3-HYDROXY-4-PYRIDINECARBOXYLIC ACID
- Product Name
- 3-HYDROXY-4-PYRIDINECARBOXYLIC ACID
- CAS No.
- 10128-71-9
- Chemical Name
- 3-HYDROXY-4-PYRIDINECARBOXYLIC ACID
- Synonyms
- 3-Hydroxyisonicotinicaci;3-HYDROXYISONICOTINIC ACID;3-Hydroxy-4-carboxypyridine;3-HydroxyisonicotinicAcid>3-hydroxypyridin-4-carboxylic acid;3-Hydroxy-4-pyridinecaboxylic acid;3-HYDROXY-4-PYRIDINECARBOXYLIC ACID;3-HYDROXY PYRIDINE-4-CARBOXYLIC ACID;4-Pyridinecarboxylic acid, 3-hydroxy-;3-Hydroxy-4-pyridinecarboxylic acid ,97%
- CBNumber
- CB5280168
- Molecular Formula
- C6H5NO3
- Formula Weight
- 139.11
- MOL File
- 10128-71-9.mol
3-HYDROXY-4-PYRIDINECARBOXYLIC ACID Property
- Melting point:
- 317-319(dec.)
- Boiling point:
- 519.3±35.0 °C(Predicted)
- Density
- 1.485±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- pka
- 0.51±0.10(Predicted)
- form
- Solid
- color
- Light yellow to Brown
- Water Solubility
- Soluble in methanol. Slightly soluble in water.
- CAS DataBase Reference
- 10128-71-9(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36/37/39
- HazardClass
- IRRITANT
- HS Code
- 29333990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- H1377
- Product name
- 3-Hydroxyisonicotinic Acid
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 1g
- Price
- $59
- Updated
- 2025/07/31
- Product number
- H1377
- Product name
- 3-Hydroxyisonicotinic Acid
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 5g
- Price
- $236
- Updated
- 2025/07/31
- Product number
- H943565
- Product name
- 3-Hydroxyisonicotinic Acid
- Packaging
- 1g
- Price
- $130
- Updated
- 2021/12/16
- Product number
- P000022671
- Product name
- 3-Hydroxyisonicotinic acid
- Purity
- 97%
- Packaging
- 1g
- Price
- $9
- Updated
- 2021/12/16
- Product number
- 044485
- Product name
- 3-Hydroxyisonicotinic acid
- Purity
- 95+%
- Packaging
- 1g
- Price
- $11
- Updated
- 2021/12/16
3-HYDROXY-4-PYRIDINECARBOXYLIC ACID Chemical Properties,Usage,Production
Chemical Properties
Light yellow solid
Uses
3-Hydroxyisonicotinic Acid is used in the preparation of chelating agents for iron and aluminum.
Synthesis
7579-20-6
10128-71-9
Step B: Synthesis of 3-hydroxyisonicotinic acid: 3-aminoisonicotinic acid (108.86 g, 788.13 mmol) was dissolved in water (1740 mL), followed by slow addition of sulfuric acid (84.020 mL, 1576.3 mmol). The resulting yellow slurry was cooled to below 10°C and a solution of sodium nitrite (60.359 g, 874.83 mmol) in water (510 mL) was added dropwise while maintaining the temperature below 10°C. Subsequently, the reaction mixture was heated to 80°C, at which point a large amount of precipitate generation was observed. After the suspension was cooled to 65°C, glacial acetic acid (88 mL, continuous decantation) and concentrated ammonium hydroxide (190 mL) were added sequentially to adjust the final pH to about 4.5. The precipitate was collected by vacuum filtration and washed with cold water. The solid was dried in air for 16 h to give the final free flowing granular 3-hydroxyisonicotinic acid (99.37 g, 91% yield).
References
[1] Patent: US2007/49603, 2007, A1. Location in patent: Page/Page column 78; 30
[2] Patent: WO2008/24725, 2008, A1. Location in patent: Page/Page column 67
[3] Journal of Medicinal Chemistry, 2017, vol. 60, # 16, p. 6942 - 6990
3-HYDROXY-4-PYRIDINECARBOXYLIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 3-HYDROXY-4-PYRIDINECARBOXYLIC ACID manufacturers
- Product
- 3-HYDROXY-4-PYRIDINECARBOXYLIC ACID 10128-71-9
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-10-14
- Product
- 3-HYDROXY-4-PYRIDINECARBOXYLIC ACID 10128-71-9
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-10-25
- Product
- 3-HYDROXY-4-PYRIDINECARBOXYLIC ACID 10128-71-9
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-11