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GAK inhibitor 49

Product Name
GAK inhibitor 49
CAS No.
319492-82-5
Chemical Name
GAK inhibitor 49
Synonyms
AK inhibitor 49;GAK inhibitor 49;GAK inhibitor 49, 10 mM in DMSO;6,7-Dimethoxy-N-(3,4,5-trimethoxyphenyl)quinolin-4-amine;4-Quinolinamine, 6,7-dimethoxy-N-(3,4,5-trimethoxyphenyl)-;NAK,selective,GAK inhibitor-49,GAK inhibitor49,GAK inhibitor 49,Inhibitor,inhibit,ATP-competitive,family
CBNumber
CB54667925
Molecular Formula
C20H22N2O5
Formula Weight
370.4
MOL File
319492-82-5.mol
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GAK inhibitor 49 Property

Boiling point:
494.8±45.0 °C(Predicted)
Density 
1.223±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO: 50 mg/mL (134.99 mM; ultrasonic and warming and heat to 80°C)
pka
7?+-.0.50(Predicted)
form 
Solid
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Ambeed
Product number
A1359459
Product name
6,7-Dimethoxy-N-(3,4,5-trimethoxyphenyl)quinolin-4-amine
Purity
98%
Packaging
1mg
Price
$39
Updated
2021/12/16
Ambeed
Product number
A1359459
Product name
6,7-Dimethoxy-N-(3,4,5-trimethoxyphenyl)quinolin-4-amine
Purity
98%
Packaging
5mg
Price
$55
Updated
2021/12/16
Ambeed
Product number
A1359459
Product name
6,7-Dimethoxy-N-(3,4,5-trimethoxyphenyl)quinolin-4-amine
Purity
98%
Packaging
10mg
Price
$100
Updated
2021/12/16
Ambeed
Product number
A1359459
Product name
6,7-Dimethoxy-N-(3,4,5-trimethoxyphenyl)quinolin-4-amine
Purity
98%
Packaging
25mg
Price
$170
Updated
2021/12/16
Ambeed
Product number
A1359459
Product name
6,7-Dimethoxy-N-(3,4,5-trimethoxyphenyl)quinolin-4-amine
Purity
98%
Packaging
50mg
Price
$290
Updated
2021/12/16
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GAK inhibitor 49 Chemical Properties,Usage,Production

Uses

GAK inhibitor 49 is a potent, ATP-competitive and highly selective cyclin G associated kinase (GAK) inhibitor with a Ki of 0.54 nM and a cell IC50 of 56 nM. GAK inhibitor 49 also shows binding to RIPK2[1].

References

[1] Asquith CRM, et al. Identification and Optimization of 4-Anilinoquinolines as Inhibitors of Cyclin G Associated Kinase. ChemMedChem. 2018;13(1):48-66. DOI:10.1002/cmdc.201700663

GAK inhibitor 49 Preparation Products And Raw materials

Raw materials

Preparation Products

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GAK inhibitor 49 Suppliers

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319492-82-5, GAK inhibitor 49Related Search:


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  • 6,7-Dimethoxy-N-(3,4,5-trimethoxyphenyl)quinolin-4-amine
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  • GAK inhibitor 49, 10 mM in DMSO
  • 319492-82-5