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M 1145

Product Name
M 1145
CAS No.
1172089-00-7
Chemical Name
M 1145
Synonyms
M 1145;L-Alaninamide, L-arginylglycyl-L-arginylglycyl-L-asparaginyl-L-tryptophyl-L-threonyl-L-leucyl-L-asparaginyl-L-seryl-L-alanylglycyl-L-tyrosyl-L-leucyl-L-leucylglycyl-L-prolyl-L-valyl-L-leucyl-L-prolyl-L-prolyl-L-prolyl-L-alanyl-L-leucyl-L-alanyl-L-leucyl-
CBNumber
CB62518703
Molecular Formula
C128H205N37O32
Formula Weight
2774.23
MOL File
1172089-00-7.mol
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M 1145 Property

Density 
1.45±0.1 g/cm3(Predicted)
storage temp. 
Desiccate at -20°C
form 
Powder
color 
White to off-white
Water Solubility 
Soluble to 5 mg/ml in water
Sequence
Arg-Gly-Arg-Gly-Asn-Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-Gly-Pro-Val-Leu-Pro-Pro-Pro-Ala-Leu-Ala-Leu-Ala-NH2
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris
Product number
3629
Product name
M1145
Packaging
500U
Price
$346
Updated
2021/12/16
Usbiological
Product number
255739
Product name
M 1145
Packaging
500ug
Price
$616
Updated
2021/12/16
ApexBio Technology
Product number
B5464
Product name
M1145
Packaging
500ug
Price
$511
Updated
2021/12/16
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M 1145 Chemical Properties,Usage,Production

Uses

M1145, a chimeric peptide, is a selective galanin receptor type 2 (GAL2) agonist, with a Ki of 6.55 nM. M1145 shows more than 90-fold higher affinity for GAL2 over GAL1 (Ki=587 nM) and a 76-fold higher affinity over GalR3 (Ki=497 nM). M1145 has an additive effect on the signal transduction of galanin[1].

References

[1] Runesson J, Saar I, Lundstr?m L, J?rv J, Langel U. A novel GalR2-specific peptide agonist. Neuropeptides. 2009;43(3):187-192. DOI:10.1016/j.npep.2009.04.004

M 1145 Preparation Products And Raw materials

Raw materials

Preparation Products

1172089-00-7, M 1145Related Search:


  • M 1145
  • L-Alaninamide, L-arginylglycyl-L-arginylglycyl-L-asparaginyl-L-tryptophyl-L-threonyl-L-leucyl-L-asparaginyl-L-seryl-L-alanylglycyl-L-tyrosyl-L-leucyl-L-leucylglycyl-L-prolyl-L-valyl-L-leucyl-L-prolyl-L-prolyl-L-prolyl-L-alanyl-L-leucyl-L-alanyl-L-leucyl-
  • 1172089-00-7
  • C128H205N37O32