Benzenamine, 2-ethynyl-4-methyl- (9CI)
- Product Name
- Benzenamine, 2-ethynyl-4-methyl- (9CI)
- CAS No.
- 215589-37-0
- Chemical Name
- Benzenamine, 2-ethynyl-4-methyl- (9CI)
- Synonyms
- Benzenamine, 2-ethynyl-4-methyl-;2-Ethynyl-4-methylaniline - [E51676];Benzenamine, 2-ethynyl-4-methyl- (9CI)
- CBNumber
- CB61061981
- Molecular Formula
- C9H9N
- Formula Weight
- 131.17
- MOL File
- 215589-37-0.mol
Benzenamine, 2-ethynyl-4-methyl- (9CI) Property
- Boiling point:
- 241.8±33.0 °C(Predicted)
- Density
- 1.03±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C(protect from light)
- form
- solid
- pka
- 2.44±0.10(Predicted)
N-Bromosuccinimide Price
- Product number
- RNI00125
- Product name
- 2-Ethynyl-4-methylaniline
- Packaging
- 1g
- Price
- $216
- Updated
- 2025/07/31
- Product number
- 054238
- Product name
- 2-Ethynyl-4-methylaniline
- Purity
- >95%
- Packaging
- 500mg
- Price
- $300
- Updated
- 2021/12/16
- Product number
- AS114225
- Product name
- 2-Ethynyl-4-methylaniline
- Purity
- 97+%
- Packaging
- 250mg
- Price
- $324
- Updated
- 2021/12/16
- Product number
- 054238
- Product name
- 2-Ethynyl-4-methylaniline
- Purity
- >95%
- Packaging
- 1g
- Price
- $347
- Updated
- 2021/12/16
- Product number
- E51676
- Product name
- 2-Ethynyl-4-methylaniline
- Purity
- 95+%
- Packaging
- 100mg
- Price
- $70
- Updated
- 2021/12/16
Benzenamine, 2-ethynyl-4-methyl- (9CI) Chemical Properties,Usage,Production
Synthesis
180624-14-0
215589-37-0
General procedure for the synthesis of 2-ethynyl-4-methylaniline from the compound (CAS: 180624-14-0): to a stirred 2:1 MeOH/Et2O (250 mL) solution of 2-ethynyl-4-methylaniline (22) (11.32 g, 55.6 mmol) was added, at room temperature, K2CO3 (15.38 g, 111 mmol ). After stirring at this temperature for 1 h, the reaction mixture was diluted with water and extracted with CH2Cl2. The organic layer was dried over MgSO4, filtered and concentrated under reduced pressure to afford 2-alkynyl-4-methylaniline (23) as a light brown solid without further purification (6.79 g, 93%).1H NMR (300 MHz, CDCl3) δ 7.14 (d, J = 1.5 Hz, 1H), 6.96 (dd, J = 8.2, 1.5 Hz, 1H), 6.62 (d, J = 8.2, 1.5 Hz, 1H) 6.62 (d, J = 8.2 Hz, 1H), 4.11 (s, 2H), 3.36 (s, 1H), 2.21 (s, 3H).
References
[1] Patent: US2014/31559, 2014, A1. Location in patent: Paragraph 0272
[2] Journal of Organic Chemistry, 2006, vol. 71, # 9, p. 3653 - 3655
[3] Synlett, 2006, # 1, p. 65 - 68
[4] Angewandte Chemie - International Edition, 2007, vol. 46, # 12, p. 2074 - 2077
[5] Journal of Organic Chemistry, 2008, vol. 73, # 11, p. 4160 - 4165
Benzenamine, 2-ethynyl-4-methyl- (9CI) Preparation Products And Raw materials
Raw materials
Preparation Products
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