5-CHLOROPYRAZINE-2-CARBALDEHYDE
- Product Name
- 5-CHLOROPYRAZINE-2-CARBALDEHYDE
- CAS No.
- 88625-24-5
- Chemical Name
- 5-CHLOROPYRAZINE-2-CARBALDEHYDE
- Synonyms
- 5-CHLOROPYRAZINE-2-CARBALDEHYDE;5-Chloro-pyrazinecarboxaldehyde;Pyrazinecarboxaldehyde, 5-chloro-;5-Chloropyrazine-2-carboxaldehyde;5-Chloro-2-pyrazinecarboxaldehyde;2-Pyrazinecarboxaldehyde, 5-chloro-
- CBNumber
- CB52454569
- Molecular Formula
- C5H3ClN2O
- Formula Weight
- 142.54
- MOL File
- 88625-24-5.mol
5-CHLOROPYRAZINE-2-CARBALDEHYDE Property
- Boiling point:
- 221℃
- Density
- 1.432
- Flash point:
- 88℃
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- pka
- -3.78±0.10(Predicted)
- Appearance
- Off-white to light brown Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
N-Bromosuccinimide Price
- Product number
- C384323
- Product name
- 5-Chloropyrazine-2-carbaldehyde
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- 4431AC
- Product name
- 5-Chloropyrazine-2-carbaldehyde
- Packaging
- 100mg
- Price
- $120
- Updated
- 2021/12/16
- Product number
- FC162362
- Product name
- 5-Chloropyrazine-2-carboxaldehyde
- Packaging
- 100mg
- Price
- $140
- Updated
- 2021/12/16
- Product number
- 4431AC
- Product name
- 5-Chloropyrazine-2-carbaldehyde
- Packaging
- 250mg
- Price
- $151
- Updated
- 2021/12/16
- Product number
- HCH0367330
- Product name
- 5-CHLOROPYRAZINE-2-CARBALDEHYDE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $501.08
- Updated
- 2021/12/16
5-CHLOROPYRAZINE-2-CARBALDEHYDE Chemical Properties,Usage,Production
Synthesis
33332-25-1
88625-24-5
Diisobutylaluminum hydride (1.0 M toluene solution, 6.4 mL, 6.40 mmol) was added slowly and dropwise to a cooled solution of methyl 5-chloropyrazine-2-carboxylate (690 mg, 4.00 mmol) in tetrahydrofuran (THF, 13.6 mL) at -55 °C. The reaction mixture was stirred continuously at this temperature for 1 hour. Subsequently, the reaction was quenched by addition of saturated aqueous ammonium chloride solution (25 mL) and ethyl acetate (EtOAc, 25 mL). If an emulsion was formed, an aqueous 2N hydrochloric acid solution (5 mL) was added to clarify. The organic and aqueous layers were separated and the aqueous layer was then extracted with ethyl acetate. The combined organic layers were washed with saturated aqueous sodium chloride, dried over anhydrous magnesium sulfate and concentrated under reduced pressure. The resulting residue was purified by fast silica gel column chromatography with an elution gradient of 0 to 50% ethyl acetate in heptane solution. The product grades were collected and evaporated to dryness under reduced pressure to give 5-chloropyrazine-2-carbaldehyde (385 mg, 68% yield) as a beige solid.1H NMR (500 MHz, CDCl3, 27 °C) δ 8.75 (1H, d), 8.96 (1H, d), 10.15 (1H, d).
