ChemicalBook > CAS DataBase List > VEGFR2 Kinase Inhibitor II
VEGFR2 Kinase Inhibitor II
- Product Name
- VEGFR2 Kinase Inhibitor II
- CAS No.
- 288144-20-7
- Chemical Name
- VEGFR2 Kinase Inhibitor II
- Synonyms
- VEGFR2 Kinase Inhibitor II;VEGFR2 Kinase Inhibitor II,VEGFR-2 Kinase Inhibitor II;VEGFR2 Kinase Inhibitor II - CAS 288144-20-7 - Calbiochem;(3Z)-5-bromo-3-(4,5,6,7-tetrahydro-1H-indol-2-ylmethylidene)-1H-indol-2-one;2H-Indol-2-one, 5-bromo-1,3-dihydro-3-[(4,5,6,7-tetrahydro-1H-indol-2-yl)methylene]-, (3Z)-
- CBNumber
- CB62501837
- Molecular Formula
- C17H15BrN2O
- Formula Weight
- 343.22
- MOL File
- 288144-20-7.mol
More
Less
VEGFR2 Kinase Inhibitor II Property
- storage temp.
- -20C
- solubility
- DMF: 20 mg/ml; DMSO: 10 mg/ml
- form
- Brown solid
- color
- brown
More
Less
N-Bromosuccinimide Price
Cayman Chemical
- Product number
- 17544
- Product name
- VEGFR2 Kinase Inhibitor II
- Purity
- ≥95%
- Packaging
- 500μg
- Price
- $85
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 17544
- Product name
- VEGFR2 Kinase Inhibitor II
- Purity
- ≥95%
- Packaging
- 1mg
- Price
- $158
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 17544
- Product name
- VEGFR2 Kinase Inhibitor II
- Purity
- ≥95%
- Packaging
- 5mg
- Price
- $661
- Updated
- 2024/03/01
More
Less
VEGFR2 Kinase Inhibitor II Chemical Properties,Usage,Production
General Description
A cell-permeable and reversible indolin-2-one class of receptor tyrosine kinase (RTK) inhibitor [IC50 = 70 nM for VEGF-R2 (KDR/Flk-1), 920 nM for PDGF-Rβ, 4.92 μM for p60c-src, and 13.3 μM for FGF-R1]. The inhibition is suggested to be competitive with respective to ATP. Also inhibits VEGF-induced (IC50 = 110 nM) and PDGF-induced (IC50 = 2.01 μM) cell proliferation in umbilical vein endothelial cells (HUVEC). Does not exhibit any inhibitory effect on EGF-R kinase activity (IC50 >100 μM).
Biochem/physiol Actions
Cell permeable: yes
VEGFR2 Kinase Inhibitor II Preparation Products And Raw materials
Raw materials
Preparation Products
More
Less
VEGFR2 Kinase Inhibitor II Suppliers
- Tel
- 0330-2528181
- Fax
- 0330-2528171
- sales@vdmbio.com
- Country
- United States
- ProdList
- 510
- Advantage
- 64
- Tel
- 021-61415566 800-8193336
- orderCN@merckgroup.com
- Country
- China
- ProdList
- 51456
- Advantage
- 80
- Tel
- 16314854226
- info@bocsci.com
- Country
- United States
- ProdList
- 9923
- Advantage
- 65
- Tel
- 400-9205774
- sales@glpbio.cn
- Country
- China
- ProdList
- 6777
- Advantage
- 58
- Tel
- +1-781-999-5354 +1-00000000000
- marketing@targetmol.com
- Country
- United States
- ProdList
- 32161
- Advantage
- 58
- Tel
- 0531-0000
- thinklifescience@163.com
- Country
- China
- ProdList
- 19689
- Advantage
- 58
- Tel
- 021-69568360 18916172912
- order@med-bio.cn
- Country
- China
- ProdList
- 8140
- Advantage
- 58
- Tel
- 4008200310
- marketing@tsbiochem.com
- Country
- China
- ProdList
- 24644
- Advantage
- 58
- Tel
- 021-65675885 18964387627
- customer_service@efebio.com
- Country
- China
- ProdList
- 11974
- Advantage
- 58
- Tel
- +86-057181025280; +8617767106207
- Fax
- 0571-85806285
- sales@molcore.com
- Country
- China
- ProdList
- 49734
- Advantage
- 58