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Nicarbazin

Product Name
Nicarbazin
CAS No.
330-95-0
Chemical Name
Nicarbazin
Synonyms
NICARBAZINE;mk75;nicarb;nicoxin;nirazin;nicrazin;Nicarzin;nicrazine;nicarbazi;CB4734477
CBNumber
CB4734477
Molecular Formula
C19H18N6O6
Formula Weight
426.38
MOL File
330-95-0.mol
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Nicarbazin Property

Melting point:
265-267 °C
Boiling point:
541.86°C (rough estimate)
Density 
1.4663 (rough estimate)
refractive index 
1.6000 (estimate)
storage temp. 
0-6°C
solubility 
DMSO: soluble0.5mg/mL
color 
Yellow to Dark Yellow
EPA Substance Registry System
Nicarbazin (330-95-0)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
RTECS 
FE0900000
HS Code 
38249099
Hazardous Substances Data
330-95-0(Hazardous Substances Data)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
N3905
Product name
Nicarbazin
Packaging
100g
Price
$67.8
Updated
2024/03/01
Sigma-Aldrich
Product number
32409
Product name
Nicarbazin
Purity
VETRANAL?, analytical standard
Packaging
100mg
Price
$155
Updated
2024/03/01
TRC
Product number
N394530
Product name
Nicarbazine
Packaging
10g
Price
$425
Updated
2021/12/16
Usbiological
Product number
N2515-02
Product name
Nicarbazin
Packaging
500ul
Price
$814
Updated
2021/12/16
AK Scientific
Product number
J11499
Product name
Nicarbazine
Packaging
25mg
Price
$58
Updated
2021/12/16
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Nicarbazin Chemical Properties,Usage,Production

Chemical Properties

Nicarbazin is a light yellow crystalline powder, odorless. Melting point 265-275°C (decomposition). Non-hygroscopic, insoluble in water, ethanol, chloroform and ether, slightly soluble in dimethylformamide. It decomposes slowly when it is ground with water, and decomposes faster in dilute acid.

Uses

Nicarbazin, is a coccidiostat, which is an antiprotozoal agent that acts upon Coccidia parasites.It is a contraceptive for resident Canada geese and waterfowl. It is used to study avian reproduction and is used to interfere with the formation of the vitelline (yolk) membrane in bird eggs. It has been used to study how delivery method can effect plasma levels of 4,4′-dinitrocarbanilide (DNC), which is the active anticoccidial component of Nicarbazin.

Definition

ChEBI: Nicarbazin is an organic molecular entity. It is an equimolar complex of 4,4'-Dinitrocarbanilide and 2-Hydroxy-4,6-dimethylpyrimidine. A coccidiostat for poultry.

Biochem/physiol Actions

Nicarbazin, an effective anticoccidial, is also a wide-spectrum anti-parasitic drug. It affects avian reproduction by reducing egg production, egg weight, and egg hatchability. The mechanism of action of Nicarbazin is unknown.

Mode of action

Nicarbazin interferes with the formation of the vitelline membrane, separating the egg yolk and egg white. The exact mode of action is unknown, although it is thought nicarbazin interferes with cholesterol metabolism in the formation of the membrane. Eggs from treated birds are described as mottled in appearance, reflecting a porous vitelline membrane. The effect on hatchability is a function of time and dose and the effect is reversible.

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View Lastest Price from Nicarbazin manufacturers

Shaanxi TNJONE Pharmaceutical Co., Ltd
Product
Nicarbazin 330-95-0
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1000kg
Release date
2024-04-07
WUHAN CIRCLE POWDER TECHNOLOGY CO.,LTD
Product
Nicarbazin 330-95-0
Price
US $0.00/KG
Min. Order
100g
Purity
98%+
Supply Ability
100kg
Release date
2020-10-14
shandong perfect biotechnology co.ltd
Product
Nicarbazin 330-95-0
Price
US $0.00/kg
Min. Order
1kg
Purity
70%
Supply Ability
10Tons
Release date
2024-02-20

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