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Solifenacin Hydrochloride

Product Name
Solifenacin Hydrochloride
CAS No.
180468-39-7
Chemical Name
Solifenacin Hydrochloride
Synonyms
Solifenacin HCl;YM905 hydrochloride;YM 905 hydrochloride;YM-905 hydrochloride;Vesicare hydrochloride;Solifenacin Succinate 3;Solifenacin Hydrochloride;VESICARE HYDROCHLORIDE;YM905 HYDROCHLORIDE;YM 905 HYDROCHLORIDE;YM-905 HYDROCHLORIDE;(1S)-3,4-Dihydro-1-phenyl-2(1H)-isoquinolinecarboxylic Acid (3R)-1-Azabicyclo-[2.2.2]oct-3-yl Ester Hydrochlorid;(1S)-3,4-Dihydro-1-phenyl-2(1H)-isoquinolinecarboxylic Acid (3R)-1-Azabicyclo-[2.2.2]oct-3-yl Ester Hydrochloride
CBNumber
CB61176791
Molecular Formula
C23H27ClN2O2
Formula Weight
398.93
MOL File
180468-39-7.mol
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Solifenacin Hydrochloride Property

Melting point:
120-122°C
storage temp. 
Hygroscopic, -20°C Freezer, Under Inert Atmosphere
solubility 
DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly)
form 
Solid
color 
White to Off-White
Stability:
Hygroscopic
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
S676700
Product name
SolifenacinHydrochloride
Packaging
5mg
Price
$130
Updated
2021/12/16
Usbiological
Product number
289163
Product name
Solifenacin hydrochloride
Packaging
5mg
Price
$460
Updated
2021/12/16
ChemScene
Product number
CS-2661
Product name
Solifenacin(hydrochloride)
Purity
99.29%
Packaging
5mg
Price
$100
Updated
2021/12/16
ApexBio Technology
Product number
B3415
Product name
Solifenacinhydrochloride
Packaging
100mg
Price
$116
Updated
2021/12/16
ChemScene
Product number
CS-2661
Product name
Solifenacin(hydrochloride)
Purity
99.29%
Packaging
10mg
Price
$150
Updated
2021/12/16
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Solifenacin Hydrochloride Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

Muscarinic M3 receptor antagoinst used in treatment of urinary incontinence.

Uses

Solifenacin Hydrochloride can be used as muscarinic M3 receptor antagoinst and used in treatment of urinary incontinence

in vivo

Solifenacin hydrochloride (YM905 hydrochloride) reduces bladder responses by 40% at a dose of 210 nmol/kg (0.1 mg/kg) and abolishes them at 2100 nmol/kg (1 mg/kg). In contrast, its inhibitory effects on salivary and cardiac responses are only slight at 630 nmol/kg (0.3 mg/kg), and reach 66% and 49%, respectively, at 2100 nmol/kg (1 mg/kg). At doses of 63 and 210 nmol/kg (0.03 and 0.1 mg/kg), Solifenacin hydrochloride slightly increases saliva secretion[1]. Solifenacin hydrochloride (0.01 to 0.3 mg/kg i.v.) dose-dependently increases bladder capacity and voided volume at doses of 0.03 mg/kg i.v. or more, but does not affect residual volume or micturition pressure at any dose tested[2].

IC 50

mAChR2; mAChR1; mAChR3

Solifenacin Hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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Solifenacin Hydrochloride Suppliers

