FAMPHUR Property

Melting point:

53℃

Boiling point:

394.2±52.0 °C(Predicted)

Density 

1.354±0.06 g/cm3(Predicted)

vapor pressure 

3 x 10^-5 Pa (est. 20 °C)

Flash point:

>100 °C

storage temp. 

APPROX 4°C

Water Solubility 

5000 (est. 20 °C)

form 

Liquid

pka

-5.18±0.70(Predicted)

Merck 

13,3963

BRN 

2224254

EPA Substance Registry System

Famphur (52-85-7)

Safety

Hazard Codes 

T,Xn,F

Risk Statements 

24/25-36/38-63-43-36/37/38-23/24/25-45-67-40-39/23/24/25-11

Safety Statements 

22-24/25-45-36/37-23-53-16-7

RIDADR 

2783

WGK Germany 

3

RTECS 

TF7650000

HazardClass 

6.1(a)

PackingGroup 

II

HS Code 

29350090

Hazardous Substances Data

52-85-7(Hazardous Substances Data)

Toxicity

LD50 orally in rats: 35 mg/kg (Schafer)

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H300Fatal if swallowed

H311Toxic in contact with skin

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

FAMPHUR Chemical Properties,Usage,Production

Chemical Properties

Crystalline powder. Very soluble in chloroform and carbon tetrachloride; slightly soluble in water.

Uses

Insecticide.

Definition

ChEBI: Famphur is an organic thiophosphate and an organothiophosphate insecticide. It has a role as an EC 3.1.1.7 (acetylcholinesterase) inhibitor, an agrochemical and an anthelminthic drug. It is functionally related to a 4-hydroxy-N,N-dimethylbenzenesulfonamide.

General Description

Crystalline powder. Very toxic. Cholinesterase inhibitor. Restricted use as insecticide.

Air & Water Reactions

Slightly soluble in water.

Reactivity Profile

Organothiophosphates, such as FAMPHUR, are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides.

Hazard

Cholinesterase inhibitor, use may be restricted.

Metabolism

The principal degradation routes in mammals are P?Ophenyl bond cleavage and O-demethylation. Oxidative desulfuration and N-demethylation also take place to form toxic metabolites.

Toxicity evaluation

The acute oral LD₅₀ for rats is 35–62 mg/kg.