ChemicalBook > CAS DataBase List > CNT2 inhibitor-1
CNT2 inhibitor-1
- Product Name
- CNT2 inhibitor-1
- CAS No.
- 880155-70-4
- Chemical Name
- CNT2 inhibitor-1
- Synonyms
- CNT2 inhibitor-1;CNT2 inhibitor-1, 10 mM in DMSO;CNT-2 inhibitor-1,CNT2 inhibitor 1,CNT2 inhibitor1;Adenosine, 8-[([1,1'-biphenyl]-4-ylmethyl)amino]- (9CI);(2R,3R,4S,5R)-2-(8-(([1,1'-Biphenyl]-4-ylmethyl)amino)-6-amino-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
- CBNumber
- CB54797039
- Molecular Formula
- C23H24N6O4
- Formula Weight
- 448.47
- MOL File
- 880155-70-4.mol
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CNT2 inhibitor-1 Property
- Boiling point:
- 807.5±75.0 °C(Predicted)
- Density
- 1.57±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO : 75 mg/mL (167.24 mM)
- form
- Solid
- pka
- 13.07±0.70(Predicted)
- color
- Off-white to light yellow
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N-Bromosuccinimide Price
Biorbyt Ltd
- Product number
- orb573219
- Product name
- CNT2 inhibitor-1
- Packaging
- 100mg
- Price
- $2691.1
- Updated
- 2021/12/16
Biorbyt Ltd
- Product number
- orb573219
- Product name
- CNT2 inhibitor-1
- Packaging
- 250mg
- Price
- $5358.4
- Updated
- 2021/12/16
Biorbyt Ltd
- Product number
- orb573219
- Product name
- CNT2 inhibitor-1
- Packaging
- 1g
- Price
- $10693
- Updated
- 2021/12/16
DC Chemicals
- Product number
- DC12103
- Product name
- CNT2inhibitor-1
- Purity
- >98%
- Packaging
- 1g
- Price
- $7200
- Updated
- 2021/12/16
DC Chemicals
- Product number
- DC12103
- Product name
- CNT2inhibitor-1
- Purity
- >98%
- Packaging
- 250mg
- Price
- $3600
- Updated
- 2021/12/16
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CNT2 inhibitor-1 Chemical Properties,Usage,Production
Uses
CNT2 inhibitor-1 is a potent concentrative nucleoside transporter 2 Inhibitor (CNT2), with an IC50 of 640 nM for hCNT2.
Biological Activity
Primary Target
hCNT2', 'Reversible: yes', 'Target IC50: 640 nM in COS-7 cells
References
[1] Tatani K, et al. Identification of 8-aminoadenosine derivatives as a new class of human concentrative nucleoside transporter 2 inhibitors. ACS Med Chem Lett. 2015 Jan 28;6(3):244-8. DOI:10.1021/ml500343r
CNT2 inhibitor-1 Preparation Products And Raw materials
Raw materials
Preparation Products
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