YAP-TEAD-IN-1 TFA

Product Name: YAP-TEAD-IN-1 TFA
CAS No.: 1659305-79-9
Chemical Name: YAP-TEAD-IN-1 TFA
Synonyms: YAP-TEAD-IN-1 TFA;YAP-TEAD (Peptide 17).TFA;(S)-4-((S)-1-((S)-1-((S)-2-((3S,6S,9S,12R,18S,21S,24S,27S,30S,35AS)-18-((S)-2-((S)-1-((S)-2-Acetamido-3-methylbutanoyl)pyrrolidine-2-carboxamido)-3-(3-chlorophenyl)propanamido)-27-(4-aminobutyl)-9-benzyl-30-butyl-24-(3-guanidinopropyl)-6-(hydroxymethyl)-21-isobutyl-3-methyl-1,4,7,10,19,22,25,28,31-nonaoxodotriacontahydro-1H-pyrrolo[2,1-p][1,2,5,8,11,14,17,20,23,26,29]dithianonaazacyclotritriacontine-12-carboxamido)-6-aminohexanoyl)pyrrolidine-2-carbonyl)pyrrolidine-2-carboxamido)-5-amino-5-oxope
CBNumber: CB58053647
Molecular Formula: C95H145ClF3N23O23S2
Formula Weight: 2133.91
MOL File: 1659305-79-9.mol

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YAP-TEAD-IN-1 TFA Property

storage temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility: Soluble in DMSO
form: Solid
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0116209
Product name: YAP-TEAD-IN-1(TFA)
Purity: 99.88%
Packaging: 1mg
Price: $180
Updated: 2021/12/16

ChemScene

Product number: CS-0116209
Product name: YAP-TEAD-IN-1(TFA)
Purity: 99.88%
Packaging: 5mg
Price: $420
Updated: 2021/12/16

ChemScene

Product number: CS-0116209
Product name: YAP-TEAD-IN-1(TFA)
Purity: 99.88%
Packaging: 10mg
Price: $700
Updated: 2021/12/16

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YAP-TEAD-IN-1 TFA Chemical Properties,Usage,Production

Biological Activity

YAP-TEAD-IN-1 TFA is a potent and competitive peptide inhibitor of YAP-TEAD interaction (IC50=25 nM). YAP-TEAD-IN-1 TFA is a 17mer polypeptide with higher binding affinity to TEAD1 (Kd=15 nM) than YAP (50-171) (Kd=40 nM).

in vitro

YAP-TEAD-IN-1 (peptide 17)(2 μM) is against endogenous YAP binding to GST-TEAD(1209-426) in a GST pull-down assay, the K _{d < /sub> of His-YAP(1209-426) is determined to be 40 nM.}

target

IC50: 25 nM (YAP-TEAD interaction)

YAP-TEAD-IN-1 TFA Preparation Products And Raw materials

Raw materials

Preparation Products

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YAP-TEAD-IN-1 TFA Suppliers

China 11 United States 2 Global 13

Shanghai Chaolan Chemical Technology Center

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RD International Technology Co., Limited

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1659305-79-9, YAP-TEAD-IN-1 TFARelated Search:

YAP-TEAD-IN-1 TFA

YAP-TEAD (Peptide 17).TFA

(S)-4-((S)-1-((S)-1-((S)-2-((3S,6S,9S,12R,18S,21S,24S,27S,30S,35AS)-18-((S)-2-((S)-1-((S)-2-Acetamido-3-methylbutanoyl)pyrrolidine-2-carboxamido)-3-(3-chlorophenyl)propanamido)-27-(4-aminobutyl)-9-benzyl-30-butyl-24-(3-guanidinopropyl)-6-(hydroxymethyl)-21-isobutyl-3-methyl-1,4,7,10,19,22,25,28,31-nonaoxodotriacontahydro-1H-pyrrolo[2,1-p][1,2,5,8,11,14,17,20,23,26,29]dithianonaazacyclotritriacontine-12-carboxamido)-6-aminohexanoyl)pyrrolidine-2-carbonyl)pyrrolidine-2-carboxamido)-5-amino-5-oxope

1659305-79-9