2-Chloromethylbenzimidazole

Product Name: 2-Chloromethylbenzimidazole
CAS No.: 4857-04-9
Chemical Name: 2-Chloromethylbenzimidazole
Synonyms: 2-(chloroMethyl)-1H-benzo[d]iMidazole;2-(CHLOROMETHYL)BENZIMIDAZOLE;TIMTEC-BB S;AKOS BBS-00003999;TIMTEC-BB SBB001845;ASINEX-REAG BAS 05306272;CHLOROMETHYLBENZIMIDAZOLE;2-Chloromethylbenzimidazole,95%;2-CHLOROMETHYL-1H-BENZOIMIDAZOLE;2-(CHLOROMETHYL)-1H-BENZIMIDAZOLE
CBNumber: CB5128718
Molecular Formula: C8H7ClN2
Formula Weight: 166.61
MOL File: 4857-04-9.mol

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2-Chloromethylbenzimidazole Property

Melting point:: 146-148 °C (dec.)(lit.)
Boiling point:: 274.83°C (rough estimate)
Density: 1.2387 (rough estimate)
refractive index: 1.5500 (estimate)
storage temp.: Storage temp. -20°C
pka: 11.18±0.10(Predicted)
form: Powder
color: Beige to dark yellow
Water Solubility: Insoluble in water.
InChI: InChI=1S/C8H7ClN2/c9-5-8-10-6-3-1-2-4-7(6)11-8/h1-4H,5H2,(H,10,11)
InChIKey: SPMLMLQATWNZEE-UHFFFAOYSA-N
SMILES: C1(CCl)NC2=CC=CC=C2N=1
CAS DataBase Reference: 4857-04-9(CAS DataBase Reference)

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Safety

Hazard Codes: Xn,Xi
Risk Statements: 22-36/37/38
Safety Statements: 26-37/39-36
WGK Germany: 3
HazardClass: IRRITANT
HS Code: 29339900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: C52055
Product name: 2-(Chloromethyl)benzimidazole
Purity: 96%
Packaging: 5g
Price: $55.8
Updated: 2025/07/31

Sigma-Aldrich

Product number: C52055
Product name: 2-(Chloromethyl)benzimidazole
Purity: 96%
Packaging: 25g
Price: $60.5
Updated: 2025/07/31

Biosynth Carbosynth

Product number: FC03143
Product name: 2-Chloromethyl benzimidazole
Packaging: 10g
Price: $150
Updated: 2021/12/16

Matrix Scientific

Product number: 018702
Product name: 2-(Chloromethyl)-1H-1,3-benzimidazole
Packaging: 5g
Price: $62
Updated: 2021/12/16

AK Scientific

Product number: J95938
Product name: 2-Chloromethylbenzimidazole
Packaging: 25g
Price: $60
Updated: 2021/12/16

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2-Chloromethylbenzimidazole Chemical Properties,Usage,Production

Chemical Properties

beige to dark yellow powder

Uses

2-(Chloromethyl)benzimidazole is used as intermediate in pharmaceutical , in organic synthesis .

Synthesis

79-11-8

95-54-5

4857-04-9

GENERAL METHOD: A mixture of o-phenylenediamine (0.1 mol) and chloroacetic acid (0.15 mol) in 100 mL of 5N HCl was heated to reflux and stirred continuously for 3-5 hours. Upon completion of the reaction, the mixture was cooled to room temperature and subsequently neutralized with sodium bicarbonate solution. The precipitate of 2-chloromethylbenzimidazole formed was collected by filtration, washed several times with water and finally dried to obtain the pure product.

References

[1] Collection of Czechoslovak Chemical Communications, 1991, vol. 56, # 6, p. 1358 - 1360
[2] Revue Roumaine de Chimie, 2016, vol. 61, # 1, p. 15 - 22
[3] Oriental Journal of Chemistry, 2017, vol. 33, # 6, p. 3138 - 3143
[4] Heterocycles, 2002, vol. 57, # 8, p. 1423 - 1432
[5] Journal of the Korean Chemical Society, 2010, vol. 54, # 5, p. 589 - 593

2-Chloromethylbenzimidazole Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 2-Chloromethylbenzimidazole manufacturers

PUSHAN INDUSTRIAL (SHAANXI) CO.,LTD

Product: 2-Chloromethylbenzimidazole 4857-04-9
Price: US $0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 500 kgs
Release date: 2024-07-08

Zhuozhou Wenxi import and Export Co., Ltd

Product: 2-Chloromethylbenzimidazole 4857-04-9
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-06-27

Career Henan Chemical Co

Product: 2-Chloromethylbenzimidazole 4857-04-9
Price: US $8.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10tons
Release date: 2018-12-23

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C8H7N2Cl

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