ChemicalBook > CAS DataBase List > (R)-N-FMoc-2-(2'-propynyl)alanine

(R)-N-FMoc-2-(2'-propynyl)alanine

Product Name
(R)-N-FMoc-2-(2'-propynyl)alanine
CAS No.
1198791-65-9
Chemical Name
(R)-N-FMoc-2-(2'-propynyl)alanine
Synonyms
R3(YNE);Fmoc-alpha-Prg-L-Ala-OH;Fmoc-(R)-propargyl-Ala-OH;FMoc-α-Me-D-Gly(Propargyl)-OH;(R)-N-FMOC-Α-PROPARGYLALANINE;(R)-N-Fmoc-a-Propargylalanine;Fmoc-α-Me-D-Gly(Propargyl)-OH;Fmoc-(R)-propargyl-Ala-OH;(R)-N-FMoc-2-(2'-propynyl)alanine;(R)-N-Fmoc-2-(2'-propynyl)alanine, >97%
CBNumber
CB62645674
Molecular Formula
C21H19NO4
Formula Weight
349.38
MOL File
1198791-65-9.mol
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(R)-N-FMoc-2-(2'-propynyl)alanine Property

Boiling point:
576.8±50.0 °C(Predicted)
Density 
1.267±0.06 g/cm3(Predicted)
storage temp. 
-20°C
pka
3.51±0.11(Predicted)
form 
liquid
color 
pale yellow
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Safety

Hazard Codes 
Xn
Risk Statements 
36-42/43
Safety Statements 
22-26-36/37-45
TSCA 
No
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H400Very toxic to aquatic life

Precautionary statements

P273Avoid release to the environment.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
F5312
Product name
Fmoc-(R)-propargyl-Ala-OH
Packaging
1G
Price
$644
Updated
2025/07/31
Sigma-Aldrich
Product number
F5312
Product name
Fmoc-(R)-propargyl-Ala-OH
Packaging
250MG
Price
$324
Updated
2023/06/20
TRC
Product number
F679790
Product name
Fmoc-​(R)​-​propargyl-​Ala-​OH
Packaging
50mg
Price
$140
Updated
2021/12/16
ChemSupplyAustralia
Product number
300567
Product name
(R)-N-Fmoc-α-Propargylalanine, 98%
Packaging
100mg
Price
$90.2
Updated
2021/12/16
Activate Scientific
Product number
AS115975
Product name
(R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-methylpent-4-ynoic acid
Purity
97+% ee
Packaging
1g
Price
$502
Updated
2021/12/16
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(R)-N-FMoc-2-(2'-propynyl)alanine Chemical Properties,Usage,Production

Uses

Fmoc-?(R)?-?propargyl-?Ala-?OH is a chiral reagent used in the preparation of peptidomimetic macrocycles for the transport of biomolecules.

Uses

Alkyne amino acid, more stable for peptide stapling via click chemistry than propargylglycine.

reaction suitability

reaction type: click chemistry

(R)-N-FMoc-2-(2'-propynyl)alanine Preparation Products And Raw materials

Raw materials

Preparation Products

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(R)-N-FMoc-2-(2'-propynyl)alanine Suppliers

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1198791-65-9, (R)-N-FMoc-2-(2'-propynyl)alanineRelated Search:

α-Me-Gly(Propargyl)-OH N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-isovaline (S)-2-(((9H-fluoren-9-yl)Methoxy)carbonylaMino)-6-azido-2-Methylhexanoic acid FMoc-α-Me-Gly(Pentynyl)-OH FMoc-(R)-2-aMino-2-Methylbutanoic acid (R)- 2-(3'-butenyl) alanine (R)-N-Fmoc-2-(3'-butenyl)alanine (R)-N-BOC-alpha-Ethylalanine, 98% ee, 98% (R)-N-FMoc-2-(5'-pentenyl)alanine (R)-N-FMoc-2-(6'-heptenyl)alanine (S)-2-amino-2-methyl-4-pentenoicacid FMoc-α-Me-Gly(6-azidohexanyl)-OH (S)-N-FMoc-2-(2'--propynyl)alanine (S)-N-Fmoc-2-(3'-butenyl)alanine (S)-N-FMoc-2-(5'-pentenyl)alanine (S)-N-FMoc-2-(6'-heptenyl)alanine (S)-N-BOC-alpha-Ethylalanine, 98% ee, 98% (R)-2-amino-2-methyl-hept-6-enoic acid

  • (R)-N-FMoc-2-(2'-propynyl)alanine
  • (R)-2-((((9H-Fluoren-9-yl)Methoxy)carbonyl)aMino)-2-Methylpent-4-ynoic acid
  • (R)-N-FMOC-Α-PROPARGYLALANINE
  • FMoc-α-Me-D-Gly(Propargyl)-OH
  • (9H-Fluoren-9-yl)MethOxy]Carbonyl Alpha-Methyl-D-Gly(Propargyl)-OH
  • Fmoc-alpha-Prg-L-Ala-OH
  • (R)-N-Fmoc-2-(2'-propynyl)alanine, >97%
  • (2R)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2-methylpent-4-ynoic acid
  • Fmoc-(R)-2-amino-2-methylpent-4-ynoic acid
  • 4-Pentynoic acid, 2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-2-methyl-, (2R)-
  • Fmoc-(R)-propargyl-Ala-OH
  • N-α-(9-Fluorenylmethoxycarbonyl)-α-methyl-D-α-propargylglycine
  • R3(YNE)
  • Fmoc-(R)-2-amino-2-methyl-4-pentynoic acid
  • (R)-2-(Fmoc-amino)-2-methyl-4-pentynoic Acid
  • (R)-N-Fmoc-a-Propargylalanine
  • Fmoc-α-Me-D-Gly(Propargyl)-OH
  • Fmoc-(<i>R</i>)-propargyl-Ala-OH
  • 1198791-65-9
  • α-Methyl Amino Acids