Beinaglutide
- Product Name
- Beinaglutide
- CAS No.
- 123475-27-4
- Chemical Name
- Beinaglutide
- Synonyms
- Benaglutide;Beinaglutide;L-Arginine, L-histidyl-L-alanyl-L-α-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-valyl-L-seryl-L-seryl-L-tyrosyl-L-leucyl-L-α-glutamylglycyl-L-glutaminyl-L-alanyl-L-alanyl-L-lysyl-L-α-glutamyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-tryptophyl-L-leucyl-L-valyl-L-lysylglyc...;L-Arginine, L-histidyl-L-alanyl-L-α-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-valyl-L-seryl-L-seryl-L-tyrosyl-L-leucyl-L-α-glutamylglycyl-L-glutaminyl-L-alanyl-L-alanyl-L-lysyl-L-α-glutamyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-tryptophyl-L-leucyl-L-valyl-L-lysylglycyl-
- CBNumber
- CB612030916
- Molecular Formula
- C149H225N39O46
- Formula Weight
- 3298.67
- MOL File
- 123475-27-4.mol
Beinaglutide Property
- Density
- 1.47±0.1 g/cm3(Predicted)
- form
- Solid
- color
- White to off-white
- InChIKey
- NGJOFQZEYQGZMB-BTCPGPLDNA-N
Beinaglutide Chemical Properties,Usage,Production
Uses
Beinaglutide is a human GLP-1 polypeptide that shares almost 100% homology with human GLP-1 (7–36). Beinaglutide displays does-dependent effects in glycemic control, inhibiting food intake and gastric empty and promoting weight loss. Beinaglutide has the potential for the research of overweight/obesity and nonalcoholic steatohepatitis (NASH)[1][2].
in vivo
Beinaglutide (0.6, 1.2, 2.4 mg/kg; s.c.; three times per day for 7 consecutive days) shows the ability of glycemic contro, inhibits food intake and weight loss in mouse[1].
Beinaglutide (150 μg/kg; s.c.; daily for 6 weeks) increases insulin sensitivity of adipocytes[2].
| Animal Model: | Wild-type male C57BL/6 mice and Male Lepob/Lepob (ob/ob) mice (ob/ob-NASH mouse model was induced by GAN diet)[1] |
| Dosage: | 0.6, 1.2, 2.4 mg/kg |
| Administration: | S.c.; three times per day for 7 consecutive days |
| Result: | Significantly reduced blood glucose with dosedependence in C57BL/6 and ob/ob mice, dose dependently inhibits food intake and gastric Emptying, and significantly reduced body weight, food intake with dose-dependence. |
| Animal Model: | Eight-week-old male C57BL/6 mice[2] |
| Dosage: | 150 μg/kg |
| Administration: | S.c.; daily for 6 weeks |
| Result: | Showed improved glucose tolerance and insulin sensitivity, decreased adipose tissue weight and adipocyte size and potentiated insulin sensitivity of adipocytes. |
References
[1] Fang X, et al. Beinaglutide shows significantly beneficial effects in diabetes/obesity-induced nonalcoholic steatohepatitis in ob/ob mouse model. Life Sci. 2021 Apr 1;270:118966. DOI:10.1016/j.lfs.2020.118966
[2] Zhang F, et al. Recombinant human GLP-1 beinaglutide regulates lipid metabolism of adipose tissues in diet-induced obese mice. iScience. 2021 Oct 30;24(12):103382. DOI:10.1016/j.isci.2021.103382
Beinaglutide Preparation Products And Raw materials
Raw materials
Preparation Products
Beinaglutide Suppliers
- Tel
- 1-631-485-4226; 16314854226
- info@bocsci.com
- Country
- United States
- ProdList
- 12952
- Advantage
- 65
- Tel
- tp@aladdinsci.com
- Country
- United States
- ProdList
- 52923
- Advantage
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View Lastest Price from Beinaglutide manufacturers
- Product
- Beinaglutide 123475-27-4
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98
- Supply Ability
- 10000KGS
- Release date
- 2025-11-21
- Product
- Beinaglutide 123475-27-4
- Price
- US $20.00/box
- Min. Order
- 1box
- Purity
- 99
- Supply Ability
- in stock
- Release date
- 2025-07-24
- Product
- Beinaglutide 123475-27-4
- Price
- US $5.00/Box
- Min. Order
- 1Box
- Purity
- 99.99%
- Supply Ability
- 20000 boxes
- Release date
- 2025-07-10