Bis-PEG6-NHS ester
- Product Name
- Bis-PEG6-NHS ester
- CAS No.
- 1526718-98-8
- Chemical Name
- Bis-PEG6-NHS ester
- Synonyms
- BIS-PEG6-NHS;Di-NHS Ester-PEG6;Bis(2,5-dioxopyrrolidin-1-yl) 4,7,10,13,16,19-hexaoxadocosanedioate;4,7,10,13,16,19-Hexaoxadocosanedioic acid, 1,22-bis(2,5-dioxo-1-pyrrolidinyl) ester
- CBNumber
- CB63062418
- Molecular Formula
- C24H36N2O14
- Formula Weight
- 576.55
- MOL File
- 1526718-98-8.mol
Bis-PEG6-NHS ester Property
- solubility
- Soluble in DMSO, DCM
- form
- Viscous Liquid
- color
- Colorless to light yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- CS-0107647
- Product name
- Bis-PEG6-NHSester
- Purity
- ≥97.0%
- Packaging
- 100mg
- Price
- $230
- Updated
- 2021/12/16
- Product number
- BP-21681
- Product name
- Bis-PEG6-NHSester
- Purity
- 98%
- Packaging
- 100mg
- Price
- $250
- Updated
- 2021/12/16
- Product number
- BP-21681
- Product name
- Bis-PEG6-NHSester
- Purity
- 98%
- Packaging
- 500mg
- Price
- $350
- Updated
- 2021/12/16
- Product number
- CS-0107647
- Product name
- Bis-PEG6-NHSester
- Purity
- ≥97.0%
- Packaging
- 250mg
- Price
- $400
- Updated
- 2021/12/16
- Product number
- BP-21681
- Product name
- Bis-PEG6-NHSester
- Purity
- 98%
- Packaging
- 1g
- Price
- $460
- Updated
- 2021/12/16
Bis-PEG6-NHS ester Chemical Properties,Usage,Production
Description
Bis-PEG6-NHS ester is a PEG linker containing two NHS ester groups. The hydrophilic PEG spacer increases solubility in aqueous media. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
Biological Activity
Bis-PEG6-NHS ester is a PROTAC bridge and belongs to the PEG class. It can be used to synthesize a range of PROTAC molecules. Also Bis-PEG6-NHS ester is a cleavable ADC linker for the synthesis of antibody drug conjugates (ADCs).
in vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
target
Cleavable
| PEGs
| Alkyl/ether
|
Bis-PEG6-NHS ester Preparation Products And Raw materials
Raw materials
Preparation Products
Bis-PEG6-NHS ester Suppliers
- Tel
- 021-61551611 13296011611
- Fax
- +86 21-50676805
- contact@trustwe.com
- Country
- China
- ProdList
- 9895
- Advantage
- 58
- Tel
- 400-8592883 15367835770
- Fax
- 0731-82251112
- viola@huatengsci.com
- Country
- China
- ProdList
- 5873
- Advantage
- 58
- Tel
- Fax
- -
- 13006575422@163.com
- Country
- China
- ProdList
- 6355
- Advantage
- 58
- Tel
- 0371-0371-55629727 13323845623
- Fax
- 037155629727
- 2885676761@qq.com
- Country
- China
- ProdList
- 10214
- Advantage
- 58
- Tel
- 010-60605840 18892239720
- Fax
- 010-60605840
- psaitong@jm-bio.com
- Country
- China
- ProdList
- 12306
- Advantage
- 58
- Tel
- 571-86101219 18768477782
- Fax
- -
- sales09@leobiochem.com
- Country
- China
- ProdList
- 433
- Advantage
- 58
- Tel
- +86-156-80926068 +86-15680926068
- 1924344760@qq.com
- Country
- China
- ProdList
- 4825
- Advantage
- 58
- Tel
- 0411-39042497
- Fax
- 0411-39042693
- sales@alphabiopharm.com
- Country
- China
- ProdList
- 1951
- Advantage
- 58
- Tel
- 025-66110311 13155353615
- qzhang@aikonchem.com
- Country
- China
- ProdList
- 15527
- Advantage
- 58
- Tel
- +86-0571-81612335 +8613336028439
- sales@nextpeptide.com
- Country
- China
- ProdList
- 19908
- Advantage
- 58
- Tel
- 571-86758373 +8613588754946
- Fax
- 0086-571-81131109
- sales@huarongpharm.com
- Country
- CHINA
- ProdList
- 3148
- Advantage
- 58
