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Schisandrin A

Product Name
Schisandrin A
CAS No.
61281-38-7
Chemical Name
Schisandrin A
Synonyms
WUWEIZISU A;SCHIZANDRIN A;SCHISANDRIN A;Doxyschizandrin;DEOXYSCHISANDRIN;DEOXYSCHIZANDRIN;Schizandrin A-RM;DiMethylgoMisin J;R(+) SCHISANDRIN A;R(+) SCHIZANDRIN A
CBNumber
CB5670585
Molecular Formula
C24H32O6
Formula Weight
416.51
MOL File
61281-38-7.mol
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Schisandrin A Property

Melting point:
116-117 °C
Boiling point:
544.2±50.0 °C(Predicted)
Density 
1.080±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,2-8°C
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
powder
color 
White to Off-White
LogP
5.870 (est)
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Safety

Safety Statements 
24/25
WGK Germany 
3
RTECS 
HP1595000
HS Code 
29093090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SMB00368
Product name
Schisandrin A
Purity
≥98% (HPLC)
Packaging
10mg
Price
$116
Updated
2025/07/31
Sigma-Aldrich
Product number
90139
Product name
Schisandrin A
Purity
analytical standard
Packaging
50mg
Price
$390
Updated
2022/05/15
TCI Chemical
Product number
C3501
Product name
Schisandrin A
Packaging
25MG
Price
$103
Updated
2025/07/31
TCI Chemical
Product number
C3501
Product name
Schisandrin A
Packaging
100MG
Price
$284
Updated
2025/07/31
Cayman Chemical
Product number
19849
Product name
Schisandrin A
Purity
≥98%
Packaging
5mg
Price
$43
Updated
2023/06/20
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Schisandrin A Chemical Properties,Usage,Production

Description

Schisandrin A is a lignan that has been found in Schisandra and has diverse biological activities. It binds to adiponectin receptor 2 (IC50 = 3.2 μM). Schisandrin A (10, 20, and 50 μM) reduces LPS-induced production of nitric oxide (NO), IL-6, and TNF-α and apoptosis in primary mouse microglial cells. It reverses P-glycoprotein-mediated doxorubicin resistance in MCF-7/dox cells when used at a concentration of 20 μM. Schisandrin A (4, 12, and 36 mg/kg) reverses short-term and spatial memory deficits, as well as decreases in cerebral superoxide dismutase (SOD) and glutathione peroxidase (GPX) activities induced by amyloid β (1-42) (Aβ42; ) in a mouse model of Alzheimer’s disease.

Chemical Properties

White powder

Uses

Schizandrin A is an extract from Schisandra chinesis. a dibenzocyclooctadiene lignan with antiinflammatory activity.

in vivo

Schisandrin A (SchA) significantly inhibits CYP3A activity in rat hepatic microsomes and Vmax value of each group in a concentration-dependent manner. The double-reciprocal plots and the secondary plot show that Schisandrin A inhibits CYP3A activity, with an apparent Ki value of 30.67 mg/kg. In each Schisandrin A-treated group, Schisandrin A also significantly decreases 1-hydroxymidazolam plasma concentrations compared with the negative group (to levels similar to the positive group)[2].

IC 50

CYP3A: 6.6 μM (IC50); Autophagy

References

[1] YIYI SUN. Identification of adiponectin receptor agonist utilizing a fluorescence polarization based high throughput assay.[J]. PLoS ONE, 2013: e63354. DOI: 10.1371/journal.pone.0063354
[2] FANG-JIAO SONG. Schizandrin A Inhibits Microglia-Mediated Neuroninflammation through Inhibiting TRAF6-NF-κB and Jak2-Stat3 Signaling Pathways[J]. PLoS ONE, 2016, 11 1. DOI: 10.1371/journal.pone.0149991
[3] ZONG-LIN ZHANG  Su R W  Qing Cheng Jiang. Schisandrin A reverses doxorubicin-resistant human breast cancer cell line by the inhibition of P65 and Stat3 phosphorylation.[J]. Breast Cancer, 2018, 25 2: 233-242. DOI: 10.1007/s12282-017-0821-9
[4] DI HU. Deoxyschizandrin isolated from the fruits of Schisandra chinensis ameliorates Aβ????-induced memory impairment in mice.[J]. Planta medica, 2012, 78 12: 1332-1336. DOI: 10.1055/s-0032-1315019

Schisandrin A Preparation Products And Raw materials

Raw materials

Preparation Products

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Schisandrin A Suppliers

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View Lastest Price from Schisandrin A manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
Schisandrin A 61281-38-7
Price
US $0.10-10.00/KG
Min. Order
0.10000000149011612KG
Purity
98%
Supply Ability
200TONS
Release date
2025-08-15

