T2-aminoalcohol hydrochloride
- Product Name
- T2-aminoalcohol hydrochloride
- CAS No.
- 1380782-27-3
- Chemical Name
- T2-aminoalcohol hydrochloride
- Synonyms
- T2AA hydrochloride;T2AA, 10 mM in DMSO;T2-aminoalcohol hydrochloride;T2AA, Proliferating cell nuclear antigen (PCNA) inhibitor;(βS)-β-Amino-4-(4-hydroxyphenoxy)-3,5-diiodobenzenpropanol;(S)-4-(4-(2-Amino-2-hydroxypropyl)-2,6-diiodophenoxy)phenol;4-{4-[(2S)-2-amino-3-hydroxypropyl]-2,6-diiodophenoxy}phenol;Benzenepropanol, β-amino-4-(4-hydroxyphenoxy)-3,5-diiodo-, (βS)-;(S)-4-(4-(2-amino-3-hydroxypropyl)-2,6-diiodophenoxy)phenol hydrochloride
- CBNumber
- CB52751075
- Molecular Formula
- C15H16ClI2NO3
- Formula Weight
- 547.554
- MOL File
- 1380782-27-3.mol
T2-aminoalcohol hydrochloride Property
- storage temp.
- 2-8°C
- solubility
- DMSO: soluble10mg/mL, clear
- form
- powder
- color
- white to beige
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- SML0794
- Product name
- T2AA hydrochloride
- Purity
- ≥98% (HPLC)
- Packaging
- 5mg
- Price
- $115.9
- Updated
- 2025/07/31
- Product number
- SML0794
- Product name
- T2AA hydrochloride
- Purity
- ≥98% (HPLC)
- Packaging
- 25mg
- Price
- $496
- Updated
- 2025/07/31
- Product number
- 21921
- Product name
- T2AA (hydrochloride)
- Packaging
- 5mg
- Price
- $89
- Updated
- 2023/01/06
- Product number
- 21921
- Product name
- T2AA (hydrochloride)
- Packaging
- 25mg
- Price
- $373
- Updated
- 2023/01/06
- Product number
- 21921
- Product name
- T2AA (hydrochloride)
- Packaging
- 1mg
- Price
- $28
- Updated
- 2023/01/06
T2-aminoalcohol hydrochloride Chemical Properties,Usage,Production
Uses
T2AA is a small molecule inhibitor of PCNA/PIP-box interactions, which suppresses translesion DNA synthesis.
Uses
T2AA hydrochloride has been used as a chemical inhibitor of proliferating cell nuclear antigen (PCNA) in vaccinia virus.
Biochem/physiol Actions
T2AA is an inhibitor of PCNA/ PIP-Box interactions that binds to the PCNA cavity that interacts with PIP-Box sequences. Also T2AA inhibits PCNA Polδ3 interaction. T2AA inhibits de novo DNA synthesis, and in combination of cisplatin significantly increases growth inhibition in cancer cells. T2AA is a T3 analog that exhibits almost no thyroid hormone activity.
storage
Store at -20°C
T2-aminoalcohol hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
T2-aminoalcohol hydrochloride Suppliers
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