ChemicalBook > CAS DataBase List > Fmoc-NH-PEG12-CH2CH2COOH

Fmoc-NH-PEG12-CH2CH2COOH

Product Name
Fmoc-NH-PEG12-CH2CH2COOH
CAS No.
1952360-91-6
Chemical Name
Fmoc-NH-PEG12-CH2CH2COOH
Synonyms
5,8,11,14,17,20,23,26,29,32,35,38-Dodecaoxa-2-azahentetracontanedioic acid, 1-(9H-fluoren-9-ylmethyl) ester;Fmoc-nh-peg(16)-cooh;Fmoc-nh-peg12-C2-cooh;FMoc-NH-PEG12-CH2CH2COOH;Carboxy-PEG12-(Fmoc-amine);Fmoc-N-amido-PEG12-propionic acid;(Fmoc-amino)-PEG12-C2-Carboxylic Acid;Inhibitor,Fmoc-NH-PEG-12-CH2CH2COOH,inhibit,Fmoc NH PEG12 CH2CH2COOH,PROTAC Linkers,FmocNHPEG12CH2CH2COOH;1-(9H-Fluoren-9-yl)-3-oxo-2,7,10,13,16,19,22,25,28,31,34,37,40-tridecaoxa-4-azatritetracontan-43-oic Acid;FmocNH-PEG12-CH2CH2COOH/5,8,11,14,17,20,23,26,29,32,35,38-Dodecaoxa-2-azahentetracontanedioic acid, 1-(9H-fluoren-9-ylmethyl) ester
CBNumber
CB53371186
Molecular Formula
C42H65NO16
Formula Weight
839.96
MOL File
1952360-91-6.mol
More
Less

Fmoc-NH-PEG12-CH2CH2COOH Property

Boiling point:
870.4±65.0 °C(Predicted)
Density 
1.175±0.06 g/cm3(Predicted)
storage temp. 
Storage temp. 2-8°C
pka
4.28±0.10(Predicted)
form 
clear liquid
color 
Colorless to Light yellow
InChIKey
JYNHRDJTWNEGJE-UHFFFAOYSA-N
SMILES
C(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(O)=O
More
Less

Safety

HS Code 
2924297099
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

More
Less

N-Bromosuccinimide Price

TCI Chemical
Product number
F1238
Product name
(Fmoc-amino)-PEG12-C2-Carboxylic Acid
Packaging
100MG
Price
$356
Updated
2025/07/31
Apolloscientific
Product number
BIPG1405
Product name
Fmoc-N-amido-PEG12-Acid
Packaging
50mg
Price
$254
Updated
2021/12/16
Iris Biotech GmbH
Product number
PEG1080
Product name
Fmoc-NH-PEG(12)-COOH
Packaging
100mg
Price
$351
Updated
2021/12/16
Apolloscientific
Product number
BIPG1405
Product name
Fmoc-N-amido-PEG12-Acid
Packaging
100mg
Price
$399
Updated
2021/12/16
BroadPharm
Product number
BP-21632
Product name
Fmoc-N-amido-PEG12-acid
Purity
98%
Packaging
500mg
Price
$400
Updated
2021/12/16
More
Less

Fmoc-NH-PEG12-CH2CH2COOH Chemical Properties,Usage,Production

Description

Fmoc-N-amido-PEG12-acid is a PEG linker containing an Fmoc-protected amine and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Uses

Fmoc-NH-PEG12-CH2CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

General Description

FmocNH-PEG12-CH2CH2COOH is a PEG-based PROTAC linker. Fmoc-NH-PEG12-CH2CH2COOH can be used in the synthesis of PROTAC.

IC 50

PEGs

storage

Keep in dark place,Inert atmosphere,Store in freezer, under -20 ℃.

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Fmoc-NH-PEG12-CH2CH2COOH Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

