ChemicalBook > CAS DataBase List > 5-Fluoro-1,3-isobenzofurandione

5-Fluoro-1,3-isobenzofurandione

Product Name
5-Fluoro-1,3-isobenzofurandione
CAS No.
319-03-9
Chemical Name
5-Fluoro-1,3-isobenzofurandione
Synonyms
4-FLUOROPHTHALIC ANHYDRIDE;4-FPA;4-Fluorophthalic;4-Fluorophthalicanhydride97%;4-FluorophthalicAnhydride>5-fluoro-3-isobenzofurandione;4-Fluorophthalicanhydride,98%;4-Fluor-phthalsaeure-anhydrid;4-Fluorophthalic anhydride 97%;4-Fluorophthalic anhydride,99%
CBNumber
CB5204430
Molecular Formula
C8H3FO3
Formula Weight
166.11
MOL File
319-03-9.mol
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5-Fluoro-1,3-isobenzofurandione Property

Melting point:
75-79 °C (lit.)
Boiling point:
148°C 20mm
Density 
1.55
Flash point:
>93°C
storage temp. 
Inert atmosphere,Store in freezer, under -20°C
solubility 
Soluble in sodium hydroxide.
form 
powder to crystal
color 
White to Almost white
Sensitive 
Moisture Sensitive
BRN 
131281
InChI
InChI=1S/C8H3FO3/c9-4-1-2-5-6(3-4)8(11)12-7(5)10/h1-3H
InChIKey
XVMKZAAFVWXIII-UHFFFAOYSA-N
SMILES
C1(=O)C2=C(C=C(F)C=C2)C(=O)O1
CAS DataBase Reference
319-03-9(CAS DataBase Reference)
EPA Substance Registry System
1,3-Isobenzofurandione, 5-fluoro- (319-03-9)
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Safety

Hazard Codes 
Xn,Xi
Risk Statements 
22-36/37/38-42/43
Safety Statements 
26-36/37/39-45
RIDADR 
UN 2811 6.1/PG 3
WGK Germany 
2
Hazard Note 
Irritant
TSCA 
Yes
HazardClass 
IRRITANT, MOISTURE SENSITIVE
PackingGroup 
Ⅲ
HS Code 
29173990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
641375
Product name
4-Fluorophthalic anhydride
Purity
97%
Packaging
5g
Price
$79.8
Updated
2025/07/31
Sigma-Aldrich
Product number
641375
Product name
4-Fluorophthalic anhydride
Purity
97%
Packaging
25g
Price
$312.9
Updated
2025/07/31
TCI Chemical
Product number
F0322
Product name
4-Fluorophthalic Anhydride
Purity
>98.0%(GC)
Packaging
5g
Price
$114
Updated
2025/07/31
Matrix Scientific
Product number
004031
Product name
4-Fluorophthalic anhydride
Purity
97%
Packaging
5g
Price
$37
Updated
2021/12/16
AK Scientific
Product number
J56120
Product name
4-Fluorophthalic Anhydride
Packaging
1g
Price
$39
Updated
2021/12/16
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5-Fluoro-1,3-isobenzofurandione Chemical Properties,Usage,Production

Chemical Properties

white to light yellow crystal powder

Uses

4-Fluorophthalic anhydride is used in the preparation of 5-fluoro-2-pyridin-3-ylmethyl-isoindole-1,3-dione by reacting with C-pyridin-3-yl-methylamine.

Uses

4-Fluorophthalic anhydride can be used as a reactant to prepare:

  • 4-amino substituted phthalimides applicable as potential fluorescent probes and fluorescent bioactive compounds.
  • 4,4′-bis(4-fluorophthalimido)diphenyl ether monomer, which is used in the synthesis of cardo polymers via nucleophilic substitution polymerization reaction.
  • Asymmetric polyimides by a solution polycondensation reaction.

General Description

4-Fluorophthalic anhydride is a fluorinated building block commonly used in chemical synthesis for the preparation of polyimide, pesticides, herbicides, and fungicides. It can be synthesized by treating 4-chlorophthalic anhydride with potassium fluoride.

5-Fluoro-1,3-isobenzofurandione Preparation Products And Raw materials

Raw materials

Preparation Products

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5-Fluoro-1,3-isobenzofurandione Suppliers

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View Lastest Price from 5-Fluoro-1,3-isobenzofurandione manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
Product
4-Fluorophthalic anhydride 319-03-9
Price
US $2.20-8.80/kg
Min. Order
1kg
Purity
99%
Supply Ability
100kg
Release date
2025-06-17
Longyan Tianhua Biological Technology Co., Ltd
Product
5-Fluoro-1,3-isobenzofurandione 319-03-9
Price
US $150.00/Kg/Bag
Min. Order
25Kg/Bag
Purity
99%
Supply Ability
20 Tons
Release date
2020-11-13
Career Henan Chemical Co
Product
5-Fluoro-1,3-isobenzofurandione 319-03-9
Price
US $1.00/KG
Min. Order
1g
Purity
99.0%
Supply Ability
100kg
Release date
2020-01-10

319-03-9, 5-Fluoro-1,3-isobenzofurandioneRelated Search:

Phthalic acid 3-Nitrophthalic anhydride Phthalic anhydride Biphenyl-4,4'-dicarboxylic acid 4-Fluoro-1,1'-biphenyl 4-Fluorophthalic acid 4-Fluoro-1,3-isobenzofurandione 3,6-DIFLUOROPHTHALIC ANHYDRIDE AKOS 92366 5-Fluoro-1,3-isobenzofurandione 4,5-DIFLUOROPHTHALIC ANHYDRIDE Tetrafluorophthalic anhydride AKOS 92364

  • 5-fluoro-3-isobenzofurandione
  • 5-Fluoro-isobenzofuran-1,3-dione
  • 5-FLUORO-BENZO[C]FURAN-1,3-DIONE
  • 5-Fluoro-1,3-isobenzofurandione
  • 5-FLUORO-2-BENZOFURAN-1,3-DIONE
  • 4-FLUOROPHTHALIC ACID ANHYDRIDE
  • 4-FLUOROPHTHALIC ANHYDRIDE
  • 4-FLUOROBENZENE-1,2-DICARBOXYLIC ANHYDRIDE
  • 4-Fluorophthalic
  • 4-Fluorophthalic anhydride 97%
  • 4-Fluorophthalicanhydride97%
  • 4-FPA
  • 1,3-Isobenzofurandione, 5-fluoro-
  • 5-fFuoro-2-benzofuran-1,3-dione
  • 4-Fluorophthalic anhydride,99%
  • 4-Fluorophthalicanhydride,98%
  • 4-FLUOROBENZENE-1,2-DICARBOXYLIC ANH
  • 5-Fluoro-2-benzofuran-1,3-dione, 5-Fluorobenzo[c]furan-1,3-dione, 5-Fluoroisobenzofuran-1,3-dione
  • 5-fluoro-1,3-dihydro-2-benzofuran-1,3-dione
  • 4-FluorophthalicAnhydride&gt
  • 4-Fluor-phthalsaeure-anhydrid
  • 4-Fluorophthalic anhydride - [F4888]
  • 319-03-9
  • 316-03-9
  • C8H3FO3
  • C8H3FNO3
  • Organic Building Blocks
  • Carbonyl Compounds
  • Carboxylic Acid Anhydrides
  • Building Blocks
  • Heterocycles
  • Carbonyl Compounds
  • Carboxylic Acid Anhydrides
  • Organic Building Blocks
  • Phthalic Acids, Esters and Derivatives
  • API intermediates