ChemicalBook > CAS DataBase List > PUROMYCIN AMINONUCLEOSIDE

PUROMYCIN AMINONUCLEOSIDE

Product Name: PUROMYCIN AMINONUCLEOSIDE
CAS No.: 58-60-6
Chemical Name: PUROMYCIN AMINONUCLEOSIDE
Synonyms: ARDMA;Nsc3056;Aids000507;Aids-000507;aminonucleoside;3′-Amino-3′-deoxy-N6;3’-Amino-3’-deoxy-N6;aminonucleosidepuromycin;PuroMycin aMinonucleosid;PUROMYCIN AMINONUCLEOSIDE
CBNumber: CB5455647
Molecular Formula: C12H18N6O3
Formula Weight: 294.31
MOL File: 58-60-6.mol

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PUROMYCIN AMINONUCLEOSIDE Property

Melting point:: 235℃ (Decomposition)
Boiling point:: 436.08°C (rough estimate)
Density: 1.2131 (rough estimate)
refractive index: 1.7000 (estimate)
Flash point:: >110°(230°F)
storage temp.: Keep in dark place,Inert atmosphere,2-8°C
solubility: H₂O: 50 mg/mL, clear, slightly yellow
form: liquid
pka: 13.26±0.70(Predicted)
color: White
Water Solubility: Soluble in water at 50mg/ml. May require heating
BRN: 93902
Stability:: Stable for 1 year as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 2 months.
InChIKey: RYSMHWILUNYBFW-GRIPGOBMSA-N
EPA Substance Registry System: Adenosine, 3'-amino-3'-deoxy-N,N-dimethyl- (58-60-6)

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Safety

Hazard Codes: Xi,Xn
Risk Statements: 48/22
WGK Germany: 3
RTECS: AU7337000
F: 10-21
TSCA: Yes
HS Code: 29419090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H373May cause damage to organs through prolonged or repeated exposure

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P314Get medical advice/attention if you feel unwell.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: P7130
Product name: Puromycin aminonucleoside
Packaging: 100mg
Price: $680
Updated: 2025/07/31

Sigma-Aldrich

Product number: P7130
Product name: Puromycin aminonucleoside
Packaging: 1g
Price: $4030
Updated: 2025/07/31

Cayman Chemical

Product number: 15509
Product name: Puromycin Aminonucleoside
Purity: ≥98%
Packaging: 10mg
Price: $62
Updated: 2024/03/01

Cayman Chemical

Product number: 15509
Product name: Puromycin Aminonucleoside
Purity: ≥98%
Packaging: 25mg
Price: $142
Updated: 2024/03/01

Sigma-Aldrich

Product number: SBR00017
Product name: Puromycin aminonucleoside Ready Made Solution
Purity: 10mg/mL in water
Packaging: 1ml
Price: $162.89
Updated: 2025/07/31

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PUROMYCIN AMINONUCLEOSIDE Chemical Properties,Usage,Production

Description

Puromycin aminonucleoside (58-60-6) is the nucleoside moiety of puromycin (Cat.# 10-2100) which does not inhibit protein synthesis or induce apoptosis.1?It acts as a glomerular epithelial cell toxin2 and as such is a useful tool for producing animal models of nephropathy3,4, or puromycin aminonucleoside nephrosis (1-2.5 mg/100g rat body weight)5. Active in vivo.

Chemical Properties

White crystal

Uses

Puromycin aminonucleoside is a semi-synthetic derivative of puromycin which lacks the methoxyphenylalanyl moiety. Puromycin aminonucleoside is the key intermediate in the synthesis of semi-synthetic analogues of puromycin. It does not inhibit protein synthesis or induce apoptosis, but exhibits antitumour properties. Puromycin aminonucleoside-induced nephrosis is a well-described model of human idiopathic nephrotic syndrome, suppressing integrin expression in cultured glomerular epithelial cells.

Uses

Puromycin Aminonucleoside is an aminonucleoside portion of the antibiotic puromycin.

Definition

ChEBI: Puromycin derivative that lacks the methoxyphenylalanyl group on the amine of the sugar ring.

Safety Profile

An experimental teratogen. Other experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits toxic fumes of NOx,.