Fmoc-NH-PEG12-CH2CH2COOH Suppliers

Americas 1 China 67 Europe 1 India 1 Japan 2 United States 4 Global 76
Chengdu Pukang Biotechnology Co., Ltd
Tel
+86-028-82550498 +86-19102685862
Fax
086-28-82550468
Email
sales@pu-kang.com
Country
China
ProdList
497
Advantage
58
Alabiochem Tech.Co., Ltd.
Tel
512-58900862 400-0707518
Fax
0086-512-56765862
Email
sales@alabiochem.com
Country
China
ProdList
970
Advantage
59
Guangzhou Hongyuan Chemical Co.,Ltd
Tel
15817493340
Email
981810490@qq.com
Country
China
ProdList
1566
Advantage
58
Changsha Morning Shine Co., Ltd.
Tel
189-75832125 13397510867
Email
BD@csmspharm.com
Country
China
ProdList
399
Advantage
58
Affinity（Wuhan）Ltd.
Tel
15841022315
Email
sales@affinitytech.cn
Country
China
ProdList
3000
Advantage
58
PharmaBlock Sciences (Nanjing),Inc.
Tel
025-86918202 4000255188
Fax
86-025-86918232
Email
sales@pharmablock.com
Country
China
ProdList
5000
Advantage
55
Biomatrik (Jiaxing) Inc.
Tel
573-573-82623377 18967387295
Fax
+86 (573) 8262-3317
Email
sales@biomatrik.cn
Country
China
ProdList
70
Advantage
61
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11035
Advantage
64
ChemShuttle, Inc.
Tel
0510-83588313-811 18800520310
Email
sales@chemshuttle.com
Country
China
ProdList
2999
Advantage
62
Hunan Hui Bai Shi Biotechnology Co., Ltd.
Tel
0731-85526065 13308475853
Email
ivy@hnhbsj.com
Country
China
ProdList
7247
Advantage
62
Shanghai Topbiochem Technology Co., Ltd
Tel
021-58170097
Email
info@topbiochem.com
Country
China
ProdList
9510
Advantage
58
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
39966
Advantage
60
Hunan HuaTeng Pharmaceutical Co., Ltd.,
Tel
400-8592883
Fax
0731-82251112
Email
sales@huatengsci.com
Country
China
ProdList
5872
Advantage
58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66028182 18626450290
Email
yftan@aikonchem.com
Country
China
ProdList
16679
Advantage
50
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Amatek Scientific Co. Ltd.
Tel
0512-56316828
Fax
0512-56316826
Email
info@amateksci.com
Country
China
ProdList
28785
Advantage
58
9ding chemical ( Shanghai) Limited
Tel
021-021-52271985 17721149837
Fax
+86 (21) 52271987
Email
sales@9dingchem.com
Country
China
ProdList
19800
Advantage
60
Jiaxing Deyi Chemical Co., Ltd.
Tel
86-0573-85866609 13325730825
Fax
0573-85866609
Email
945717149@qq.com
Country
China
ProdList
8593
Advantage
58
Xi'an Confluore Biological Technology Co., Ltd.
Tel
+86-156-80926068 +86-15680926068
Email
1924344760@qq.com
Country
China
ProdList
4952
Advantage
58
Shanghai Haohong Pharmaceutical Co., Ltd.
Tel
400-8210725 400821072
Fax
021-58955996
Email
malulu@leyan.com
Country
China
ProdList
25000
Advantage
58
Chengdu Zen Sunda Bio-pharmaceutical Technology Co., Ltd.
Tel
19981275275
Email
sales@zsdpharm.com
Country
China
ProdList
381
Advantage
58
Blocksynth Pharmaceutical Technology Co.,Ltd
Tel
0086-19817745290; +8619817745290
Email
bd@blocksynth.com
Country
China
ProdList
5661
Advantage
58
Labnetwork lnc.
Tel
+86-27-50766799 +8618062016861
Email
contact@labnetwork.com
Country
China
ProdList
19987
Advantage
58
Binhai gill polypeptide co. LTD
Tel
021-61263389 13524856427
Fax
WeChat630417570
Email
Joetang@glschina.com
Country
China
ProdList
10000
Advantage
58
Guangdong Wengjiang Chemical Reagent Co., Ltd.
Tel
0751-2886766 13927870850
Fax
0751-2886756
Email
3001267247@qq.com
Country
China
ProdList
9941
Advantage
58
Energy Chemical
Tel
021-58432009 400-005-6266
Fax
021-58436166
Email
marketing1@energy-chemical.com
Country
China
ProdList
44894
Advantage
58
Shanghai Sunway Pharmaceutical Technology Co.,Ltd.
Tel
021-51816796-820 13611835272
Fax
021-5161 3951
Email
sales2@sunwaypharm.com
Country
China
ProdList
44119
Advantage
58
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 15801484223;
Email
psaitong@jm-bio.com
Country
China
ProdList
29757
Advantage
58
Nanjing Yili Biotechnology Co., Ltd.
Tel
15380789538
Email
2885743537@qq.com
Country
China
ProdList
8205
Advantage
58
JinOu Biomedical (Nanjing) Co., Ltd.
Tel
13000000000
Fax
jinoupharma@163
Email
jinoupharma@163.com
Country
China
ProdList
11721
Advantage
58
Wuhan Augda Biotechnology Co., Ltd
Tel
15071299552
Fax
QQ:262933239
Email
262933239@qq.com
Country
China
ProdList
7048
Advantage
58
Shanghai Huici Pharmaceutical Technology Co., LTD
Tel
133-31922809 19372841038
Email
lixing@pharmahuici.com
Country
China
ProdList
732
Advantage
58
Zhejiang Rui 'ao Biological Technology Co.,LTD.
Tel
+86-573-82087565 15757883359
Email
yan@ruiaochem.cn
Country
China
ProdList
640
Advantage
58
Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd
Tel
0431-80514535 19917294565
Email
et@chemextension.com
Country
China
ProdList
5061
Advantage
58
Wuhan Yingnuo Pharmaceutical Technology Co., Ltd.
Tel
15387063101
Email
2881924050@qq.com
Country
China
ProdList
9960
Advantage
58
TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
ProdList
24961
Advantage
58
Guangdong Fangxin Biotechnology Co., Ltd.
Tel
0751-2838688 13376594225
Email
1276075424@qq.com
Country
China
ProdList
9942
Advantage
58
G-CLONE
Tel
400-910-1997 15330005590
Email
3546414794@qq.com
Country
China
ProdList
9959
Advantage
58
Shanghai Easy CDMO Co.,Ltd
Tel
021-61734564 13854185395;
Email
info@easycdmo.com
Country
China
ProdList
10024
Advantage
58
Beijing Solarbio Science & Tecnology Co., Ltd.
Tel
010-50973130 17801761073
Email
Gsiyu@solarbio.com
Country
China
ProdList
50464
Advantage
58
Shanghai Jieshikai Biotechnology Co. , Ltd.
Tel
021-57520305 13795461237
Email
zhuruyan@jskchem.com
Country
China
ProdList
49234
Advantage
58
Lianhe Aigen Pharmatech Co.,Ltd.
Tel
18918657159
Email
sales-Aigen@lianhetech.com
Country
China
ProdList
3000
Advantage
58
Shandong Mingde Biotechnology Co., Ltd.
Tel
18560864701
Email
643971@qq.com
Country
China
ProdList
6098
Advantage
58
Shandong fen Boyu Biotechnology Co.,LTD
Tel
13356310019 13356310019;
Email
boyu2024@163.com
Country
China
ProdList
3247
Advantage
58
Chengdu Hanwei Biotechnology Co., Ltd
Tel
17360178904 18217049878
Email
zengzongwen@pegtide.com
Country
China
ProdList
1222
Advantage
58
Ningbo Zhenyue Pharmaceutical Technology Co., Ltd
Tel
19817745290
Email
bd@blocksynth.com
Country
China
ProdList
5869
Advantage
58
Jilin Shengchuang Biotechnology Co., LTD
Tel
13251734045; 13251734045
Email
396921152@qq.com
Country
China
ProdList
507
Advantage
58
Shanghai Zunlijia Life Technology Co., Ltd
Tel
021-34045219 13062664914
Email
huji@zunlijia.com
Country
China
ProdList
10027
Advantage
58
Jilin Chinese Academy of Sciences-yanshen Technology
Tel
18143011203
Email
ET-market@chemextension.com
Country
China
ProdList
32034
Advantage
58
Hubei wei shi reagent group ltd., company
Tel
027-59102966 18717199209
Email
2853877583@QQ.com
Country
China
ProdList
7498
Advantage
58
More
Less

