Terpendole E
- Product Name
- Terpendole E
- CAS No.
- 167427-23-8
- Chemical Name
- Terpendole E
- Synonyms
- FO 2546L;Terpendole E;Terpendole E >=95% (HPLC);1-Benzopyrano[5',6':6,7]indeno[1,2-b]isobenzofuro[5,6-e]indole-2-methanol, 3,4,4a,4b,5,6,6a,7,12,12b,12c,13,14,14a-tetradecahydro-4-hydroxy-α,α,4a,12b,12c-pentamethyl-, (2S,4R,4aR,4bR,6aS,12bS,12cS,14aS)-
- CBNumber
- CB62650814
- Molecular Formula
- C28H39NO3
- Formula Weight
- 437.61
- MOL File
- 167427-23-8.mol
Terpendole E Property
- Boiling point:
- 597.1±50.0 °C(Predicted)
- Density
- 1.194±0.06 g/cm3(Predicted)
- storage temp.
- -20°C
- solubility
- DMSO: 10mg/mL, clear
- form
- powder
- pka
- 14.45±0.70(Predicted)
- color
- white to beige
- biological source
- Albophoma yamanashiensis
Safety
- WGK Germany
- 3
N-Bromosuccinimide Price
- Product number
- SML1127
- Product name
- Terpendole E
- Purity
- ≥95% (HPLC)
- Packaging
- 250μG
- Price
- $85.8
- Updated
- 2022/05/15
- Product number
- SML1127
- Product name
- Terpendole E
- Purity
- ≥95% (HPLC)
- Packaging
- 1MG
- Price
- $286
- Updated
- 2022/05/15
- Product number
- 045329
- Product name
- Terpendole E
- Packaging
- 250ug
- Price
- $312
- Updated
- 2021/12/16
- Product number
- T116620
- Product name
- TerpendoleE
- Packaging
- 1mg
- Price
- $1350
- Updated
- 2021/12/16
- Product number
- AG-CN2-0127-C250
- Product name
- TerpendoleE
- Purity
- ≥95%(HPLC)
- Packaging
- 250μg
- Price
- $75
- Updated
- 2021/12/16
Terpendole E Chemical Properties,Usage,Production
Uses
Acyl-coenzyme A:cholesterol acyltransferase (ACAT) isozymes are involved with cellular cholesterol esterification and regulate intestinal cholesterol absorption and hepatic lipoprotein secretion. Terpendole E is a related compound of Terpendole C (T116600), which is an inhibitor of ACAT1 and ACAT2 isozymes.
Definition
ChEBI: Terpendole E is an organic heterotricyclic compound and an organooxygen compound.
Biochem/physiol Actions
Terpendole E is a mitotic kinesin Eg5 (Kinesin-5) inhibitor isolated from Albophoma yamanashiensis that inhibits both motor and microtubule stimulated ATPase activities of human Eg5. Studies indicate that Terpendole E inhibits Eg5 mutants resistant to S-trityl-L-cysteine and other Eg5 inhibitors. Also, Terpendole E is an ACAT (Acyl-CoA:cholesterol acyltransferase) inhibitor.
IC 50
Eg5
Terpendole E Preparation Products And Raw materials
Raw materials
Preparation Products
Terpendole E Suppliers
- Tel
- 1-631-485-4226; 16314854226
- info@bocsci.com
- Country
- United States
- ProdList
- 12952
- Advantage
- 65
- Tel
- 021-51320588
- Fax
- 0086-21-51320502
- tauto@tautobiotech.com
- Country
- China
- ProdList
- 3988
- Advantage
- 66
- Tel
- 021-61415566 800-8193336
- orderCN@merckgroup.com
- Country
- China
- ProdList
- 51395
- Advantage
- 80
- Tel
- 021-65675885 18964387627
- Fax
- 021-65675885
- info@efebio.com
- Country
- China
- ProdList
- 9803
- Advantage
- 58
- Tel
- 021-58432009 400-005-6266
- Fax
- 021-58436166
- marketing1@energy-chemical.com
- Country
- China
- ProdList
- 44894
- Advantage
- 58
- Tel
- 4008200310
- marketing@tsbiochem.com
- Country
- China
- ProdList
- 24961
- Advantage
- 58
- Tel
- 41-6192660-40
- info@adipogen.com
- Country
- China
- ProdList
- 5293
- Advantage
- 58
- Tel
- 81356846296
- export@funakoshi.co.jp
- Country
- China
- ProdList
- 2347
- Advantage
- 58
- Tel
- 21-20338288
- ordercn@merckgroup.com
- Country
- China
- ProdList
- 6394
- Advantage
- 58
- Tel
- 021-60936350
- scbt@scbt.com
- Country
- China
- ProdList
- 6594
- Advantage
- 58