectivity panel. The favorable potency, selectivity, and physiochemical properties of GNE-6468, in addition to its potent suppression of IL-17 production in human primary cells, support its use as chemical biology tools to further explore the role of RORc in human biology. The nuclear receptor (NR) retinoic acid receptor-related orphan receptor gamma (RORγ, RORc, or NR1F3) is a promising target for the treatment of autoimmune diseases. RORc is a critical regulator in the production of the pro-inflammatory cytokine interleukin-17.

GNE-6468 Preparation Products And Raw materials

Raw materials

Preparation Products

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GNE-6468 Suppliers

China 7 United States 3 Global 10

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 32161
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ChemeGen(Shanghai) Biotechnology Co.,Ltd.

Tel: 18818260767
Fax: QQ 3610331285
Email: sales@chemegen.com
Country: China
ProdList: 11218
Advantage: 58

Shanghai hongqu biomedical technology co. LTD

Tel: 88888888888
Email: hongquchem@qq.com
Country: China
ProdList: 5132
Advantage: 58

TargetMol Chemicals Inc.

Tel: 4008200310
Email: marketing@tsbiochem.com
Country: China
ProdList: 24644
Advantage: 58

Shanghai Yifei Biotechnology Co. , Ltd.

Tel: 021-65675885 18964387627
Email: customer_service@efebio.com
Country: China
ProdList: 11974
Advantage: 58

Shanghai?Medlife?Pharm-Tech?Co.,?Ltd

Tel: 021-59167510 18117107507
Email: vip@med-life.cn
Country: China
ProdList: 4997
Advantage: 58

RD International Technology Co., Limited

Tel: 18024082417
Email: market@ubiochem.com
Country: China
ProdList: 9266
Advantage: 58

TargetMol Chemicals Inc.

Tel: +8613564774135
Email: zijue.cai@tsbiochem.com
Country: United States
ProdList: 19881
Advantage: 58

Aladdin Scientific

Tel
Email: tp@aladdinsci.com
Country: United States
ProdList: 52924
Advantage: 58

1677668-27-7, GNE-6468Related Search:

GNE-6468

Benzoic acid, 4-[6-(2-chloro-6-cyclopropylbenzoyl)imidazo[1,5-a]pyrimidin-8-yl]-2-hydroxy-

GNE 6468,GNE6468

1677668-27-7