T2-aminoalcohol hydrochloride

Product Name: T2-aminoalcohol hydrochloride
CAS No.: 1380782-27-3
Chemical Name: T2-aminoalcohol hydrochloride
Synonyms: T2AA hydrochloride;T2AA, 10 mM in DMSO;T2-aminoalcohol hydrochloride;T2AA, Proliferating cell nuclear antigen (PCNA) inhibitor;(βS)-β-Amino-4-(4-hydroxyphenoxy)-3,5-diiodobenzenpropanol;(S)-4-(4-(2-Amino-2-hydroxypropyl)-2,6-diiodophenoxy)phenol;4-{4-[(2S)-2-amino-3-hydroxypropyl]-2,6-diiodophenoxy}phenol;Benzenepropanol, β-amino-4-(4-hydroxyphenoxy)-3,5-diiodo-, (βS)-;(S)-4-(4-(2-amino-3-hydroxypropyl)-2,6-diiodophenoxy)phenol hydrochloride
CBNumber: CB52751075
Molecular Formula: C15H16ClI2NO3
Formula Weight: 547.554
MOL File: 1380782-27-3.mol

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T2-aminoalcohol hydrochloride Property

storage temp.: 2-8°C
solubility: DMSO: soluble10mg/mL, clear
form: powder
color: white to beige

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML0794
Product name: T2AA hydrochloride
Purity: ≥98% (HPLC)
Packaging: 5mg
Price: $115.9
Updated: 2025/07/31

Sigma-Aldrich

Product number: SML0794
Product name: T2AA hydrochloride
Purity: ≥98% (HPLC)
Packaging: 25mg
Price: $496
Updated: 2025/07/31

Cayman Chemical

Product number: 21921
Product name: T2AA (hydrochloride)
Packaging: 5mg
Price: $89
Updated: 2023/01/06

Cayman Chemical

Product number: 21921
Product name: T2AA (hydrochloride)
Packaging: 25mg
Price: $373
Updated: 2023/01/06

Cayman Chemical

Product number: 21921
Product name: T2AA (hydrochloride)
Packaging: 1mg
Price: $28
Updated: 2023/01/06

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T2-aminoalcohol hydrochloride Chemical Properties,Usage,Production

Uses

T2AA is a small molecule inhibitor of PCNA/PIP-box interactions, which suppresses translesion DNA synthesis.

Uses

T2AA hydrochloride has been used as a chemical inhibitor of proliferating cell nuclear antigen (PCNA) in vaccinia virus.

Biochem/physiol Actions

T2AA is an inhibitor of PCNA/ PIP-Box interactions that binds to the PCNA cavity that interacts with PIP-Box sequences. Also T2AA inhibits PCNA Polδ3 interaction. T2AA inhibits de novo DNA synthesis, and in combination of cisplatin significantly increases growth inhibition in cancer cells. T2AA is a T3 analog that exhibits almost no thyroid hormone activity.

storage

Store at -20°C

T2-aminoalcohol hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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T2-aminoalcohol hydrochloride Suppliers

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1380782-27-3, T2-aminoalcohol hydrochlorideRelated Search:

(S)-4-(4-(2-amino-3-hydroxypropyl)-2,6-diiodophenoxy)phenol hydrochloride

T2AA hydrochloride

T2-aminoalcohol hydrochloride

(βS)-β-Amino-4-(4-hydroxyphenoxy)-3,5-diiodobenzenpropanol

Benzenepropanol, β-amino-4-(4-hydroxyphenoxy)-3,5-diiodo-, (βS)-

(S)-4-(4-(2-Amino-2-hydroxypropyl)-2,6-diiodophenoxy)phenol

4-{4-[(2S)-2-amino-3-hydroxypropyl]-2,6-diiodophenoxy}phenol

T2AA, Proliferating cell nuclear antigen (PCNA) inhibitor

T2AA, 10 mM in DMSO

1380782-27-3