References
[1] Patent: WO2018/19793, 2018, A1. Location in patent: Page/Page column 147; 148
[2] Journal of Medicinal Chemistry, 2015, vol. 58, # 13, p. 5344 - 5354
[3] Patent: WO2012/81736, 2012, A1. Location in patent: Page/Page column 91-92
[4] Patent: WO2018/93569, 2018, A1
5-CHLOROPYRAZINE-2-CARBALDEHYDE Preparation Products And Raw materials
Raw materials
Preparation Products
5-CHLOROPYRAZINE-2-CARBALDEHYDE Suppliers
- Tel
- 025-86918202 4000255188
- Fax
- 86-025-86918232
- sales@pharmablock.com
- Country
- China
- ProdList
- 5000
- Advantage
- 55
- Tel
- 4009903999 13355009207
- Fax
- 0539-6365991
- 3007715519@qq.com
- Country
- China
- ProdList
- 18729
- Advantage
- 57
- Tel
- 021-64968085,64968086-5815,5812; 13472757003
- Fax
- +86 21 64968087
- xiaoxia.zeng@rainbowpharma.cn
- Country
- China
- ProdList
- 961
- Advantage
- 65
- Tel
- 18986259541
- Fax
- 027-87840182
- sales@3stc.com
- Country
- China
- ProdList
- 3763
- Advantage
- 58
- Tel
- 0931-4190454 13893344397
- Fax
- +86-931-8506154
- sales@kyxpharma.com
- Country
- China
- ProdList
- 310
- Advantage
- 55
- Tel
- 027-027-87342388 18086026008
- Fax
- 027-87342388
- sales@kaymke.com
- Country
- China
- ProdList
- 3731
- Advantage
- 55
- Tel
- 13971561712, 13995564702, 027-50664929
- Fax
- 027-50664927
- hbeixys2001@163.com
- Country
- China
- ProdList
- 3120
- Advantage
- 55
- Tel
- 010-57495520 13521095525
- zhw512@foxmail.com
- Country
- China
- ProdList
- 488
- Advantage
- 55
- Tel
- 400-164-7117 13681763483
- Fax
- +86-21-61629029
- product02@bidepharm.com
- Country
- China
- ProdList
- 39966
- Advantage
- 60
- Tel
- 13817873692
- Fax
- 021-31329586
- mkt@boynerspharm.com
- Country
- China
- ProdList
- 1707
- Advantage
- 55
- Tel
- 021-64340559 13651849907;
- Fax
- 021- 64345308
- xinyu_shi@jwypharmlab.com.cn
- Country
- China
- ProdList
- 12000
- Advantage
- 58
- Tel
- Fax
- -
- eric_feng1954@126.com
- Country
- China
- ProdList
- 9248
- Advantage
- 55
- Tel
- 0512-0512-52358471 17715136450
- Fax
- 05125235 6881
- sales@shiyabiopharm.com
- Country
- China
- ProdList
- 12127
- Advantage
- 58
- Tel
- 18501609135
- Fax
- -
- 182517690@qq.com
- Country
- China
- ProdList
- 219
- Advantage
- 55
- Tel
- 13675155016
- Fax
- 18912765016
- tongtf110@sina.com
- Country
- China
- ProdList
- 963
- Advantage
- 55
- Tel
- 571-89925085
- Fax
- 0086-571-89925065
- sales@amadischem.com
- Country
- China
- ProdList
- 131957
- Advantage
- 58
- Tel
- 13933818572
- Fax
- 0311-82870388
- 1519554262@qq.com
- Country
- China
- ProdList
- 1785
- Advantage
- 58
- Tel
- 025-58859352 18068836627
- Fax
- (5)02557626880
- dt3@aikonchem.com
- Country
- China
- ProdList
- 15493
- Advantage
- 58
- Tel
- 13918479294
- Fax
- -
- xiebenfa@163.com
- Country
- China
- ProdList
- 4087
- Advantage
- 58
- Tel
- 400-8210725 400821072
- Fax
- 021-58955996
- malulu@leyan.com
- Country
- China
- ProdList
- 25000
- Advantage
- 58
- Tel
- 027-51831887 15337167856
- Fax
- 027-51837635 QQ1165326703
- hubeixinyuanshun@163.com
- Country
- China
- ProdList
- 10295
- Advantage
- 58
- Tel
- 4009004166/18616739031 18616739031
- 3007523370@qq.com
- Country
- China
- ProdList
- 52687
- Advantage
- 58
- Tel
- 18916696128
- service@snowpharm.com
- Country
- China
- ProdList
- 1369
- Advantage
- 58
- Tel
- 021-58581007 18019463053
