Duvoglustat Hydrochloride
- Product Name
- Duvoglustat Hydrochloride
- CAS No.
- 308362-25-6
- Chemical Name
- Duvoglustat Hydrochloride
- Synonyms
- SMT19969;Ridinilazole, 10 mM in DMSO;5,5'-Bi-1H-benzimidazole, 2,2'-di-4-pyridinyl-;2,2'-Di(pyridin-4-yl)-1H,1'H-5,5'-bibenzo[d]imidazole;2,2'-di(pyridin-4-yl)-3H,3'H-5,5'-bibenzo[d]imidazole;SMT 19969,inhibit,SMT-19969,Bacterial,Ridinilazole,Inhibitor
- CBNumber
- CB53159890
- Molecular Formula
- C24H16N6
- Formula Weight
- 388.42
- MOL File
- 308362-25-6.mol
Duvoglustat Hydrochloride Property
- Boiling point:
- 774.9±70.0 °C(Predicted)
- Density
- 1.372±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO : ≥ 60 mg/mL (154.47 mM)
- pka
- 9.84±0.10(Predicted)
- form
- Solid
- color
- Light yellow to yellow
- InChI
- InChI=1S/C24H16N6/c1-3-19-21(29-23(27-19)15-5-9-25-10-6-15)13-17(1)18-2-4-20-22(14-18)30-24(28-20)16-7-11-26-12-8-16/h1-14H,(H,27,29)(H,28,30)
- InChIKey
- UHQFBTAJFNVZIV-UHFFFAOYSA-N
- SMILES
- C1(C2C=CN=CC=2)NC2=CC=C(C3=CC=C4NC(C5C=CN=CC=5)=NC4=C3)C=C2N=1
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- CS-6591
- Product name
- Ridinilazole
- Purity
- 99.51%
- Packaging
- 1mg
- Price
- $120
- Updated
- 2021/12/16
- Product number
- CS-6591
- Product name
- Ridinilazole
- Purity
- 99.51%
- Packaging
- 5mg
- Price
- $240
- Updated
- 2021/12/16
- Product number
- CS-6591
- Product name
- Ridinilazole
- Purity
- 99.51%
- Packaging
- 10mg
- Price
- $408
- Updated
- 2021/12/16
- Product number
- CS-6591
- Product name
- Ridinilazole
- Purity
- 99.51%
- Packaging
- 20mg
- Price
- $720
- Updated
- 2021/12/16
Duvoglustat Hydrochloride Chemical Properties,Usage,Production
Uses
Ridinilazole is a novel antibacterial with MICs range of 0.06-0.25?μg/mL (MIC90=8?μg/mL) against C.?difficile.
in vivo
In a hamster model of CDI with a once-daily dosing regimen, Ridinilazole displays greater efficacy than Vancomycin both against non-epidemic and epidemic strains of C.?difficile. Similar to the twice-daily dosing study, plasma levels of Ridinilazole are below the level of detection, whereas caecal Ridinilazole concentrations are well above the MIC, thus demonstrating the non-absorbable nature of Ridinilazole and minimal systemic exposure[1].
References
[1] Vickers RJ, et al. Ridinilazole: a novel therapy for Clostridium difficile infection. Int J Antimicrob Agents. 2016 Aug;48(2):137-43. DOI:10.1016/j.ijantimicag.2016.04.026
Duvoglustat Hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
Duvoglustat Hydrochloride Suppliers
- Tel
- 021-58955995
- Fax
- 609-228-5909
- sales@medchemexpress.cn
- Country
- United States
- ProdList
- 4861
- Advantage
- 58
- Tel
- +1-781-999-5354; +17819995354
- marketing@targetmol.com
- Country
- United States
- ProdList
- 32435
- Advantage
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