K114

Product Name: K114
CAS No.: 872201-12-2
Chemical Name: K114
Synonyms: K114;K114,K-114;(trans,trans)-1-bromo-2,5-bis-(4-hydroxy)styrylbenzene;K114,(trans,trans)-1-Bromo-2,5-bis-(4-hydroxy)styrylbenzene;4,4'-[(2-Bromo-1,4-phenylene)di-(1E)-2,1-ethenediyl]bisphenol;Phenol, 4,4'-[(2-bromo-1,4-phenylene)di-(1E)-2,1-ethenediyl]bis-;4,4'-((1E,1'E)-(2-bromo-1,4-phenylene)bis(ethene-2,1-diyl))diphenol
CBNumber: CB5972713
Molecular Formula: C22H17BrO2
Formula Weight: 393.27
MOL File: 872201-12-2.mol

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K114 Property

Boiling point:: 563.0±39.0 °C(Predicted)
Density: 1.462±0.06 g/cm3(Predicted)
storage temp.: Store at +4°C
solubility: DMSO: soluble >10mg/mL
form: powder
pka: 9.92±0.26(Predicted)
color: white to beige

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Safety

Hazard Codes: Xi
Risk Statements: 36
Safety Statements: 26
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H319Causes serious eye irritation

H413May cause long lasting harmful effects to aquatic life

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Tocris

Product number: 3144
Product name: K114
Purity: ≥98%(HPLC)
Packaging: 10
Price: $123
Updated: 2021/12/16

Tocris

Product number: 3144
Product name: K114
Purity: ≥98%(HPLC)
Packaging: 50
Price: $515
Updated: 2021/12/16

TRC

Product number: K000450
Product name: K114
Packaging: 10mg
Price: $95
Updated: 2021/12/16

Usbiological

Product number: 255576
Product name: K 114
Packaging: 10mg
Price: $366
Updated: 2021/12/16

ChemScene

Product number: CS-0027952
Product name: K114
Purity: >99.0%
Packaging: 2mg
Price: $110
Updated: 2021/12/16

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K114 Chemical Properties,Usage,Production

Description

K 114 is a potent amyloid fibril-specific fluorescent dye (EC50 = 20-30 nM).

Uses

K 114 is a potent amyloid fibril-specific fluorescent dye. K 114 is a potent amyloid fibril-specific fluorescent dye similar to Congo Red and BSB. K 114 recognizes amyloid lesions and facilitates quantitative monitoring of the formation of amyloid fibrils assembled from the Aβ peptide, α-synuclein, and tau. The affinity for fibrils ranges 20-30 nM. Unlike the other compounds K114 has minimal fluorescence in aqueous buffers, but fluoresces brightly in the presence of amyloid fibrils. K114 can be used to monitor in vitro amyloid fibril formation by fluorescence emission at 550 nm.

Definition

ChEBI: (E,E)-1-bromo-2,5-bis-(4-hydroxystyryl)benzene is an organobromine compound that is bromobenzene in which the hydrogens at positions 2 and 5 are replaced by 4-hydroxystyryl groups. It has a role as a fluorescent dye. It is an organobromine compound and a polyphenol.

Biological Activity

Potent amyloid fibril-specific fluorescent dye (EC 50 = 20 - 30 nM). Exhibits minimal fluorescence in aqueous buffers and fluoresces brightly in the presence of A β , α -synuclein and tau in situ . (Optimum wavelength = 550 nM).

storage

Store at +4°C

K114 Preparation Products And Raw materials

Raw materials

Preparation Products

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K114 Suppliers

China 29 Switzerland 1 United Kingdom 1 United States 8 Global 39

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15838
Advantage: 69

Nanjing Chemlin Chemical Co., Ltd

Tel: 025-83697070
Fax: +86-25-83453306
Email: info@chemlin.com.cn
Country: China
ProdList: 15883
Advantage: 64

Wuhan TCASChem Technology Co., Ltd.

Tel: 027-86697669 13986148687
Fax: 86-027-86697669
Email: sales@tcaschem.com
Country: China
ProdList: 4001
Advantage: 55

EMMX Biotechnology LLC

Tel: 888-539-0666
Fax: 888-539-0666
Email: info@emmx.com
Country: United States
ProdList: 8447
Advantage: 60

Shanghai Chaolan Chemical Technology Center

Tel: 021-QQ：65489617 15618227136
Fax: 21-5161 9052
Email: Sales@ATKchemical.com
Country: China
ProdList: 9119
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32435
Advantage: 58

ShangHai ChuanQian Chemcial Technique Centre

Tel: 15869524721
Email: 3525679403@qq.com
Country: China
ProdList: 4989
Advantage: 58

MedBioPharmaceutical Technology Inc

Tel: 021-69568360 18916172912
Email: order@med-bio.cn
Country: China
ProdList: 8140
Advantage: 58

Shenzhen Shengda Pharmaceutical co Limited

Tel: 0755-85269922 13424394241
Fax: QQ:1799060443
Email: sales@shengdapharm.com
Country: China
ProdList: 505
Advantage: 58

Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 15801484223;
Email: psaitong@jm-bio.com
Country: China
ProdList: 29757
Advantage: 58

872201-12-2, K114Related Search:

K114,(trans,trans)-1-Bromo-2,5-bis-(4-hydroxy)styrylbenzene

(trans,trans)-1-bromo-2,5-bis-(4-hydroxy)styrylbenzene

K114

4,4'-[(2-Bromo-1,4-phenylene)di-(1E)-2,1-ethenediyl]bisphenol

Phenol, 4,4'-[(2-bromo-1,4-phenylene)di-(1E)-2,1-ethenediyl]bis-

K114,K-114

4,4'-((1E,1'E)-(2-bromo-1,4-phenylene)bis(ethene-2,1-diyl))diphenol

872201-12-2