References

[1] SEK C. CHOW Sten O Iris Peters. Reevaluation of the Role of de Novo Protein Synthesis in Rat Thymocyte Apoptosis[J]. Experimental cell research, 1995, 216 1: Pages 149-159. DOI:10.1006/excr.1995.1019
[2] Puromycin aminonucleoside suppresses integrin expression in cultured glomerular epithelial cells
[3] YUKARI EGASHIRA Hiroo S Shin Nagaki. Tryptophan-niacin metabolism in rat with puromycin aminonucleoside-induced nephrosis.[J]. International Journal for Vitamin and Nutrition Research, 2006, 76 1: 28-33. DOI:10.1024/0300-9831.76.1.28
[4] M. HAGIWARA . Mitochondrial dysfunction in focal segmental glomerulosclerosis of puromycin aminonucleoside nephrosis[J]. Kidney international, 2006, 69 7: Pages 1146-1152. DOI:10.1038/sj.ki.5000207
[5] E K LÖWENBORG U B B G Jaremko. Glomerular function and morphology in puromycin aminonucleoside nephropathy in rats.[J]. Nephrology Dialysis Transplantation, 2000, 15 10: 1547-1555. DOI:10.1093/ndt/15.10.1547

PUROMYCIN AMINONUCLEOSIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from PUROMYCIN AMINONUCLEOSIDE manufacturers

Shaanxi Dideu New Materials Co. Ltd

Product: PUROMYCIN AMINONUCLEOSIDE 58-60-6
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10000KGS
Release date: 2025-02-22

Career Henan Chemical Co

Product: PUROMYCINAMINONUCLEOSIDE 58-60-6
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: KG/T
Release date: 2019-12-17

58-60-6, PUROMYCIN AMINONUCLEOSIDERelated Search:

Octyl 4-methoxycinnamate 2-Methyl-4-isothiazolin-3-one Butylparaben Imidazolidinyl urea 4'-Hydroxyacetophenone Triethanolamine Isopropyl palmitate Decanoyl/octanoyl-glycerides Cetearyl alcohol Xanthan gum PUROMYCIN DIHYDROCHLORIDE PUROMYCIN PUROMYCIN DIHYDROCHLORIDE N6,N6-DIMETHYLADENOSINE PUROMYCIN AMINONUCLEOSIDE A 201A PUROMYCIN DIHYDROCHLORIDE DIHYDRATE PUROMYCIN DIHYDROCHLORIDE, [8-3H(N)]-

3’-amino-3’-deoxy-n,n-dimethyl-adenosin

6-(dimethylamino)-9-(3-amino-3-deoxy-beta-d-ribofuranosyl)purine

9-(3-amino-3-deoxy-beta-d-ribofuranosyl)-6-(dimethylamino)-9h-purine

aminonucleoside

aminonucleosidepuromycin

stylomycinaminonucleoside

PUROMYCIN AMINONUCLEOSIDE

6-DIMETHYLAMIN-9-[3'-AMINO-3'DEOXYRIBOSYL]-PURINE

Puromycin Aminonucleoside, 6-Dimethylamin-9-[3-amino-3deoxyribosyl]-purine

9-(3-Amino-3-deoxy-.beta.-D-ribofuranosyl)-N,N-dimethyl-9H-purin-6-amine

Adenosine, 3'-amino-3'-deoxy-N,N-dimethyl-

Aids000507

Aids-000507

Nsc3056

PuroMycin aMinonucleosid

3'-DiMethylaMino-3'-deoxyadenosine

3'-AMINO-3'-DEOXY-N6,N6-DIMETHYLADENOSINE

3'-AMINO-3'-DEOXY-N,N-DIMETHYL-ADENOSINE

SAN Puromycin-Amino-Nucleoside NSC 3056 Aminonucleoside puromycin PANS

(2R,3R,4S,5S)-4-amino-2-(6-(dimethylamino)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3-ol

Puromycin aminonucleoside Ready Made Solution

puromycin aminonucleoside (PAN)

3′-Amino-3′-deoxy-N6

3’-Amino-3’-deoxy-N6,N6-dimethyladenosine, puromycin aminonucleoside (PAN)

PUROMYCIN AMINONUCLEOSIDE USP/EP/BP

(2R,3R,4S,5S)-4-amino-2-[6-(dimethylamino)purin-9-yl]-5-(hydroxymethyl)oxolan-3-ol

Puromycin Aminonucleoside (NSC-3056)

C12H18N6O3 PUROMYCIN AMINONUCLEOSIDE

58-60-6 PUROMYCIN AMINONUCLEOSIDE

ARDMA

3’-Amino-3’-deoxy-N6,N6-dimethyl?adenosine

3’-amino-3’-deoxy-n,n-dimethyl-adenosine

3’-Amino-3’-deoxy-N6

Puromycin aminonucleoside, 10 mM in DMSO

Puromycin aminonucleoside/58-60-6

58-60-6

58-60-4

C12H18N6O3

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