ChemicalBook > CAS DataBase List > 2-(2-fluorophenyl)-6,7-methylenedioxy-2-4-quinolone hydrate, NSC 656158

2-(2-fluorophenyl)-6,7-methylenedioxy-2-4-quinolone hydrate, NSC 656158

Product Name
2-(2-fluorophenyl)-6,7-methylenedioxy-2-4-quinolone hydrate, NSC 656158
CAS No.
154554-41-3
Chemical Name
2-(2-fluorophenyl)-6,7-methylenedioxy-2-4-quinolone hydrate, NSC 656158
Synonyms
CHM 1;NSC 656158;CHM-1 hydrate;CHM1, Antitumor agent;6-(2-Fluorophenyl)-1,3-dioxolo[4,5-g]quinolin-8(5H)-one;6-(2-Fluoro-phenyl)-5H-[1,3]dioxolo[4,5-g]quinolin-8-one;1,3-Dioxolo[4,5-g]quinolin-8(5H)-one, 6-(2-fluorophenyl)-;2-(2-fluorophenyl)-6,7-methylenedioxy-2-4-quinolone hydrate;2-(2-fluorophenyl)-6,7-methylenedioxy-2-4-quinolone hydrate, NSC 656158;Inhibitor,microtubule-destabilizing,Cdc2,carcinoma,CHM1,NSC-656158,Microtubule/Tubulin,hepatocellular,NSC656158,antitumor,inhibit,CHM-1,CHM 1,antimitotic,NSC 656158
CBNumber
CB52096271
Molecular Formula
C16H10FNO3
Formula Weight
283.25
MOL File
154554-41-3.mol
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2-(2-fluorophenyl)-6,7-methylenedioxy-2-4-quinolone hydrate, NSC 656158 Property

storage temp. 
2-8°C
solubility 
DMSO: ≥5mg/mL
form 
solid
color 
Off-white to light yellow
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
C381168
Product name
CHM-1
Packaging
5mg
Price
$160
Updated
2021/12/16
Usbiological
Product number
254966
Product name
CHM 1
Packaging
10mg
Price
$423
Updated
2021/12/16
ApexBio Technology
Product number
A4450
Product name
CHM1
Packaging
10mg
Price
$259
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
INB0001053
Product name
CHM-1 HYDRATE
Purity
95.00%
Packaging
5MG
Price
$770.56
Updated
2021/12/16
ApexBio Technology
Product number
A4450
Product name
CHM1
Packaging
50mg
Price
$1095
Updated
2021/12/16
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2-(2-fluorophenyl)-6,7-methylenedioxy-2-4-quinolone hydrate, NSC 656158 Chemical Properties,Usage,Production

Uses

CHM-1 is a potent apoptosis inducer.

Biological Activity

CHM-1 possess antimitotic,antiangiogenic and antitumor activity. It is a potent and selective antitumor agent in human hepatocellular carcinoma. CHM-1 induces apoptosis, and it binds tubulin and inhibits tubulin polymerization.

2-(2-fluorophenyl)-6,7-methylenedioxy-2-4-quinolone hydrate, NSC 656158 Preparation Products And Raw materials

Raw materials

Preparation Products

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2-(2-fluorophenyl)-6,7-methylenedioxy-2-4-quinolone hydrate, NSC 656158 Suppliers

3B Pharmachem (Wuhan) International Co.,Ltd.
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Bide Pharmatech Ltd.
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154554-41-3, 2-(2-fluorophenyl)-6,7-methylenedioxy-2-4-quinolone hydrate, NSC 656158Related Search:


  • 2-(2-fluorophenyl)-6,7-methylenedioxy-2-4-quinolone hydrate, NSC 656158
  • CHM-1 hydrate
  • 6-(2-Fluorophenyl)-1,3-dioxolo[4,5-g]quinolin-8(5H)-one
  • CHM 1
  • 2-(2-fluorophenyl)-6,7-methylenedioxy-2-4-quinolone hydrate
  • NSC 656158
  • 6-(2-Fluoro-phenyl)-5H-[1,3]dioxolo[4,5-g]quinolin-8-one
  • 1,3-Dioxolo[4,5-g]quinolin-8(5H)-one, 6-(2-fluorophenyl)-
  • Inhibitor,microtubule-destabilizing,Cdc2,carcinoma,CHM1,NSC-656158,Microtubule/Tubulin,hepatocellular,NSC656158,antitumor,inhibit,CHM-1,CHM 1,antimitotic,NSC 656158
  • CHM1, Antitumor agent
  • 154554-41-3