Canada 1 China 35 India 2 South Korea 1 United Kingdom 1 United States 10 Global 50
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
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China
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Chemsky（shanghai）International Co.,Ltd.
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021-50135380
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shchemsky@sina.com
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China
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Haoyuan Chemexpress Co., Ltd.
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021-58950125
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(86) 21-58955996
Email
info@chemexpress.com
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China
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ShangHai Caerulum Pharma Discovery Co., Ltd.
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18149758185
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sales-cpd@caerulumpharma.com
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China
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LETOPHARM LIMITED
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+86-21-5821 5861
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+86-21-5106 2861
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sales@letopharm.com
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China
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Guangzhou QiYun Biotechnology Co., Ltd.
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020-61288194 61288195
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020-61288700
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505721671@qq.com
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China
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Shanghai YuanYe Biotechnology Co., Ltd.
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021-61312847; 18021002903
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QQ:3008007432
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3008007409@qq.com
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China
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Tonichem Pharmaceutical Technology Co., Ltd.
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+86 (0752) 222-7171, +86 15815821171
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+86 (0752) 222-6171
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China
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Roark Standards
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0755-83552066 15986688328
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0755-83552066
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service@roarkstandards.com
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Amadis Chemical Company Limited
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571-89925085
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0086-571-89925065
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sales@amadischem.com
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Shenzhen Polymeri Biochemical Technology Co., Ltd.
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+86-400-002-6226 +86-13028896684;
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sales@rrkchem.com
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Fan De(Beijing) Biotechnology Co., Ltd.
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15911056312
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liming@bio-fount.com
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ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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18818260767
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QQ 3610331285
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sales@chemegen.com
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MedBioPharmaceutical Technology Inc
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021-69568360 18916172912
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order@med-bio.cn
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Energy Chemical
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021-58432009 400-005-6266
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marketing@energy-chemical.com
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Abmole Bioscience Inc.
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021-50967598 02150967598
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sales@abmole.cn
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Beijing Jin Ming Biotechnology Co., Ltd.
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010-60605840 15801484223;
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psaitong@jm-bio.com
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Foshan Treasure Biotechnology Co., Ltd
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0757-85921206 18520245316
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2329783215@qq.com
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Yancheng Tongming Biotechnology Co., Ltd.
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15195160625
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2863565288@qq.com
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TargetMol Chemicals Inc.
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4008200310
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marketing@tsbiochem.com
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Shanghai Tachizaki Biomedical Research Center
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Nanjing Shizhou Biology Technology Co.,Ltd
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Biosynth Biological Technology (Suzhou) Co Ltd
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51288865780
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Santa Cruz Biotechnology Inc
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GIHI CHEMICALS CO.,LIMITED
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Guangzhou Qingyan Biotechnology Co., Ltd.
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Guangzhou Ruifeng Biotechnology Co., Ltd.
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Guangzhou Tuoshan Biotechnology Co., Ltd.
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Absin Bioscience Inc.
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Guangzhou Weijia Technology Co., Ltd.
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Shanghai Hao Biological Technology Co., Ltd.
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Saitong Biotechnology (Shanghai) Co., Ltd.
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Shanghai Hao Zhun Biological Technology Co., Ltd.
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180468-39-7, Solifenacin HydrochlorideRelated Search:

Solifenacin (R)-(-)-3-Quinuclidinol Solifenacin Hydrochloride SOLIFENACIN (1S)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline Solifenacin-D5 Hydrochloride

  • Vesicare hydrochloride
  • VESICARE HYDROCHLORIDE;YM905 HYDROCHLORIDE;YM 905 HYDROCHLORIDE;YM-905 HYDROCHLORIDE
  • YM 905 hydrochloride
  • YM905 hydrochloride
  • YM-905 hydrochloride
  • (1S)-3,4-Dihydro-1-phenyl-2(1H)-isoquinolinecarboxylic Acid (3R)-1-Azabicyclo-[2.2.2]oct-3-yl Ester Hydrochlorid
  • (1S)-3,4-Dihydro-1-phenyl-2(1H)-isoquinolinecarboxylic acid (3R)-1-azabicyclo[2.2.2]oct-3-yl ester hydrochloride (1:1)
  • Solifenacin Hydrochloride
  • (1S)-3,4-Dihydro-1-phenyl-2(1H)-isoquinolinecarboxylic Acid (3R)-1-Azabicyclo-[2.2.2]oct-3-yl Ester Hydrochloride
  • Solifenacin Succinate 3
  • Solifenacin HCl
  • 180468-39-7
  • C23H27ClN2O2
  • Intermediates & Fine Chemicals
  • Pharmaceuticals