ChemicalBook > CAS DataBase List > EPIROSMANOL
EPIROSMANOL
- Product Name
- EPIROSMANOL
- CAS No.
- 93380-12-2
- Chemical Name
- EPIROSMANOL
- Synonyms
- EPIROSMANOL;Epirosmanol, 10 mM in DMSO;6β,20-Epoxy-7β,11,12-trihydroxyabieta-8,11,13-triene-20-one;(4aR)-1,3,4,9,10,10aα-Hexahydro-5,6,9β-trihydroxy-1,1-dimethyl-7-(1-methylethyl)-2H-10β,4aβ-(epoxymethano)phenanthren-12-one;2H-10,4a-(Epoxymethano)phenanthren-12-one, 1,3,4,9,10,10a-hexahydro-5,6,9-trihydroxy-1,1-dimethyl-7-(1-methylethyl)-, (4aR,9R,10S,10aS)-;Epirosmanol,inhibit,melanoma cells,scavenging activity,melanin,Inhibitor,antioxidant,diterpene lactone,S. officinalis,DPPH radical,anti-tumor
- CBNumber
- CB61427891
- Molecular Formula
- C20H26O5
- Formula Weight
- 346.42
- MOL File
- 93380-12-2.mol
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EPIROSMANOL Property
- form
- Solid
- color
- White to off-white
- InChI
- InChI=1S/C20H26O5/c1-9(2)10-8-11-12(15(23)13(10)21)20-7-5-6-19(3,4)17(20)16(14(11)22)25-18(20)24/h8-9,14,16-17,21-23H,5-7H2,1-4H3/t14-,16-,17+,20+/m1/s1
- InChIKey
- LCAZOMIGFDQMNC-PYQAKABTSA-N
- SMILES
- C1(C)(C)[C@@]2([H])[C@]3(C(=O)O[C@]2([H])[C@H](O)C2=C3C(O)=C(O)C(C(C)C)=C2)CCC1
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EPIROSMANOL Chemical Properties,Usage,Production
Uses
Epirosmanol is a nature diterpene lactone from S. officinalis. Epirosmanol shows anti-cancer activity and inhibits melanin biosynthesis against melanoma cells. Epirosmanol also exhibits DPPH radical scavenging activity[1][2].
Definition
ChEBI: Epirosmanol is a diterpene lactone.
References
[1] Sallam A, et al. Acetylcholine esterase inhibitors and melanin synthesis inhibitors from Salvia officinalis. Phytomedicine. 2016 Sep 15. 23(10):1005-11. DOI:10.1016/j.phymed.2016.06.014
[2] Miura K, et al. Antioxidant activity of chemical components from sage (Salvia officinalis L.) and thyme (Thymus vulgaris L.) measured by the oil stability index method. J Agric Food Chem. 2002 Mar 27;50(7):1845-51. DOI:10.1021/jf011314o
EPIROSMANOL Preparation Products And Raw materials
Raw materials
Preparation Products
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