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DC4 Crosslinker

Product Name
DC4 Crosslinker
CAS No.
1374647-94-5
Chemical Name
DC4 Crosslinker
Synonyms
DC4 Crosslinker;AJWAJFDEYIAPKX-UHFFFAOYSA-L;1,4-bis[4-[(2,5-dioxo-1-pyrrolidinyl)oxy]-4-oxobutyl]-1,4-diazoniabicyclo[2.2.2]octane,dibromide;(2,5-Dioxopyrrolidin-1-yl) 4-[4-[4-(2,5-dioxopyrrolidin-1-yl)oxy-4-oxobutyl]-1,4-diazoniabicyclo[2.2.2]octan-1-yl]butanoate, dibromi de
CBNumber
CB63152601
Molecular Formula
C22H32Br2N4O8
Formula Weight
640.319
MOL File
1374647-94-5.mol
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DC4 Crosslinker Property

solubility 
DMSO: 11 mg/ml; PBS (pH 7.2): 3 mg/ml
form 
A crystalline solid
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
14734
Product name
DC4 Crosslinker
Purity
≥98%
Packaging
5mg
Price
$63
Updated
2024/03/01
Cayman Chemical
Product number
14734
Product name
DC4 Crosslinker
Purity
≥98%
Packaging
10mg
Price
$117
Updated
2024/03/01
Cayman Chemical
Product number
14734
Product name
DC4 Crosslinker
Purity
≥98%
Packaging
25mg
Price
$275
Updated
2024/03/01
AK Scientific
Product number
7904EJ
Product name
(2,5-Dioxopyrrolidin-1-yl)4-[4-[4-(2,5-dioxopyrrolidin-1-yl)oxy-4-oxobutyl]-1,4-diazoniabicyclo[2.2.2]octan-1-yl]butanoate;dibromide
Packaging
25mg
Price
$403
Updated
2021/12/16
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DC4 Crosslinker Chemical Properties,Usage,Production

Description

DC4 crosslinker is a mass spectrometry-cleavable crosslinking reagent (18? in length) that contains two intrinsic positive charges, which allow cross-linked peptides to fragment into their component peptides by collision-induced dissociation or in-source decay.1 Initial fragmentation events result in cleavage on either side of the positive charges so that cross-linked peptides can be identified as pairs of ions separated by defined masses.1 Additionally, these two intact peptide fragments can be further fragmented to yield a series of b- and y-ions for peptide identification.1

Uses

DC4 Crosslinker is a stable crosslinking reagent with improved activity and solubility. DC4 Crosslinker is labile cleavable with collision-induced dissociation (CID), that will be fragmented into four rearrange products containing mobilized protons[1].

References

1. Clifford-Nunn, B., Showalter, H.D., and Andrews, P.C. Quaternary diamines as mass spectrometry cleavable crosslinkers for protein interactions J. Am. Soc. Mass Spectrom. 23(2),201-212(2012).

DC4 Crosslinker Preparation Products And Raw materials

Raw materials

Preparation Products

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DC4 Crosslinker Suppliers

China 23 United States 1 Global 24
Cayman Chemical Company
Tel
--
Fax
--
Email
cayman@caymanchem.com
Country
United States
ProdList
6213
Advantage
81

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  • DC4 Crosslinker
  • AJWAJFDEYIAPKX-UHFFFAOYSA-L
  • 1,4-bis[4-[(2,5-dioxo-1-pyrrolidinyl)oxy]-4-oxobutyl]-1,4-diazoniabicyclo[2.2.2]octane,dibromide
  • (2,5-Dioxopyrrolidin-1-yl) 4-[4-[4-(2,5-dioxopyrrolidin-1-yl)oxy-4-oxobutyl]-1,4-diazoniabicyclo[2.2.2]octan-1-yl]butanoate, dibromi de
  • 1374647-94-5