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GGSTOPTM

Product Name
GGSTOPTM
CAS No.
926281-37-0
Chemical Name
GGSTOPTM
Synonyms
GGsTop;GGSTOPTM;GGsTop(R);GGsTop (Nahlsgen);GGsTop (Synonyms: Nahlsgen);3-[[(3-Amino-3-carboxypropyl)methoxyphosphinyl]oxy]benzeneacetic acid;2-Amino-4-((3-(carboxymethyl)phenoxy)(methoxy)phosphoryl)butanoic acid;Benzeneacetic acid, 3-[[(3-amino-3-carboxypropyl)methoxyphosphinyl]oxy]-
CBNumber
CB62467186
Molecular Formula
C13H18NO7P
Formula Weight
331.26
MOL File
926281-37-0.mol
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GGSTOPTM Property

Boiling point:
557.7±50.0 °C(Predicted)
Density 
1.403±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
<33.13mg/ml in H2O; <33.13mg/ml in DMSO
form 
solid
pka
2.18±0.10(Predicted)
color 
White
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris
Product number
4452
Product name
GGsTop
Purity
≥95%(HPLC)
Packaging
10
Price
$235
Updated
2021/12/16
TRC
Product number
N497063
Product name
Nahlsgen
Packaging
10mg
Price
$160
Updated
2021/12/16
Usbiological
Product number
255372
Product name
GGsTop
Packaging
10mg
Price
$522
Updated
2021/12/16
ApexBio Technology
Product number
B5602
Product name
GGsTop
Packaging
10mg
Price
$345
Updated
2021/12/16
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GGSTOPTM Chemical Properties,Usage,Production

Uses

Nahlsgen is a highly selective, and irreversible γ-?glutamyl transpeptidase (GGT) inhibitor with no inhibitory activity on glutamine amidotransferases.

in vivo

GGsTop (1 mg/kg) lowers levels of ALT, AST, γ-GT at 12, 24, and 48 h after ischemia-reperfusion in rats[3].
GGsTop also reduces 4-HNE and TNF-α production, and decreases hepatic necrosis in rats[3].

Animal Model:Male rats (9 week old)[3]
Dosage:1 mg/kg
Administration:Injected into the inferior vena cava for 12, 24, 48 h
Result:Lowered the serum levels of ALT, AST, prevented the increase of serum γ-GT levels in IR-GGsTop group.

storage

Store at -20°C

GGSTOPTM Preparation Products And Raw materials

Raw materials

Preparation Products

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GGSTOPTM Suppliers

Shenzhen Fulkare Biotechnology Co., Ltd.
Tel
15953196022
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fulkare@163.com
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China
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Nanjing Chemlin Chemical Co., Ltd
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025-83697070
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+86-25-83453306
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Shanghai Aladdin Bio-Chem Technology Co.,LTD
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400-6206333 13167063860
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Nanjing Dulai Biotechnology Co., Ltd.
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025-846993838003-8003 18013301590
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MedBioPharmaceutical Technology Inc
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TargetMol Chemicals Inc.
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926281-37-0, GGSTOPTMRelated Search:


  • GGSTOPTM
  • 3-[[(3-Amino-3-carboxypropyl)methoxyphosphinyl]oxy]benzeneacetic acid
  • GGsTop
  • GGsTop (Nahlsgen)
  • GGsTop (Synonyms: Nahlsgen)
  • Benzeneacetic acid, 3-[[(3-amino-3-carboxypropyl)methoxyphosphinyl]oxy]-
  • 2-Amino-4-((3-(carboxymethyl)phenoxy)(methoxy)phosphoryl)butanoic acid
  • GGsTop(R)
  • 926281-37-0