View Lastest Price from Fmoc-NH-PEG12-CH2CH2COOH manufacturers

LAURENT
Product
Fmoc-NH-PEG12-CH2CH2COOH 1952360-91-6
Price
US $283.00/g
Min. Order
1g
Purity
98%
Supply Ability
300kg
Release date
2025-11-17
Xian confluore Biological Technology Co., Ltd.
Product
Fmoc-N-amido-PEG12-acid 1952360-91-6
Price
US $0.00/g
Min. Order
5g
Purity
>99.00%
Supply Ability
5g
Release date
2024-03-25

1952360-91-6, Fmoc-NH-PEG12-CH2CH2COOHRelated Search:

Fmoc-N-amido-PEG36-acid FMoc-NH-PEG9-CH2CH2COOH FMoc-NH-PEG7-CH2CH2COOH Fmoc-NH-PEG8-CH2CH2COOH Carbamic acid, N-[2-[2-(aminooxy)ethoxy]ethoxy]-, 9H-fluoren-9-ylmethyl ester Fmoc-N-amido-PEG24-acid FMOC-21-AMINO-4,7,10,13,16,19-HEXAOXAHENEICOSANOIC ACID Fmoc-n-amido-peg10-acid Fmoc-NH-PEG11-CH2CH2COOH

  • Fmoc-nh-peg(16)-cooh
  • (Fmoc-amino)-PEG12-C2-Carboxylic Acid
  • 5,8,11,14,17,20,23,26,29,32,35,38-Dodecaoxa-2-azahentetracontanedioic acid, 1-(9H-fluoren-9-ylmethyl) ester
  • Fmoc-nh-peg12-C2-cooh
  • 1-(9H-Fluoren-9-yl)-3-oxo-2,7,10,13,16,19,22,25,28,31,34,37,40-tridecaoxa-4-azatritetracontan-43-oic Acid
  • Carboxy-PEG12-(Fmoc-amine)
  • Inhibitor,Fmoc-NH-PEG-12-CH2CH2COOH,inhibit,Fmoc NH PEG12 CH2CH2COOH,PROTAC Linkers,FmocNHPEG12CH2CH2COOH
  • FmocNH-PEG12-CH2CH2COOH/5,8,11,14,17,20,23,26,29,32,35,38-Dodecaoxa-2-azahentetracontanedioic acid, 1-(9H-fluoren-9-ylmethyl) ester
  • Fmoc-N-amido-PEG12-propionic acid
  • FMoc-NH-PEG12-CH2CH2COOH
  • 3-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid
  • 1952360-91-6
  • Fmoc