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VEGFR2 Kinase Inhibitor II

Product Name
VEGFR2 Kinase Inhibitor II
CAS No.
288144-20-7
Chemical Name
VEGFR2 Kinase Inhibitor II
Synonyms
VEGFR2 Kinase Inhibitor II;VEGFR2 Kinase Inhibitor II,VEGFR-2 Kinase Inhibitor II;VEGFR2 Kinase Inhibitor II - CAS 288144-20-7 - Calbiochem;(3Z)-5-bromo-3-(4,5,6,7-tetrahydro-1H-indol-2-ylmethylidene)-1H-indol-2-one;2H-Indol-2-one, 5-bromo-1,3-dihydro-3-[(4,5,6,7-tetrahydro-1H-indol-2-yl)methylene]-, (3Z)-
CBNumber
CB62501837
Molecular Formula
C17H15BrN2O
Formula Weight
343.22
MOL File
288144-20-7.mol
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VEGFR2 Kinase Inhibitor II Property

storage temp. 
-20C
solubility 
DMF: 20 mg/ml; DMSO: 10 mg/ml
form 
Brown solid
color 
brown
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
17544
Product name
VEGFR2 Kinase Inhibitor II
Purity
≥95%
Packaging
500μg
Price
$85
Updated
2024/03/01
Cayman Chemical
Product number
17544
Product name
VEGFR2 Kinase Inhibitor II
Purity
≥95%
Packaging
1mg
Price
$158
Updated
2024/03/01
Cayman Chemical
Product number
17544
Product name
VEGFR2 Kinase Inhibitor II
Purity
≥95%
Packaging
5mg
Price
$661
Updated
2024/03/01
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VEGFR2 Kinase Inhibitor II Chemical Properties,Usage,Production

General Description

A cell-permeable and reversible indolin-2-one class of receptor tyrosine kinase (RTK) inhibitor [IC50 = 70 nM for VEGF-R2 (KDR/Flk-1), 920 nM for PDGF-Rβ, 4.92 μM for p60c-src, and 13.3 μM for FGF-R1]. The inhibition is suggested to be competitive with respective to ATP. Also inhibits VEGF-induced (IC50 = 110 nM) and PDGF-induced (IC50 = 2.01 μM) cell proliferation in umbilical vein endothelial cells (HUVEC). Does not exhibit any inhibitory effect on EGF-R kinase activity (IC50 >100 μM).

Biochem/physiol Actions

Cell permeable: yes

VEGFR2 Kinase Inhibitor II Preparation Products And Raw materials

Raw materials

Preparation Products

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VEGFR2 Kinase Inhibitor II Suppliers

VDM Biochemicals
Tel
0330-2528181
Fax
0330-2528171
Email
sales@vdmbio.com
Country
United States
ProdList
510
Advantage
64
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51456
Advantage
80
BOC Sciences
Tel
16314854226
Email
info@bocsci.com
Country
United States
ProdList
9923
Advantage
65
Shanghai Hongye Biotechnology Co. Ltd
Tel
400-9205774
Email
sales@glpbio.cn
Country
China
ProdList
6777
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32161
Advantage
58
Jinan ponder chemical co. LTD
Tel
0531-0000
Email
thinklifescience@163.com
Country
China
ProdList
19689
Advantage
58
MedBioPharmaceutical Technology Inc
Tel
021-69568360 18916172912
Email
order@med-bio.cn
Country
China
ProdList
8140
Advantage
58
TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
ProdList
24644
Advantage
58
Shanghai Yifei Biotechnology Co. , Ltd.
Tel
021-65675885 18964387627
Email
customer_service@efebio.com
Country
China
ProdList
11974
Advantage
58
Hangzhou MolCore BioPharmatech Co.,Ltd.
Tel
+86-057181025280; +8617767106207
Fax
0571-85806285
Email
sales@molcore.com
Country
China
ProdList
49734
Advantage
58

288144-20-7, VEGFR2 Kinase Inhibitor IIRelated Search:


  • VEGFR2 Kinase Inhibitor II
  • (3Z)-5-bromo-3-(4,5,6,7-tetrahydro-1H-indol-2-ylmethylidene)-1H-indol-2-one
  • VEGFR2 Kinase Inhibitor II - CAS 288144-20-7 - Calbiochem
  • 2H-Indol-2-one, 5-bromo-1,3-dihydro-3-[(4,5,6,7-tetrahydro-1H-indol-2-yl)methylene]-, (3Z)-
  • VEGFR2 Kinase Inhibitor II,VEGFR-2 Kinase Inhibitor II
  • 288144-20-7
  • Angiogenesis and Metastasis