ChemicalBook > CAS DataBase List > ML334
ML334
- Product Name
- ML334
- CAS No.
- 1432500-66-7
- Chemical Name
- ML334
- Synonyms
- ML334;LH601A;ML334,ML-334;ML334, 10 mM in DMSO;Keap1-Nrf2 Interaction Probe, ML334;(1S,2R)-2-[[(1S)-1-[(1,3-Dihydro-1,3-dioxo-2H-isoindol-2-yl)methyl]-3,4-dihydro-2(1H)-isoquinolinyl]carbonyl]cyclohexanecarboxylic acid;(1S,2R)-2-[(1S)-1-[(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)methyl]-1,2,3,4-tetrahydroisoquinolin-2-carbonyl]cyclohexane-1-carboxylic acid;Cyclohexanecarboxylic acid, 2-[[(1S)-1-[(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)methyl]-3,4-dihydro-2(1H)-isoquinolinyl]carbonyl]-, (1S,2R)-
- CBNumber
- CB53159380
- Molecular Formula
- C26H26N2O5
- Formula Weight
- 446.49
- MOL File
- 1432500-66-7.mol
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ML334 Property
- Boiling point:
- 693.1±55.0 °C(Predicted)
- Density
- 1.354±0.06 g/cm3(Predicted)
- storage temp.
- Store at 4°C, stored under nitrogen
- solubility
- DMSO: 40 mg/ml
- form
- A solid
- pka
- 4.69±0.44(Predicted)
- color
- White to off-white
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N-Bromosuccinimide Price
Tocris
- Product number
- 5625
- Product name
- ML334
- Purity
- ≥98%(HPLC)
- Packaging
- 5
- Price
- $135
- Updated
- 2021/12/16
TRC
- Product number
- M425438
- Product name
- ML334
- Packaging
- 5mg
- Price
- $1800
- Updated
- 2021/12/16
AK Scientific
- Product number
- 1549DN
- Product name
- (1S,2R)-2-[(1S)-1-[(1,3-Dioxoisoindol-2-yl)methyl]-3,4-dihydro-1H-isoquinoline-2-carbonyl]cyclohexane-1-carboxylicacid
- Packaging
- 1mg
- Price
- $139
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0033123
- Product name
- ML334
- Purity
- 99.82%
- Packaging
- 1mg
- Price
- $185
- Updated
- 2021/12/16
AK Scientific
- Product number
- 1549DN
- Product name
- (1S,2R)-2-[(1S)-1-[(1,3-Dioxoisoindol-2-yl)methyl]-3,4-dihydro-1H-isoquinoline-2-carbonyl]cyclohexane-1-carboxylicacid
- Packaging
- 5mg
- Price
- $276
- Updated
- 2021/12/16
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ML334 Chemical Properties,Usage,Production
Uses
ML 334 is an inhibitor of Keap1-Nrf2 interaction and affects the cytoprotective responses to oxidative and electrophilic stress. May be used in cancer treatment and attenuation.
Definition
ChEBI: (1S,2R)-2-[[(1S)-1-[(1,3-dioxo-2-isoindolyl)methyl]-3,4-dihydro-1H-isoquinolin-2-yl]-oxomethyl]-1-cyclohexanecarboxylic acid is a member of phthalimides.
Biological Activity
Primary Target
Keap1–Nrf2', 'Reversible: yes
storage
Store at -20°C
ML334 Preparation Products And Raw materials
Raw materials
Preparation Products
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ML334 Suppliers
- Tel
- --
- Fax
- --
- customerservice@tocris.co.uk
- Country
- United Kingdom
- ProdList
- 5726
- Advantage
- 77