7,27-dihydroxycholesterol

Product Name: 7,27-dihydroxycholesterol
CAS No.: 240129-43-5
Chemical Name: 7,27-dihydroxycholesterol
Synonyms: 7β;27-DHC;Cholesterol Impurity 36;7,27-dihydroxycholesterol;7ss,27-dihydroxycholesterol;7β,27-dihydroxy Cholesterol;(3β,7β,25R)-Cholest-5-ene-3,7,26-triol;Cholest-5-ene-3,7,26-triol, (3β,7β,25R)-;7β,27dihydroxy Cholesterol,7β,27 dihydroxy Cholesterol
CBNumber: CB52719903
Molecular Formula: C27H46O3
Formula Weight: 418.65
MOL File: 240129-43-5.mol

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7,27-dihydroxycholesterol Property

storage temp.: Store at -20°C
solubility: DMF: 2 mg/ml,Ethanol: 20 mg/ml,Ethanol:PBS (pH 7.2) (1:2): 0.30 mg/ml
form: A crystalline solid
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 20102
Product name: 7β,27-dihydroxy Cholesterol
Packaging: 500μg
Price: $121
Updated: 2024/03/01

Cayman Chemical

Product number: 20102
Product name: 7β,27-dihydroxy Cholesterol
Packaging: 1mg
Price: $230
Updated: 2024/03/01

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7,27-dihydroxycholesterol Chemical Properties,Usage,Production

Uses

(3β,7β,25R)-Cholest-5-ene-3,7,26-triol is a steroid derivative is used as an important signaling molecule. Oxygenated derivative of cholesterol.

Definition

ChEBI: 7beta,27-dihydroxycholesterol is a bile acid.

Biological Activity

7β,27-dihydroxycholesterol (7β27OHC) is a retinoid-related orphan receptor γ (RORγ) ligand. 7β27OHC favors smoothened (Smo) functionality.

in vivo

7?,27-Dihydroxycholesterol (60 mg/kg; s.c.; twice daily for 3 d) induces IL-17 production in mice in vivo^[1].

IC 50

RORγt: 120 nM (Ki)

7,27-dihydroxycholesterol Preparation Products And Raw materials

Raw materials

Preparation Products

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240129-43-5, 7,27-dihydroxycholesterolRelated Search:

7,27-dihydroxycholesterol

7ss,27-dihydroxycholesterol

Cholest-5-ene-3,7,26-triol, (3β,7β,25R)-

(3β,7β,25R)-Cholest-5-ene-3,7,26-triol

Cholesterol Impurity 36

27-DHC

7β

7β,27-dihydroxy Cholesterol

7β,27dihydroxy Cholesterol,7β,27 dihydroxy Cholesterol

240129-43-5