ALLO-2 (Smo inhibitor ALLO-2)

Product Name: ALLO-2 (Smo inhibitor ALLO-2)
CAS No.: 1357350-60-7
Chemical Name: ALLO-2 (Smo inhibitor ALLO-2)
Synonyms: ALLO-2;ALLO-2, 10 mM in DMSO;ALLO-2 (Smo inhibitor ALLO-2);Inhibitor,ALLO-2,inhibit,Smo,ALLO 2,Smoothened,ALLO2;N-(4-(4-(Trifluoromethoxy)phenyl)pyrimidin-2-yl)-1H-indazol-5-amine;1H-Indazol-5-amine, N-[4-[4-(trifluoromethoxy)phenyl]-2-pyrimidinyl]-
CBNumber: CB44844459
Molecular Formula: C18H12F3N5O
Formula Weight: 371.32
MOL File: 1357350-60-7.mol

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ALLO-2 (Smo inhibitor ALLO-2) Property

storage temp.: Store at -20°C
solubility: DMSO : 125 mg/mL (336.64 mM)
form: Solid
color: Light yellow to yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0065882
Product name: ALLO-2
Purity: 99.58%
Packaging: 5mg
Price: $350
Updated: 2021/12/16

ChemScene

Product number: CS-0065882
Product name: ALLO-2
Purity: 99.58%
Packaging: 10mg
Price: $550
Updated: 2021/12/16

ChemScene

Product number: CS-0065882
Product name: ALLO-2
Purity: 99.58%
Packaging: 50mg
Price: $1750
Updated: 2021/12/16

ChemScene

Product number: CS-0065882
Product name: ALLO-2
Purity: 99.58%
Packaging: 100mg
Price: $2750
Updated: 2021/12/16

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ALLO-2 (Smo inhibitor ALLO-2) Chemical Properties,Usage,Production

Uses

ALLO-2 is a potent drug-resistant Smoothened (Smo) mutant antagonist that inhibits Smo agonist Hh-Ag1.5-induced luciferase expression in TM3-Gli-Luc cells with IC50 of 6 nM[1].

References

[1] Tao H, et al. Small molecule antagonists in distinct binding modes inhibit drug-resistant mutant of smoothened. Chem Biol. 2011 Apr 22;18(4):432-7. DOI:10.1016/j.chembiol.2011.01.018

ALLO-2 (Smo inhibitor ALLO-2) Preparation Products And Raw materials

Raw materials

Preparation Products

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1357350-60-7, ALLO-2 (Smo inhibitor ALLO-2)Related Search:

ALLO-2 (Smo inhibitor ALLO-2)

ALLO-2

1H-Indazol-5-amine, N-[4-[4-(trifluoromethoxy)phenyl]-2-pyrimidinyl]-

N-(4-(4-(Trifluoromethoxy)phenyl)pyrimidin-2-yl)-1H-indazol-5-amine

Inhibitor,ALLO-2,inhibit,Smo,ALLO 2,Smoothened,ALLO2

ALLO-2, 10 mM in DMSO

1357350-60-7