ChemicalBook > CAS DataBase List > Dithizone
Dithizone
- Product Name
- Dithizone
- CAS No.
- 60-10-6
- Chemical Name
- Dithizone
- Synonyms
- DIPHENYLTHIOCARBAZONE;dithizon;Dithizone (min. 98%);1,5-diphenyl-3-thiocarbazone;(E)-1,5-diphenylthiocarbazone;Diazenecarbothioic acid, 2-phenyl-, 2-phenylhydrazide;Ditizon;DITHIZONE;usafek-3092;DITHIZONE(P)
- CBNumber
- CB5753569
- Molecular Formula
- C13H12N4S
- Formula Weight
- 256.33
- MOL File
- 60-10-6.mol
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Dithizone Property
- Melting point:
- 168 °C (dec.) (lit.)
- Boiling point:
- 376.1±25.0 °C(Predicted)
- bulk density
- 250kg/m3
- Density
- 1.2578 (rough estimate)
- refractive index
- 1.5700 (estimate)
- storage temp.
- no restrictions.
- solubility
- Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
- form
- Crystalline
- pka
- pK1:4.50;pK2:15 (25°C)
- color
- Black powder
- Water Solubility
- Soluble in ethanol, chloroform, dimethylsulfoxide, and pyridine. Insoluble in water.
- λmax
- 604-607 nm in chloroform
- Merck
- 14,3377
- BRN
- 748838
- Stability:
- Stable. Incompatible with strong oxidizing agents.
- CAS DataBase Reference
- 60-10-6(CAS DataBase Reference)
- EPA Substance Registry System
- Diazenecarbothioic acid, phenyl-, 2-phenylhydrazide (60-10-6)
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Safety
- Hazard Codes
- Xi
- Risk Statements
- 22-36/37/38
- Safety Statements
- 36-26
- RIDADR
- 2811
- WGK Germany
- 3
- RTECS
- LQ9450000
- TSCA
- Yes
- HazardClass
- 6.1
- PackingGroup
- III
- HS Code
- 29309090
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- DX2370
- Product name
- Dithizone
- Purity
- Meets ACS Specifications, Meets Reagent Specifications for testing USP/NF monographs GR ACS
- Packaging
- 25g
- Price
- $1030
- Updated
- 2025/07/31
Sigma-Aldrich
- Product number
- 1.03092
- Product name
- Dithizone
- Purity
- for analysis (1,5-diphenylthiocarbazone) Reag. Ph Eur
- Packaging
- 5G
- Price
- $158
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- 1.03092
- Product name
- Dithizone
- Purity
- for analysis (1,5-diphenylthiocarbazone) Reag. Ph Eur
- Packaging
- 25g
- Price
- $396
- Updated
- 2024/03/01
TCI Chemical
- Product number
- D0949
- Product name
- Dithizone
- Purity
- >85.0%(E)
- Packaging
- 25g
- Price
- $97
- Updated
- 2025/07/31
Sigma-Aldrich
- Product number
- D5130
- Product name
- Dithizone
- Purity
- Practical Grade
- Packaging
- 10g
- Price
- $85
- Updated
- 2025/07/31
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Dithizone Chemical Properties,Usage,Production
Chemical Properties
dark brown or black crystals
Uses
Dithizone is an organosulfur compound that acts as a chelating agent and forms complexes with metals such as lead and mercury. Dithizone is used to assess the purity of human pancreatic islet preparations used for transplantation into patients with type 1 diabetes.
Uses
Dithizone is used as an indicator for minute amounts of lead. It acts as a chelating agent for heavy metal poisoning. As a ligand, it forms complexes with metals like zinc, lead and mercury. Further, it is used to assess the purity of human pancreatic islet preparations, which is used for transplantation in patients with type 1 diabetes. In addition to this, it is used as a titrant in the quantitative determination of heavy metals.
Uses
Sensitive reagent for several heavy metals, Co, Cu, Pb, and Hg; especially for the estimation of minute amounts of Pb.
Definition
ChEBI: Dithizone is a member of phenylhydrazines.
General Description
Dithizone (Diphenylthiocarbazone) is used as chelating agent for zinc. It is widely used for the liquid-liquid and solid phase extraction of various metals since it forms stable complexes with the metals.
Purification Methods
The crude dithizone is dissolved in CCl4 to give a concentrated solution. This is filtered through a sintered glass funnel and shaken with 0.8M aqueous ammonia to extract dithizonate ion. The aqueous layer is washed with several portions of CCl4 to remove undesirable materials. The aqueous layer is acidified with dilute H2SO4 to precipitate pure dithizone. This is dried in a vacuum. When only small amounts of dithizone are required, purification by paper chromatography is convenient. [Cooper & Hibbits J Am Chem Soc 75 5084 1933.] Instead of CCl4, CHCl3 can be used, and the final extract, after washing with water, can be evaporated in air at 40-50o and dried in a desiccator. It complexes with Cd, Hg, Ni and Zn. [Beilstein 16 H 26, 16 IV 18.]
Dithizone Preparation Products And Raw materials
Raw materials
Hydrogen Sulfide
Diphenyl
4-Chlorobenzaldehyde
Potassium hydroxide
Congo red paper
Thiocarbohydrazide
Methanol
Preparation Products
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View Lastest Price from Dithizone manufacturers
Hebei Chuanghai Biotechnology Co., Ltd
- Product
- Dithizone 60-10-6
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-11-21
Watson Biotechnology Co.,Ltd
- Product
- Dithizone 60-10-6
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 80%
- Supply Ability
- 20MT
- Release date
- 2024-08-14
R&D Scientific Inc.
- Product
- Dithizone 60-10-6
- Price
- US $250.00/g
- Min. Order
- 1g
- Purity
- 96
- Supply Ability
- 500 Kg
- Release date
- 2024-02-18
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