N-Bromoacetyl--alanine

Product Name: N-Bromoacetyl--alanine
CAS No.: 89520-11-6
Chemical Name: N-Bromoacetyl--alanine
Synonyms: N-Bromoacetyl--alanine;N-Bromoacetyl-2-alanine;N-Bromoacetyl-β-alanine;N-Bromoacetyl-Beta-Alanine;β-Alanine, N-(2-bromoacetyl)-;(S)-2-(2-bromoacetamido)propanoic acid
CBNumber: CB61873364
Molecular Formula: C5H8BrNO3
Formula Weight: 210.03
MOL File: 89520-11-6.mol

More

Less

N-Bromoacetyl--alanine Property

Melting point:: 71-77°C
Boiling point:: 433.4±30.0 °C(Predicted)
Density: 1.682±0.06 g/cm3(Predicted)
solubility: Dichloromethane
form: Pale Yellow Semi-Solid
pka: 4.27±0.10(Predicted)

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

N-Bromosuccinimide Price

TRC

Product number: B679080
Product name: N-Bromoacetyl-β-alanine
Packaging: 2.5g
Price: $1230
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: AAA0004880
Product name: N-BROMOACETYL-BETA-ALANINE
Purity: 95.00%
Packaging: 250MG
Price: $1420.65
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: AAA0004880
Product name: N-BROMOACETYL-BETA-ALANINE
Purity: 95.00%
Packaging: 2.5G
Price: $1947
Updated: 2021/12/16

BroadPharm

Product number: BP-21092
Product name: 3-(2-bromoacetamido)propanoicacid
Purity: 97%
Packaging: 1g
Price: $850
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4158-9-04
Product name: 3-(2-Bromoacetamido)propanoic acid
Packaging: 250mg
Price: $877
Updated: 2021/12/16

More

Less

N-Bromoacetyl--alanine Chemical Properties,Usage,Production

Description

3-(2-bromoacetamido)propanoic acid is a compound containing a bromide group and a terminal carboxylic acid. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Chemical Properties

Pale Yellow Semi-Solid

Uses

N-Bromoacetyl-β-alanine is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. N-Bromoacetyl-β-alanine is also a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[2].

IC 50

Alkyl-Chain; Cleavable Linker

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. DOI:10.1016/j.ebiom.2018.09.005
[2] Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337. DOI:10.1038/nrd.2016.268

N-Bromoacetyl--alanine Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

N-Bromoacetyl--alanine Suppliers

Canada 1 China 29 India 1 United Kingdom 1 United States 4 Global 36

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32321
Advantage: 50

Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 18892239720
Fax: 010-60605840
Email: psaitong@jm-bio.com
Country: China
ProdList: 12306
Advantage: 58

Yantai ShengKailun Chemical Technology Co., Ltd.

Tel: 13356901049
Fax: QQ：1025383091
Email: 3119594100@qq.com
Country: China
ProdList: 7964
Advantage: 55

Shenzhen Polymeri Biochemical Technology Co., Ltd.

Tel: +86-400-002-6226 +86-13028896684;
Email: sales@rrkchem.com
Country: China
ProdList: 57422
Advantage: 58

Hangzhou Huarong Pharm Co., Ltd.

Tel: 571-86758373 +8613588754946
Fax: 0086-571-81131109
Email: sales@huarongpharm.com
Country: CHINA
ProdList: 3148
Advantage: 58

Jiangsu Hongmin Pharmaceutical Co., Ltd.

Tel: 18221292452
Email: fannieliu@glschina.com
Country: China
ProdList: 6798
Advantage: 58

Changzhou Kechem Bio-Scientific Co., LTD.

Tel: 0519-68985668 13685222090
Fax: qq735434464
Email: sales@kechem.cn
Country: China
ProdList: 26028
Advantage: 58

Energy Chemical

Tel: 021-58432009 400-005-6266
Fax: 021-58436166
Email: marketing@energy-chemical.com
Country: China
ProdList: 44918
Advantage: 58

Zhengzhou Akem Chemical Co., Ltd

Tel: 13303867194
Email: 3001317055@qq.com
Country: China
ProdList: 9682
Advantage: 58

Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 15801484223;
Email: psaitong@jm-bio.com
Country: China
ProdList: 29757
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-1647117 13681763483
Email: product02@bidepharm.com
Country: China
ProdList: 62220
Advantage: 58

Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd

Tel: 0431-80514535 19917294565
Email: et@chemextension.com
Country: China
ProdList: 5061
Advantage: 58

Henan Alpha Chemical Co., Ltd.

Tel: 0371-55013243 15324716602
Email: 2853979810@qq.com
Country: China
ProdList: 9898
Advantage: 58

Aobolihui

Tel: 0917-18691729 18691729963
Email: 2553382659@qq.com
Country: China
ProdList: 4739
Advantage: 58

Yantai Sheng Kai Lun Biological Products Co. , Ltd.

Tel: 13356901049
Email: mark@sklnchem.cn
Country: China
ProdList: 8000
Advantage: 58

Shanghai Haohong Scientific Co., Ltd.

Tel: 400-8210725 4008210725
Email: malulu@leyan.com
Country: China
ProdList: 39845
Advantage: 58

Accela ChemBio Co.,Ltd.

Tel: 021-50795510 4000665055
Email: SY06@accelachem.com
Country: China
ProdList: 7514
Advantage: 58

Honghanyanxin Pharm

Tel: 0551-62626652 19334025048
Email: sales-honghanyanxin@aliyun.com
Country: China
ProdList: 1164
Advantage: 58

Hefei Mokai Pharmaceutical Technology Co., Ltd

Tel: 19355912709
Email: 690231469@qq.com
Country: China
ProdList: 7593
Advantage: 58

Jilin Chinese Academy of Sciences-yanshen Technology

Tel: 18143011203
Email: ET-market@chemextension.com
Country: China
ProdList: 31997
Advantage: 58

RD International Technology Co., Limited

Tel: 18024082417
Email: market@ubiochem.com
Country: China
ProdList: 9835
Advantage: 58

TargetMol Chemicals Inc.

Tel: 15002134094
Email: marketing@targetmol.cn
Country: China
ProdList: 29573
Advantage: 58

Hubei Danding Pharmaceutical Technology Co., Ltd

Tel: 17701422019
Email: 1559451077@qq.com
Country: China
ProdList: 8171
Advantage: 58

Aikon International Limited

Tel: 025-58851090 13408877820
Email: 2850281427@qq.com
Country: China
ProdList: 10000
Advantage: 58

Sichuan jiayinglai technology CO.,LTD

Tel: 028-64159575
Email: 1678230860@qq.com
Country: China
ProdList: 6511
Advantage: 58

Santa Cruz Biotechnology Inc

Tel: 021-60936350
Email: scbt@scbt.com
Country: China
ProdList: 6594
Advantage: 58

Jilin Chinese Academy of Sciences-yanshen Technology

Tel: +undefined18143011203
Email: info@chemextension.com
Country: China
ProdList: 42056
Advantage: 58

Absin Bioscience Inc.

Tel: --
Fax: --
Email: chenjw@absin.cn
Country: CHINA
ProdList: 6208
Advantage: 58

89520-11-6, N-Bromoacetyl--alanineRelated Search:

N-Bromoacetyl--alanine

N-Bromoacetyl-2-alanine

N-Bromoacetyl-Beta-Alanine

β-Alanine, N-(2-bromoacetyl)-

N-Bromoacetyl-β-alanine

(S)-2-(2-bromoacetamido)propanoic acid

89520-11-6

MTS & Sulfhydryl Active Reagents

Amino Acids & Derivatives