- Fax
- 021-50966098
- sales@coolpharm.com
- Country
- China
- ProdList
- 12878
- Advantage
- 58
- Tel
- 13761817188
- 774028079@qq.com
- Country
- China
- ProdList
- 291
- Advantage
- 58
- Tel
- +86-023-62871537
- sales@rosewachem.com
- Country
- China
- ProdList
- 2803
- Advantage
- 58
- Tel
- 0931-4190454 13893344397
- sales@kyxpharma.com
- Country
- China
- ProdList
- 3153
- Advantage
- 58
- Tel
- zhiqianbio@126.com
- Country
- China
- ProdList
- 19778
- Advantage
- 58
- Tel
- +86-400-0216110 +86-15958047586
- Fax
- 0086-21-33275002
- sales@allfluoro.com
- Country
- China
- ProdList
- 11385
- Advantage
- 58
- Tel
- +86-0551-65418684 +8618949823763
- Fax
- 0086-551-65418684
- sales@tnjchem.com
- Country
- China
- ProdList
- 25356
- Advantage
- 58
- Tel
- +86-27-50766799 +8618062016861
- contact@labnetwork.com
- Country
- China
- ProdList
- 19987
- Advantage
- 58
- Tel
- +86-0571-88938639 +8617705817739
- Fax
- +86-571-88938652，+86-571- 88492614
- info@dycnchem.com
- Country
- China
- ProdList
- 52846
- Advantage
- 58
- Tel
- +86-0371-86658258 +8613203830695
- Fax
- 0371-86658258
- laboratory@coreychem.com
- Country
- China
- ProdList
- 30229
- Advantage
- 58
- Tel
- 0510-86838766 13636419861
- 2258830676@qq.com
- Country
- China
- ProdList
- 5044
- Advantage
- 58
- Tel
- 17321241880
- 485229790@qq.com
- Country
- China
- ProdList
- 1750
- Advantage
- 58
- Tel
- 025-58855213
- hongjiling@feihongtec.com
- Country
- China
- ProdList
- 783
- Advantage
- 58
- Tel
- 021-20432219 13918097649
- Fax
- QQ79021576
- li_jinfei@acblock-lab.com
- Country
- China
- ProdList
- 9673
- Advantage
- 58
- Tel
- 021-50795510 4000665055
- sales@accelachem.com
- Country
- China
- ProdList
- 10467
- Advantage
- 58
- Tel
- +86-023-6139-8061 +86-86-13650506873
- sales@chemdad.com
- Country
- China
- ProdList
- 39927
- Advantage
- 58
- Tel
- 021-51698675
- sales@jiejiegroup.com
- Country
- China
- ProdList
- 8020
- Advantage
- 58
- Tel
- 022-23989838 13810451150
- 44766350@qq.com
- Country
- China
- ProdList
- 2348
- Advantage
- 58
- Tel
- +8618523575427
- sales@conier.com
- Country
- China
- ProdList
- 49975
- Advantage
- 58
- Tel
- 021-58461859 15821823057
- service@aiviche.com
- Country
- China
- ProdList
- 49312
- Advantage
- 58
- Tel
- +86-0371-86658258 +8613203830695
- Fax
- 0086-371-86658258
- factory@coreychem.com
- Country
- China
- ProdList
- 29798
- Advantage
- 58
- Tel
- +8613580539051
- joe@yuhengpharm.com
- Country
- CHINA
- ProdList
- 21142
- Advantage
- 58
- Tel
- 0531-88762217 18301471076
- sales@acespharma.com
- Country
- China
- ProdList
- 3863
- Advantage
- 58
- Tel
- 0519-68985668 13685222090
- Fax
- qq735434464
- sales@kechem.cn
- Country
- China
- ProdList
- 26028
- Advantage
- 58
- Tel
- 19106202509
- Fax
- QQ 3626423147
- 3626423147@qq.com
- Country
- China
- ProdList
- 999
- Advantage
- 58
- Tel
- 0371-0371-55135753 18003832934
- Fax
- QQ：2853979818
- 2853979818@qq.com
- Country
- China
- ProdList
- 9991
- Advantage
- 58
- Tel
- 15216675652
- xuanyuelj@163.com
- Country
- China
- ProdList
- 2864
- Advantage
- 58
View Lastest Price from 5-CHLOROPYRAZINE-2-CARBALDEHYDE manufacturers
- Product
- 5-CHLOROPYRAZINE-2-CARBALDEHYDE 88625-24-5
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 95-99%
- Supply Ability
- 1ton
- Release date
- 2020-01-02