61281-38-7, Schisandrin ARelated Search:

SCHISANDRIN (SCHISANDROL A),SCHISANDRIN,Schisandrin（Schizandrol A） SCHISANDRIN(SCHISANDROL A)(P),SCHISANDRIN, GAMMA-,S(-)-SCHISANDRIN,S(-) SCHISANDRIN B,GAMMA-SCHISANDRIN,SCHISANDRIN B schisanhenol Baicalin Asiaticoside Silibinin Podophyllotoxin 2-BUTENOIC ACID, 2-METHYL-, (5S,6S,7S,13AS)-5,6,7,13A-TETRAHYDRO-6-HYDROXY-1,2,3,13-TETRAMETHOXY-6,7-DIMETHYLBENZO[3,4]CYCLOOCTA[1,2-F][1,3]BENZODIOXOL-5-YL ESTER, (2Z)- WUWEIZISU C Schisantherin A Gomisin A SCHISANTHERIN C 98+% HPLC Schisandrin C γ-Schisandrin Schisandrin A SCHISANDRIN SNAP-N-SHOOT 0.1mg/mL(P) Schizandra Chinesis (9% Schisandrin) SCHISANDRIN, gamma- SNAP-N-SHOOT 0.1mg/mL(P),SCHISANDRIN, gamma-(AHP)

  • SCHISANDRIN A (DEOXYSCHISANDRIN)
  • SCHISANDRA CHINENSIS PLANT EXTRACT 9+% SCHISANDRINS
  • SCHISANDRA CHINENSIS PLANT EXTRACT 5+% SCHISANDRINS
  • SCHISANDRA PLANT EXTRACT
  • SCHISANDRA BERRY POWDER
  • SCHISANDRIN A, (DEOXYSCHISANDRIN) 98% BY HPLC
  • SCHISANDRA CHINENSIS PLANT EXTRACT 2+% SCHISANDRINS
  • DEOXYSCHIZANDRIN90%,99%
  • SCHISANDRIN A(DEOXYSCHISANDRIN) SNAPN 0.1mg/ml(SH)
  • SCHISANDRIN A(DEOXYSCHISANDRIN)(P)
  • dibenzo(a,c)cyclooctene,5,6,7,8-tetrahydro-6,7-dimethyl-1,2,3,10,11,12-hexamet
  • R(+) DEOXYSCHISANDRIN A
  • R(+) DEOXYSCHIZANDRIN A
  • R(+) SCHISANDRIN A
  • R(+) SCHIZANDRIN A
  • SCHIZANDRIN A
  • SCHISANDRIN A
  • WUWEIZISU A
  • DEOXYSCHISANDRIN
  • DEOXYSCHIZANDRIN
  • (+)-Deoxyschisandrin
  • 1,2,3,10,11,12-hexamethoxy-6,7-dimethyl-,(6R,7S,12aR)-
  • Dibenzo [a,c]cyclooctene,5,6,7,8-tetrahydro-
  • Schisandrin A，Schizandrin A，(+)-Deoxyschisandrin，Deoxyschizandrin
  • (+)-Deoxyschisandrin,Deoxyschizandrin
  • DEOXYSCHIZANDRIN SCHISANDRIN A
  • Deoxyschizandrin, 98%, from magnoliavine P.E
  • Schisandrin A(Deoxyschizandrin)
  • DiMethylgoMisin J
  • Deoxyschizandrin, froM Magnoliavine P.E
  • Doxyschizandrin
  • Schizandrin A (+)-Deoxyschisandrin,Deoxyschizandrin
  • Deoxyschizandrin, 98%, from Schisandra chinensis (Turcz.) Baill.
  • Dibenzo[a,c]cyclooctene, 5,6,7,8-tetrahydro-1,2,3,10,11,12-hexamethoxy-6,7-dimethyl-, (6R,7S,12aR)-
  • (6R,7S,12aR)-5,6,7,8-Tetrahydro-1,2,3,10,11,12-hexamethoxy-6,7-dimethyldibenzo[a,c]cyclooctene
  • Inhibitor,Schisandrin A,Cytochrome P450,Schizandrin-A,Autophagy,Deoxyschizandrin,Virus Protease,inhibit,Wuweizisu-A,Schizandrin A,CYPs
  • Schizandrin A-RM
  • Schizandrin A, 10 mM in DMSO
  • Compound T2926(SC)
  • 61281-38-7
  • Miscellaneous Natural Products
  • Inhibitors
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract