5-chloro-2-methoxy-phenol
- Product Name
- 5-chloro-2-methoxy-phenol
- CAS No.
- 3743-23-5
- Chemical Name
- 5-chloro-2-methoxy-phenol
- Synonyms
- 5-Chloroguaiacol;5-chloro-2-methoxyphenole;5-chloro-2-methoxy-phenol;2-Hydroxy-4-chloroanisole;Phenol, 5-chloro-2-methoxy-;4-Chloro-2-hydroxyanisole, 4-Chloro-2-hydroxyphenyl methyl ether
- CBNumber
- CB61457951
- Molecular Formula
- C7H7ClO2
- Formula Weight
- 158.58
- MOL File
- 3743-23-5.mol
5-chloro-2-methoxy-phenol Property
- Melting point:
- 161-163.5℃
- Boiling point:
- 237-239℃ (760 Torr)
- Density
- 1.280±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- form
- crystalline powder
- pka
- 9.01±0.10(Predicted)
- color
- Creamy to faint tan
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- OR60133
- Product name
- 5-Chloro-2-methoxyphenol
- Packaging
- 250mg
- Price
- $56
- Updated
- 2021/12/16
- Product number
- 2607-5-X3
- Product name
- 5-Chloro-2-methoxyphenol
- Packaging
- 250mg
- Price
- $61
- Updated
- 2021/12/16
- Product number
- OR60133
- Product name
- 5-Chloro-2-methoxyphenol
- Packaging
- 1g
- Price
- $135
- Updated
- 2021/12/16
- Product number
- 2607-5-X3
- Product name
- 5-Chloro-2-methoxyphenol
- Packaging
- 1g
- Price
- $149
- Updated
- 2021/12/16
- Product number
- 4776AB
- Product name
- 5-Chloro-2-methoxyphenol
- Packaging
- 1g
- Price
- $158
- Updated
- 2021/12/16
5-chloro-2-methoxy-phenol Chemical Properties,Usage,Production
Synthesis
89694-48-4
3743-23-5
General procedure for the synthesis of 5-chloro-2-methoxyphenylboronic acid as a raw material for the synthesis of 5-chloro-2-methoxyphenol: 5-chloro-2-methoxyphenylboronic acid (5.0 g, 26.82 mmol) was dissolved in water (20 mL) at room temperature, followed by the addition of sodium hydroxide pellets (1.6 g, 40.23 mmol). The reaction mixture was stirred for 20 min and then sodium bicarbonate solution (20 mL) was added, followed by acetone (50 mL) and EDTA (0.8 g, 2.68 mmol). The mixture was cooled to 0°C and Oxone? (18.0 g, 29.51 mmol) was added. The mixture was slowly warmed to room temperature over 24 h. Sodium sulfite (1.20 g) was subsequently added, followed by concentrated hydrochloric acid (15 mL) and EtOAc (30 mL). The organic and aqueous phases were separated and the aqueous phase was re-extracted with EtOAc (30 mL). The organic phases were combined, dried with magnesium sulfate, and concentrated under reduced pressure to remove the solvent to afford the target product 5-chloro-2-methoxyphenol in a yield of 4.0 g (95% yield). The product was characterized by 1H NMR (400 MHz, CDCl3): δ 3.90 (3H, s), 5.60 (1H, s), 6.80 (1H, d), 6.90 (1H, d), 6.95 (1H, s).
References
[1] Patent: WO2006/67587, 2006, A2. Location in patent: Page/Page column 22; 23
[2] Patent: US6207662, 2001, B1
5-chloro-2-methoxy-phenol Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 5-chloro-2-methoxy-phenol manufacturers
- Product
- 2-Hydroxy-4-chloroanisole 3743-23-5
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20t
- Release date
- 2024-07-14
- Product
- 5-chloro-2-methoxy-phenol 3743-23-5
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-10
- Product
- 5-chloro-2-methoxy-phenol 3743-23-5
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-09