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VEGFR2 Kinase Inhibitor II

Product Name
VEGFR2 Kinase Inhibitor II
CAS No.
288144-20-7
Chemical Name
VEGFR2 Kinase Inhibitor II
Synonyms
VEGFR2 Kinase Inhibitor II;VEGFR2 Kinase Inhibitor II,VEGFR-2 Kinase Inhibitor II;VEGFR2 Kinase Inhibitor II - CAS 288144-20-7 - Calbiochem;(3Z)-5-bromo-3-(4,5,6,7-tetrahydro-1H-indol-2-ylmethylidene)-1H-indol-2-one;2H-Indol-2-one, 5-bromo-1,3-dihydro-3-[(4,5,6,7-tetrahydro-1H-indol-2-yl)methylene]-, (3Z)-
CBNumber
CB62501837
Molecular Formula
C17H15BrN2O
Formula Weight
343.22
MOL File
288144-20-7.mol
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VEGFR2 Kinase Inhibitor II Property

storage temp. 
-20C
solubility 
DMF: 20 mg/ml; DMSO: 10 mg/ml
form 
Brown solid
color 
brown
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
17544
Product name
VEGFR2 Kinase Inhibitor II
Purity
≥95%
Packaging
500μg
Price
$85
Updated
2024/03/01
Cayman Chemical
Product number
17544
Product name
VEGFR2 Kinase Inhibitor II
Purity
≥95%
Packaging
1mg
Price
$158
Updated
2024/03/01
Cayman Chemical
Product number
17544
Product name
VEGFR2 Kinase Inhibitor II
Purity
≥95%
Packaging
5mg
Price
$661
Updated
2024/03/01
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VEGFR2 Kinase Inhibitor II Chemical Properties,Usage,Production

General Description

A cell-permeable and reversible indolin-2-one class of receptor tyrosine kinase (RTK) inhibitor [IC50 = 70 nM for VEGF-R2 (KDR/Flk-1), 920 nM for PDGF-Rβ, 4.92 μM for p60c-src, and 13.3 μM for FGF-R1]. The inhibition is suggested to be competitive with respective to ATP. Also inhibits VEGF-induced (IC50 = 110 nM) and PDGF-induced (IC50 = 2.01 μM) cell proliferation in umbilical vein endothelial cells (HUVEC). Does not exhibit any inhibitory effect on EGF-R kinase activity (IC50 >100 μM).

Biochem/physiol Actions

Cell permeable: yes

VEGFR2 Kinase Inhibitor II Preparation Products And Raw materials

Raw materials

Preparation Products

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VEGFR2 Kinase Inhibitor II Suppliers

China 10 United States 5 Global 15
VDM Biochemicals
Tel
0330-2528181
Fax
0330-2528171
Email
sales@vdmbio.com
Country
United States
ProdList
510
Advantage
64
BOC Sciences
Tel
16314854226
Email
info@bocsci.com
Country
United States
ProdList
9923
Advantage
65
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32161
Advantage
58
Cayman Chemical Company
Tel
--
Fax
--
Email
cayman@caymanchem.com
Country
United States
ProdList
6213
Advantage
81
Riedel-de Haen AG
Tel
--
Fax
--
Country
United States
ProdList
6773
Advantage
87

288144-20-7, VEGFR2 Kinase Inhibitor IIRelated Search:


  • VEGFR2 Kinase Inhibitor II
  • (3Z)-5-bromo-3-(4,5,6,7-tetrahydro-1H-indol-2-ylmethylidene)-1H-indol-2-one
  • VEGFR2 Kinase Inhibitor II - CAS 288144-20-7 - Calbiochem
  • 2H-Indol-2-one, 5-bromo-1,3-dihydro-3-[(4,5,6,7-tetrahydro-1H-indol-2-yl)methylene]-, (3Z)-
  • VEGFR2 Kinase Inhibitor II,VEGFR-2 Kinase Inhibitor II
  • 288144-20-7
  • Angiogenesis and Metastasis