- Tel
- 0371-63284658 18135795563
- Fax
- QQ:2885349392
- 2885349392@qq.com
- Country
- China
- ProdList
- 9976
- Advantage
- 58
- Tel
- 029-86217788 13892832556
- 2440688701@qq.com
- Country
- China
- ProdList
- 2010
- Advantage
- 58
- Tel
- +86-023-6139-8061 +86-86-13650506873
- sales@chemdad.com
- Country
- China
- ProdList
- 39894
- Advantage
- 58
- Tel
- 021-58461859 15821823057
- service@aiviche.com
- Country
- China
- ProdList
- 49312
- Advantage
- 58
- Tel
- +86-021-61551413 +8618813727289
- contact@trustwe.com
- Country
- China
- ProdList
- 5738
- Advantage
- 58
- Tel
- 15817493340
- 981810490@qq.com
- Country
- China
- ProdList
- 1566
- Advantage
- 58
- Tel
- 021-58432009 400-005-6266
- Fax
- 021-58436166
- marketing@energy-chemical.com
- Country
- China
- ProdList
- 44918
- Advantage
- 58
- Tel
- 400-8210725 4008210725
- malulu@leyan.com
- Country
- China
- ProdList
- 39995
- Advantage
- 58
- Tel
- 400-1647117 13681763483
- product02@bidepharm.com
- Country
- China
- ProdList
- 62075
- Advantage
- 58
- Tel
- 0573-82087565 18966369783
- gemma_wang@ruiaobio.com
- Country
- China
- ProdList
- 647
- Advantage
- 58
- Tel
- 15841022315
- sales@affinitytech.cn
- Country
- China
- ProdList
- 3000
- Advantage
- 58
- Tel
- 0431-80514535 19917294565
- et@chemextension.com
- Country
- China
- ProdList
- 5061
- Advantage
- 58
- Tel
- 4008200310
- marketing@tsbiochem.com
- Country
- China
- ProdList
- 24644
- Advantage
- 58
- Tel
- 021-61734564
- August@easycdmo.com
- Country
- China
- ProdList
- 10030
- Advantage
- 58
- Tel
- 010-50973130 17801761073
- Gsiyu@solarbio.com
- Country
- China
- ProdList
- 50464
- Advantage
- 58
- Tel
- 13271120151
- 1124560377@qq.com
- Country
- China
- ProdList
- 333
- Advantage
- 58
- Tel
- 13070690626
- admin@mopaikeji.com
- Country
- China
- ProdList
- 10689
- Advantage
- 58
- Tel
- 13296077563 13296077563
- hr@bettersyn.com
- Country
- China
- ProdList
- 9932
- Advantage
- 58
- Tel
- 13356310019 13356310019
- boyu2024@163.com
- Country
- China
- ProdList
- 3195
- Advantage
- 58
- Tel
- 0372-15803728682 15803728682
- hnkmy2023@163.com
- Country
- China
- ProdList
- 517
- Advantage
- 58
- Tel
- 021-50795510 4000665055
- sy-c5@accelachem.com
- Country
- China
- ProdList
- 10120
- Advantage
- 58
- Tel
- 19588588067 19588588067
- 19588588067@163.com
- Country
- China
- ProdList
- 9751
- Advantage
- 58
- Tel
- 18143011203
- ET-market@chemextension.com
- Country
- China
- ProdList
- 25952
- Advantage
- 58
- Tel
- 18317763565
- 18317763565@163.com
- Country
- China
- ProdList
- 8933
- Advantage
- 58
- Tel
- 13611955358 13611955358
- yanfen2024@126.com
- Country
- China
- ProdList
- 1238
- Advantage
- 58
- Tel
- 0573-83568680 18057391398
- 3956524501@qq.com
- Country
- China
- ProdList
- 1442
- Advantage
- 58
- Tel
- +86-15680926068 +86-15680926068
- 1924344760@confluore.cn
- Country
- China
- ProdList
- 2996
- Advantage
- 58
- Tel
- +undefined18143011203
- info@chemextension.com
- Country
- China
- ProdList
- 42056
- Advantage
- 58
- Tel
- +86-0533-2185556 +8617865335152
- Mandy@hangyubiotech.com
- Country
- China
- ProdList
- 10986
- Advantage
- 58
View Lastest Price from Bis-PEG6-NHS ester manufacturers
- Product
- Bis-PEG6-NHS ester 1526718-98-8
- Price
- US $0.00/g
- Min. Order
- 5g
- Purity
- >98.00%
- Supply Ability
- 5g
- Release date
- 2024-03-25