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ALLO-2 (Smo inhibitor ALLO-2)

Product Name
ALLO-2 (Smo inhibitor ALLO-2)
CAS No.
1357350-60-7
Chemical Name
ALLO-2 (Smo inhibitor ALLO-2)
Synonyms
ALLO-2;ALLO-2, 10 mM in DMSO;ALLO-2 (Smo inhibitor ALLO-2);Inhibitor,ALLO-2,inhibit,Smo,ALLO 2,Smoothened,ALLO2;N-(4-(4-(Trifluoromethoxy)phenyl)pyrimidin-2-yl)-1H-indazol-5-amine;1H-Indazol-5-amine, N-[4-[4-(trifluoromethoxy)phenyl]-2-pyrimidinyl]-
CBNumber
CB44844459
Molecular Formula
C18H12F3N5O
Formula Weight
371.32
MOL File
1357350-60-7.mol
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ALLO-2 (Smo inhibitor ALLO-2) Property

storage temp. 
Store at -20°C
solubility 
DMSO : 125 mg/mL (336.64 mM)
form 
Solid
color 
Light yellow to yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene
Product number
CS-0065882
Product name
ALLO-2
Purity
99.58%
Packaging
5mg
Price
$350
Updated
2021/12/16
ChemScene
Product number
CS-0065882
Product name
ALLO-2
Purity
99.58%
Packaging
10mg
Price
$550
Updated
2021/12/16
ChemScene
Product number
CS-0065882
Product name
ALLO-2
Purity
99.58%
Packaging
50mg
Price
$1750
Updated
2021/12/16
ChemScene
Product number
CS-0065882
Product name
ALLO-2
Purity
99.58%
Packaging
100mg
Price
$2750
Updated
2021/12/16
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ALLO-2 (Smo inhibitor ALLO-2) Chemical Properties,Usage,Production

Uses

ALLO-2 is a potent drug-resistant Smoothened (Smo) mutant antagonist that inhibits Smo agonist Hh-Ag1.5-induced luciferase expression in TM3-Gli-Luc cells with IC50 of 6 nM[1].

References

[1] Tao H, et al. Small molecule antagonists in distinct binding modes inhibit drug-resistant mutant of smoothened. Chem Biol. 2011 Apr 22;18(4):432-7. DOI:10.1016/j.chembiol.2011.01.018

ALLO-2 (Smo inhibitor ALLO-2) Preparation Products And Raw materials

Raw materials

Preparation Products

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ALLO-2 (Smo inhibitor ALLO-2) Suppliers

China 30 United States 5 Global 35
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32435
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58
InvivoChem
Tel
+1-708-310-1919 +1-13798911105
Fax
708-557-7486
Email
sales@invivochem.cn
Country
United States
ProdList
6391
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354;
Email
support@targetmol.com
Country
United States
ProdList
39035
Advantage
58
Aladdin Scientific
Tel
Email
tp@aladdinsci.com
Country
United States
ProdList
52923
Advantage
58
MedChemExpress
Tel
--
Fax
--
Email
sales@medchemexpress.com
Country
United States
ProdList
6398
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58

1357350-60-7, ALLO-2 (Smo inhibitor ALLO-2)Related Search:


  • ALLO-2 (Smo inhibitor ALLO-2)
  • ALLO-2
  • 1H-Indazol-5-amine, N-[4-[4-(trifluoromethoxy)phenyl]-2-pyrimidinyl]-
  • N-(4-(4-(Trifluoromethoxy)phenyl)pyrimidin-2-yl)-1H-indazol-5-amine
  • Inhibitor,ALLO-2,inhibit,Smo,ALLO 2,Smoothened,ALLO2
  • ALLO-2, 10 mM in DMSO
  • 1357350-60-7