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Dimethylamine hydrochloride

Product Name
Dimethylamine hydrochloride
CAS No.
506-59-2
Chemical Name
Dimethylamine hydrochloride
Synonyms
METHANAMINE HYDROCHLORIDE;DMACl;DIMETHYLAMINE HCL;DIMETHYLAMMONIUM CHLORIDE;DiMethylaMine hydrochlorid;Metformin EP Impurity F HCl;JACS-506-59-2;Dimethylamine hydroc;Imatinib EP Impurity I;Dimethylammoniumchlorid
CBNumber
CB6140366
Molecular Formula
C2H8ClN
Formula Weight
81.54
MOL File
506-59-2.mol
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Dimethylamine hydrochloride Property

Melting point:
170-173 °C(lit.)
Boiling point:
95.79°C (rough estimate)
Density 
0.8949 (rough estimate)
vapor pressure 
<0.1 hPa (25 °C)
refractive index 
1.4202 (estimate)
storage temp. 
Store below +30°C.
solubility 
H2O: soluble0.5g/10 mL
form 
Crystalline Powder or Crystals
color 
White to off-white
PH
5 (100g/l, H2O, 20℃)
Water Solubility 
3000 g/L (20 ºC)
Sensitive 
Hygroscopic
Merck 
14,3228
BRN 
3589311
Stability:
Stable. Incompatible with strong oxidizing agents.
InChIKey
IQDGSYLLQPDQDV-UHFFFAOYSA-N
CAS DataBase Reference
506-59-2(CAS DataBase Reference)
EPA Substance Registry System
Methanamine, N-methyl-, hydrochloride (506-59-2)
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Safety

Hazard Codes 
Xn
Risk Statements 
22-36/37/38
Safety Statements 
26-36/37-37/39-36
WGK Germany 
1
RTECS 
IQ0220000
3-9
TSCA 
Yes
HS Code 
29211190
Toxicity
LD50 in mice (g/kg): 1.21 i.v., 2.00 s.c. (Hazard); LC50 in mice (ppm): 7650 (48 hr), 4725 (14 day); in rats (ppm): 4540 (6 hr) (Steinhagen)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
126365
Product name
Dimethylamine hydrochloride
Purity
99%
Packaging
5g
Price
$18.3
Updated
2021/12/16
Sigma-Aldrich
Product number
8.03052
Product name
Dimethylammonium chloride
Purity
for synthesis
Packaging
5 g
Price
$18.41
Updated
2021/12/16
Sigma-Aldrich
Product number
8.03052
Product name
Dimethylammonium chloride
Purity
for synthesis
Packaging
250 g
Price
$31.63
Updated
2021/12/16
Sigma-Aldrich
Product number
8.03052
Product name
Dimethylammonium chloride
Purity
for synthesis
Packaging
1 kg
Price
$72.98
Updated
2021/12/16
Sigma-Aldrich
Product number
126365
Product name
Dimethylamine hydrochloride
Purity
99%
Packaging
1kg
Price
$76.1
Updated
2021/12/16
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Dimethylamine hydrochloride Chemical Properties,Usage,Production

Chemical Properties

white crystals

Uses

Dimethylamine hydrochloride is a precursor to several industrially significant compounds.

Uses

As accelerator in vulcanizing rubber, tanning, manufacture of detergent soaps, or attracting boll weevils to exterminate them. As reagent for Mg.

Uses

Dimethylamine hydrochloride is used as an intermediate in the manufacture of pharmaceuticals like ranitidine and metformin, tramadol and amlodipine. It is used as a precursor of atrazine. It is associated with sodium acetate and used to carry out the Willgerodt- Kindler reaction to prepare amides. Its free base reacts with carbon disulfide to get dimethyldithiocarbamate which is used in rubber vulcanization. It is involved in the synthesis of dimethyl-(1-methyl-pyrrol-2-ylmethyl)-amine by reacting with 1-methyl pyrrole and formaldehyde.

Application

Dimethylamine hydrochloride is a raw material for organic synthesis. It is also used as a catalyst and magnesium reagent for acetylation analysis.
Dimethylamine hydrochloride has been used in the preparation of hexamethylmelamine-methyl-14C. It has also been used to prepare the standard solution of methylamine (MA), dimethylamine (DMA), trimethylamine (TMA), and trimethylamine-N-oxide (TMAO) while determing methylamines and trimethylamine-N-oxide in particulate matter. Dimethylamine hydrochloride is used as an intermediate in the manufacture of pharmaceuticals like ranitidine and metformin, amlodipine. It is used as a precursor of atrazine. It is associated with sodium acetate and used to carry out the Willgerodt- Kindler reaction to prepare amides. Its free base reacts with carbon disulfide to get dimethyldithiocarbamate which is used in rubber vulcanization. It is involved in the synthesis of dimethyl-(1-methyl-pyrrol-2-ylmethyl)-amine by reacting with 1-methyl pyrrole and formaldehyde.

Purification Methods

Crystallise the salt from hot CHCl3 or absolute EtOH. It also recrystallises from MeOH/ether solution. Dry it in a vacuum desiccator over H2SO4, then P2O5. Hygroscopic. [Beilstein 4 IV 132.]

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Dimethylamine hydrochloride Suppliers

Pure Chemistry Scientific Inc.
Tel
001-857-928-2050 or 1-888-588-9418
Fax
001-617-206-9595
Email
sales@chemreagents.com
Country
United States
ProdList
9917
Advantage
62
BOC Sciences
Tel
16314854226
Email
info@bocsci.com
Country
United States
ProdList
21113
Advantage
65
HBCChem, Inc.
Tel
+1-510-219-6317
Fax
+1-650-486-1361
Email
sales@hbcchem.com
Country
United States
ProdList
10657
Advantage
60
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
19231
Advantage
58
Standardpharm Co. Ltd.
Tel
86-714-3992388
Email
overseasales1@yongstandards.com
Country
United States
ProdList
14344
Advantage
58
Alchem Pharmtech,Inc.
Tel
8485655694
Email
sales@alchempharmtech.com
Country
United States
ProdList
63726
Advantage
58
Cato Research Chemicals Inc.
Tel
020-81215950 4000-868-328
Email
customer@uwalab.com
Country
United States
ProdList
10423
Advantage
58
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View Lastest Price from Dimethylamine hydrochloride manufacturers

Shanxi Lianxu New Material Co., LTD
Product
Dimethylamine hydrochloride 506-59-2
Price
US $30.00/KG
Min. Order
1KG
Purity
99.9%
Supply Ability
1000kg/month
Release date
2021-10-27
Wuhan Aoliqisi New Material Technology Co., Ltd.
Product
Dimethylamine hydrochloride 506-59-2
Price
US $30.00/g
Min. Order
1000g
Purity
99%
Supply Ability
20ton/month
Release date
2021-07-09
Wuhan Aoliqisi New Material Technology Co., Ltd.
Product
Dodecylpyridine hydrochloride 506-59-2
Price
US $10.00/g
Min. Order
10g
Purity
99%
Supply Ability
10000kgs/month
Release date
2021-07-08

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