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Eplivanserin

Product Name
Eplivanserin
CAS No.
130579-75-8
Chemical Name
Eplivanserin
Synonyms
EPLIVANSERIN;VAIOZOCLKVMIMN-PRJWTAEASA-N;Eplivanserin, 10 mM in DMSO;(Z,E)-1-(2-Fluorophenyl)-3-(4-hydroxyphenyl)-2-propen-1-one O-[2-(dimethylamino)ethyl]oxime;2-Propen-1-one, 1-(2-fluorophenyl)-3-(4-hydroxyphenyl)-, O-[2-(dimethylamino)ethyl]oxime, (1Z,2E)-;5-hydroxytryptamine Receptor,Serotonin Receptor,5-HT2A,5-HT Receptor,Eplivanserin,SR46349,oral,dopamine,SR 46349,Inhibitor,inhibit,release
CBNumber
CB51011732
Molecular Formula
C19H21FN2O2
Formula Weight
328.38
MOL File
130579-75-8.mol
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Eplivanserin Property

Boiling point:
453.4±55.0 °C(Predicted)
Density 
1.08
storage temp. 
Store at -20°C
solubility 
Soluble in DMSO
pka
9.60±0.15(Predicted)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P273Avoid release to the environment.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P391Collect spillage. Hazardous to the aquatic environment

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
HCH0136821
Product name
(E)-1-(2-FLUOROPHENYL)-3-(4-HYDROXYPHENYL)-2-PROPEN-1-ONE O-[2-(DIMETHYLAMINO)ETHYL]OXIME
Purity
95.00%
Packaging
5MG
Price
$504.44
Updated
2021/12/16
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Eplivanserin Chemical Properties,Usage,Production

Uses

Eplivanserin is used in the treatment of dystonia.

in vivo

Eplivanserin hemifumarate (SR 46349B) inhibits 5-HT2 receptor binding of [3H]ketanserin with an ED50 of 0.087 mg/kg after i.p. injection, and 0.097 mg/kg after p.o administration in mice[1].
SR 46349B (0.25-1 mg/kg; i.p.) blocks Cocaine-evoked hyperactivity following repeated Cocaine treatment in rats[2].

IC 50

5-HT2A Receptor: 5.8 nM (IC50, in rat cortical membrane); 5-HT2A Receptor: 1.14 nM (Ki); 5-HT2C Receptor: 120 nM (IC50)

Eplivanserin Preparation Products And Raw materials

Raw materials

Preparation Products

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Eplivanserin Suppliers

China 25 South Korea 1 The Netherlands 1 United States 4 Global 31
LGM Pharma
Tel
1-(800)-881-8210
Fax
615-250-9817
Email
inquiries@lgmpharma.com
Country
United States
ProdList
2123
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70
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32435
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354;
Email
support@targetmol.com
Country
United States
ProdList
39035
Advantage
58
MedChemExpress
Tel
--
Fax
--
Email
sales@medchemexpress.com
Country
United States
ProdList
6398
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58

130579-75-8, EplivanserinRelated Search:

Mianserin hydrochloride PROPYLENE Chlorodimethylphenylsilane 4-[[4-[[4-[(E)-2-cyanoethenyl]-2,6-dimethyl-phenyl]amino]pyrimidin-2-yl]amino]benzonitrile 1-Hydroxyethylidene-1,1-diphosphonic acid Mianserin Hydroxyphenyl 4-PHENYLBUT-3-EN-2-ONE OXIME EPLIVANSERIN FUMARATE Eplivanserin

  • VAIOZOCLKVMIMN-PRJWTAEASA-N
  • EPLIVANSERIN
  • (Z,E)-1-(2-Fluorophenyl)-3-(4-hydroxyphenyl)-2-propen-1-one O-[2-(dimethylamino)ethyl]oxime
  • 5-hydroxytryptamine Receptor,Serotonin Receptor,5-HT2A,5-HT Receptor,Eplivanserin,SR46349,oral,dopamine,SR 46349,Inhibitor,inhibit,release
  • 2-Propen-1-one, 1-(2-fluorophenyl)-3-(4-hydroxyphenyl)-, O-[2-(dimethylamino)ethyl]oxime, (1Z,2E)-
  • Eplivanserin, 10 mM in DMSO
  • 130579-75-8